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Objectives: The characteristic clinical symptoms of collagenous colitis are non-bloody diarrhoea, urgency and abdominal pain. Treatment is aimed at reducing the symptom burden and the disease impact on patients' health-related quality of life. The objective of this study was to analyse health-related quality of life in patients with collagenous colitis. Methods: In a cross-sectional, postal HRQL s
Objective. To analyse patients' self-reported reasons for not adhering to physical activity referrals (PARs). Design and setting. Data on 1358 patients who did not adhere to PARs were collected at 38 primary health care (PHC) centres in Sweden. Intervention. PHC providers issued formal physical activity prescriptions for home-based activities or referrals for facility-based activities. Subjects. O
Members of the TALE (Three-amino acid loop extension) family of atypical homeodomain-containing transcription factors are important downstream effectors of oncogenic fusion proteins involving the mixed lineage leukemia (MLL) gene. A well-characterized member of this protein family is MEIS1, which orchestrates a transcriptional program required for the maintenance of MLL-rearranged acute myeloid le
Aberrant dopaminergic signaling is a critical determinant in multiple psychiatric disorders, and in many disease states, dopamine receptor number is altered. Here we identify a molecular mechanism that selectively targets D2 receptors for degradation after their activation by dopamine. The degradative fate of D2 receptors is determined by an interaction with G protein coupled receptor-associated s
Chondromodulin I (chm-I), a type II transmembrane protein, is highly expressed in the avascular zones of cartilage but is downregulated in the hypertrophic region, which is invaded by blood vessels during enchondral ossification. In vitro and in vivo assays with the purified protein have shown chondrocyte-modulating and angiogenesis-inhibiting functions. To investigate chm-I function in vivo, we g
This study aimed to examine the relationship between craniofacial dysmorphology and anomalies of brain morphology in schizophrenia. Assessments of craniofacial dysmorphology and magnetic resonance imaging of brain were performed independently of each other and blind to each other in 24 males with schizophrenia and 16 male controls. Ventricular cerebrospinal fluid volume was negatively correlated w
The purpose of the study was to describe digital artists’ notions about their physical work environment in an organizational context. It is suggested that digital artists are creative professionals that use personal, creative imagination and skills to practice problem-solving by producing artistic artifacts. Based on four in-depth interviews and nine email interviews a qualitative research effort
The importance of supply chains and the dissemination of EMS concept trigged this research to explore the environmental supply chain requirements, the way these requirements are controlled and to reveal the potential interface with EMS. The focus of this research has been in supply chains in Sweden and Poland. Interviews were conducted with companies of various sectors and members of the consultan
The refugee status determination procedure involves complex issues of both law and fact. The process becomes even more complicated when facts arise that give indications on the possible applicability of article 1.F of the Refugee Convention. In this case the decision-maker has to decide on the one hand if the applicant qualifies for refugee status and on the other hand if there are serious reasons
Employee benefits can be seen as an HRM practice that has received increased attention among practitioners, while scholars’ interest in this theme has been moderate. The previous research focus has mostly been on how benefits contribute to organizational outcomes such as commitment, retention and attraction of employees. As opposed to this dominant view, this study sets out to explore employee ben
The Church has been a dominant actor in the history of care and social support, but it met several restrictions during the 20th Century. The Church of Sweden now has,since the separation from the state A.D. 2000, the possibility to act as a "welfare entrepreneur". But the willingness to do so seems limited. Even if innovative examples are seen the parishes hesitate for organisational and ideologic
Seismic refraction imaging is a technique that has seen an increase of applications in engineering during recent years. In the work presented here a case of refraction tomography in the city of Copenhagen is discussed. The survey included two modalities; 1. a surface survey where 13.9 kilometers of crooked lines along segments of the planned underground metro were mapped, 2. borehole “walk-away” s
