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Gold mining causes various negative social and environmental impacts in countries of extraction like Colombia. Voluntary and legal efforts to tackle these challenges have recently increased in Europe. To understand the complex supply chain and the impact of the newly evolved governance structures better, more research is needed. Based on a literature review and interviews, I identify important Eur
SpoVD and PBP4b are structurally very similar high-molecular-weight, class B penicillin-binding proteins produced early during sporulation in Bacillus subtilis. SpoVD is known to be essential for endospore cortex synthesis and thereby the production of heat-resistant spores. The role of PBP4b is still enigmatic. Both proteins are synthesized in the cytoplasm of the mother cell. PBP4b remains in th
Background: The classic Bernard-Soulier syndrome (BSS) is a rare inherited thrombocytopenia (IT) associated with severe thrombocytopenia, giant platelets, and bleeding tendency caused by homozygous or compound heterozygous variants in GP1BA, GP1BB, or GP9. Monoallelic BSS (mBSS) associated with mild asymptomatic macrothrombocytopenia caused by heterozygous variants in GP1BA or GP1BB may be a frequ
The polymerization of amino acids into proteins occurs on ribosomes, with the rate influenced by the amino acids being polymerized. The imino acid proline is a poor donor and acceptor for peptide-bond formation, such that translational stalling occurs when three or more consecutive prolines (PPP) are encountered by the ribosome. In bacteria, stalling at PPP motifs is rescued by the elongation fact
Understanding the role of technology characteristics and the context in the diffusion of new energy technologies is important for assessing feasibility of climate mitigation. We examine the historical adoption of nuclear power as a case of a complex large scale energy technology. We conduct an event history analysis of grid connections of first sizable commercial nuclear power reactors in 79 count
Abstract in Uncoded languagesIn this article we discuss four basic approaches to characterising droughts namely meteorological, hydrological, agricultural, and socioeconomic. In the first three approaches, drought is defined and measured as a physical phenomenon primarily related to the precipitation shortfall. Socioeconomic drought, nonetheless, is described and determined as the 'supply' and 'de
Seeking to examine the implications of social distancing, isolation and the silencing of public spaces brought about by the COVID-19 epidemic, I offer an interpretation of Kafka’s short story ‘The Silence of the Sirens’ contrasting it to the Homeric original. In Homer’s story, Odysseus resists the temptation of the Sirens’ deadly song by having himself tied to the mast of his ship, while his oarsm
Urban spatial development is a crucial issue for spatial planning and urban governance, ultimately determining cities’ sustainability. While a set of spatial strategies to address urban development are progressively gaining international consensus, their actual applicability is still contested. An interesting test-bed is represented by the European Union (EU), where common spatial strategies have
The standard way today to obtain measures of inflationary expectations is to use questionnaires to ask a representative group of respondents about their beliefs of the future rate of inflation during the coming 12 months. This type of data on inflationary expectations as well as on inflationary perceptions has been collected in a unified way on an EU-wide basis for several years. By now, probably
The introduction of the euro as a currency in physical existence in January 2002 was a major step in the European integration process. The purpose of this paper is to explore how a representative selection of 12 000 Europeans across all countries in the euro area view the effects of the euro five years after its introduction. The empirical analysis uses multinomial logistic regressions to explore
The ways in which expectations for the future shape how actors and organizations make sense of the present has received growing interest and attention among science and technology scholars – with particular attention being paid to the role of expectations and prediction making in technology and finance. Nevertheless, while the imaginaries involved in the futures described by tech-entrepreneurs and
Keynote speech of a conference organized by the Swedish Network for European Legal Studies (SNELS)
An important manifestation of severe COVID-19 is the ARDS-like lung injury that is associated with vascular endothelialitis, thrombosis, and angiogenesis. The intravascular innate immune system (IIIS), including the complement, contact, coagulation, and fibrinolysis systems, which is crucial for recognizing and eliminating microorganisms and debris in the body, is likely to be involved in the path
The future role of AI in healthcare is largely seen as positive, inevitable, necessary, and driven by the private sector. These dominant narratives obscure decision-making about these future applications, with little room for political scrutiny, or public participation. Public, and private resources, are being funnelled to support various AI health technologies. By prioritising some and not others
Background: Timely treatment of acute allergic reactions (AARs) is important to minimize reaction severity. Corticosteroid tablets dissolved in water are commonly used in mainstay treatment. A new oral film that dissolves on the tongue provides a faster and less cumbersome alternative to tablets for corticosteroid administration during AARs. This study evaluated patients' preferences for attribute
Objective: The number of type-II endometrial cancer patients has been increasing and the prognosis is not favorable. We aim to investigate whether sarcopenia index in any of several different muscles could serve as a novel biomarker of prognosis in patients with type-II endometrial cancer. Methods: We retrospectively investigated a total of 194 patients at four hospitals. Ninety patients were trea
Purpose: A pilot study to identify bacterial biofilm in the lacrimal sacs of patients with chronic dacryocystitis, and in patients with epiphora but without discharge, using scanning electron microscopy. Methods: Five patients: two with nasolacrimal duct obstruction without dacryocystitis, and three with dacryocystitis refractory to antibiotics, underwent external dacryocystorhinostomy. One contro
