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OBJECTIVE(S):: We explored incidence, predictors, and long-term prognosis of hospital admissions attributed to reflex syncope and orthostatic hypotension. METHODS:: We analyzed a cohort of 32?628 individuals (68.2% men; age, 45.6?±?7.4 years) without prevalent cardiovascular disease over a follow-up period of 26.6?±?7.5 years. RESULTS:: One thousand and fourteen persons (3.1%, 1.2 per 1000 person-
Artros är en vanligt förekommande ledsjukdom som kan leda till stelhet ochsmärta i den drabbade leden. Sjukdomen innebär att det sker en nedbrytning av det brosk som fungerar som smörjmedel och skyddande lager runt benändarna i leden. Nedbrytningen av brosket sker gradvis under flera år och oftast upptäcker man sjukdomen först i ett sent stadium när man börjar känna smärta eller få problem med rörOsteoarthritis (OA) is a degenerative disease that affects articular cartilage, which covers the surfaces of the bones in synovial joints. At later stages the disease can result in major loss of articular cartilage and thus lead to major disability. In order to allow for an early detection and treatment of OA, it is necessary to better understand the rather subtle biochemical changes in the cartil
Purpose - The purpose of this study is to provide a new perspective for effective management of the merger and acquisition (M&A) process by making use of a case study of a merger in the Japanese pharmaceutical industry. As corporate governance and culture are notably employee-oriented in Japanese firms, the paper seeks to explore whether M&As in the industry may follow different paths from
Wohlers Associates, Inc., recognized widely as the leading consulting firm and preeminent authority on additive manufacturing and 3D printing worldwide—terms that are used interchangeably—today announced the publication of the Wohlers Report 2016. The 2016 edition marks the 21st consecutive year of its availability. According to Wohlers Report 2016, the additive manufacturing (AM) industry, consis
If an accident or attack involving radiological or nuclear material were to happen, people from the general public would be at risk of exposure to ionising radiation. Unlike people working with ionising radiation, for whom level of exposure to radiation is constantly monitored with dosemeters, people from the general population do not wear dosemeters; thus, the dose estimations for these individua
Mining, seen as a source of revenue in most developing countries, threatens seriously the environment. Mining impacts the water quality and one of the main problems of mining is acid mine drainage. Low pH and high concentration of heavy metals characterize acid mine drainage. When a stream is impacted by acid mine drainage both human activities and the ecological system are seriously affected. In
Increasing efforts to produce power from renewable resources and improve the efficiency of current industrial processes have turned the spotlight on organic Rankine cycles (ORC). The use of refrigerant mixtures in these cycles offers a wide range of possibilities for fluid selection and optimization. Moreover, zeotropic mixtures are reported to yield better cycle performances due to their better t
Abstract Aim: To investigate trends in mortality and morbidity in very preterm infants. Methods: Population-based perinatal register; liveborn infants 22 + 0 to 31 + 6 gestational weeks were investigated (time period 1995-2004). Time trends for mortality and common morbidities were explored using logistic regression analyses. Results: Data from 1614 liveborn infants were included. There was an inc
This is the first part of a series of papers devoted to direct and inverse scattering of transient waves in lossy inhomogeneous media. The medium is assumed to be stratified, i.e., it varies only with depth. The wave propagation is modeled in an electromagnetic case with spatially varying permittivity and conductivity. The objective in this first paper is to analyze properties of the scattering op
BACKGROUND: Liver resection is a possibly curative treatment for colorectal cancer (CRC) liver metastases. Preoperative chemotherapy may make initially irresectable tumors resectable. The aim of this study was to compare perioperative course and short-term mortality after liver resection for CRC metastases between patients who were and were not treated with preoperative chemotherapy. METHODS: Pati
Objectives: The aims of this study were to evaluate the community-based prevalence of atrial fibrillation (AF) in a western society using a geographically well-defined population in the northern part of Sweden as a reference and to estimate the proportion of patients eligible for oral anticoagulation (OAC) prophylactic therapy according to the stroke risk indices CHADS(2) and CHA(2) DS(2) -VASc. B
Objective: An association between small for gestational age (SGA) and risk for celiac disease (CD) in childhood has previously been reported. However, this association may reflect residual confounding by genetic or environmental factors. For example, presence of subclinical CD in the mother might be a common cause of both SGA and CD in the offspring. We investigate whether SGA is causally associat
A diagnosis of malignant hyperthermia (MH) can be determined by performing an in vitro (muscle) contracture test (IVCT) or by identifying a known MH causative mutation in the ryanodine receptor 1 gene (RYR1). Genetic diagnosis has an advantage over IVCT because it is less invasive. Direct sequencing of the very large RYR1 coding region (15.117 bases) is a laborious and expensive task. In this stud
Since the publication of the European League Against Rheumatism recommendations for the pharmacological treatment of psoriatic arthritis (PsA) in 2012, new evidence and new therapeutic agents have emerged. The objective was to update these recommendations.
Society is becoming increasingly dynamic and complex, and therefore more vulnerable. It is thus important that society is resilient in order to be able to protect citizens and critical functions in the wake of disasters. It has been suggested that disaster risk reduction (DRR) is key in establishing resilience, and that adequate capacity in DRR is vital to reduce the effects of disasters. DRR and
The fire technical properties of products are determining factors for the initiation and growth of fires. Measurement of fire technical properties and the understanding of how they relate to real hazards are therefore important for fire safety. This work deals with the fire technical properties of building products, their tendency to ignite and release heat in different fire scenarios. Building p
We present a model for estimating the final keep/cancel decision point, on a per-feature basis, for scope inclusion in a future release. The Basic Lost Opportunity Estimation Model (BLOEM), based on data from a company that uses an agile-inspired software development model, supports feature selection when the time-dependent business value estimates change as the requirements analysis progresses. T
2,8-Dihalo substituted analogues of Tröger’s base were prepared via the Tröger’s base condensation reaction. These compounds were used as synthetic intermediates for the preparation of otherwise inaccessible functionalized Tröger’s base analogues. Based on 2,8-diiodo-4,10-dimethyl-6H,12H-5,11-methanodibenzo[b,f][1,5]diazocine, a mild room temperature protocol for the introduction of terminal func
