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We have previously reported that the C-Med 100® extract of the plant Uncaria tomentosa induces prolonged lymphocyte half life and hence increased spleen cell number in mice receiving the extract in their drinking water. Further, the extract induces cell proliferation arrest and inhibits activation of the transcriptional regulator nuclear factor κB (NF-κB) in vitro. We now report that mice exposed
A large protein was purified from bovine kidney, using selective extraction with EDTA to solubilize proteins anchored by divalent cation-dependent interactions. An antiserum raised against the purified protein labeled the apical cell surface of the epithelial cells in proximal tubules and the luminal surface of small intestine. Ten peptide sequences, derived from the protein, all matched the recen
In the soil bacterium Bacillus subtilis Spx is a key regulator that controls expression, positively or negatively, of several genes in response to certain oxidative stresses that lead to the formation of unwanted disulphide bonds. Here we characterized the yjbH gene and show that it encodes a novel effector of Spx. The yjbH gene is part of the yjbIH operon that encodes a truncated haemoglobin (Yjb
Abstract. Effects of enhanced UV-B (representing a 15% ozone depletion) on cyanobacterial nitrogen fixation were measured at a high arctic site (Adventdalen, 79°N, Svalbard) and a subarctic site (Abisko, 68°N, Sweden). Nitrogen fixation potential (acetylene reduction) by cyanobacteria associated with the moss Sanionia uncinata in vegetation exposed to experimentally enhanced levels of UV-B for 3 a
Stress-related exhaustion is an increasingly focused phenomenon, although scientifically not yet fully conceptualised. This is perhaps partly due to the fact that the distinction between exhaustion and other already established concepts, such as depression, is not clear. This study explores whether exhaustion can be differentiated from depression and anxiety, by means of introducing the SF-36 vita
Single-nucleotide polymorphisms (SNPs) in the major histocompatibility complex class II transactivator (MHC2TA) gene encoding the class II transactivator have been associated with multiple sclerosis, rheumatoid arthritis, and myocardial infarction in the Swedish population. We used a case-control approach to investigate the prevalence of a relevant variant in Swedish systemic lupus erythematosus (
Previous Icelandic studies reported that single nucleotide polymorphisms (SNPs) in the phosphodiesterase 4D (PDE4D) region and the 5-lipoxygenase activating protein ALOX5AP were associated with ischaemic stroke, whereas other studies reported ambiguous findings. We examined 932 ischaemic stroke patients from a Swedish population-based stroke register, and 396 control subjects. We assessed possible
The pathophysiology behind gastrointestinal dysmotility in diabetes mellitus is unknown. Both esophageal dysmotility and gastroparesis have been shown to be associated with retinopathy, suggesting that microangiopathy is important in the common etiology. The aim of the present study was to examine whether patients with diabetes exhibit microangiopathy in the colon, and if present, to correlate mic
The purpose of the study was to increase self-archiving of scientific articles in Swedish open archives and thus contribute to the dissemination and increased visibility of Swedish research and to a greater impact for the individual researcher. We wanted to find out what obstacles may occur in the self-archiving process and how the database SHERPA/RoMEO functions as support for control of the publ
Abstract in Italian Sono qui messi a confronto due modelli per l’analisi dei Vangeli da un punto di vista retorico: l’utilizzo delle categorie retoriche dei Progymnasmata ellenistici e «la retorica biblica e semitica». Si sostiene che l’utilizzo di un modello non escluda l’utilizzo dell’altro, ma che anzi si completino a vicenda. Un’analisi dell’ultima cena in Lc 22,11-38 serve a illustrare l’uso Two approaches to the rhetorical analysis of Gospel texts are being compared in this essay: on the one hand, the use of the rhetorical categories of the Hellenistic Progymnasmata, and on the other, «Biblical and semitic rhetoric». It is argued that these two approaches are not mutually exclusive, but complementary. The last supper in Luke 22,14-38 functions as a test case. An introduction offers s
Objective. To assess lung cancer risk in systemic lupus erythematosus (SLE), relative to demographics, drug exposures, smoking, and disease activity. Methods.We analyzed data from 14 SLE cohorts. We calculated adjusted HR estimates for lung cancer in SLE, relative to demographics, smoking, time-dependent medication exposures, and cumulative disease activity [mean adjusted SLE Disease Activity Inde
Tuberculosis has been reaffirmed as the infectious disease causing most deaths in the world. Co-infection with HIV and the increase in multi-drug resistant Mycobacterium tuberculosis strains complicate treatment and increases mortality rates, making the development of new drugs an urgent priority. In this study we have identified a promising candidate by screening antimicrobial peptides for their
