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The electronic structure of strongly correlated systems is usually calculated by using an effective model Hamiltonian with a small number of states and an effective on-site interaction. The mode, however, neglects the frequency dependence of the interaction, which emerges as a result of dynamical screening processes not included in the model. The self-energy calculated in this kind of model within
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This thesis investigates speech production and self-monitoring by using a newly constructed Real-time Speech Exchange (RSE) system. This system makes it possible to covertly manipulate the auditory feedback that participants receive of their own voice. First a word or utterance made by the participant is recorded, and later in the test this recording is inserted into their auditory feedback with p
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Aim: This is the first study to evaluate compliance with the 2003 Swedish national guidelines for prophylactic treatment of respiratory syncytial virus (RSV) in children with congenital heart disease (CHD). We estimated the relative risk (RR) of children with CHD being hospitalised with a RSV infection, studied the extent to which RSV prophylactic treatment with palivizumab corresponded to the gui
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Understanding factors that limit gene flow through the landscape is crucial for conservation of organisms living in fragmented habitats. We analysed patterns of gene flow in Elater ferrugineus, an endangered click beetle living in old-growth, hollow trees in a network of rural avenues surrounded by inhospitable arable land. Using amplified fragment length polymorphism (AFLP) data, we aimed to eval
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Background: Tumor associated macrophages (TAMs) are alternatively activated macrophages that enhance tumor progression by promoting tumor cell invasion, migration and angiogenesis. TAMs have an anti-inflammatory function resembling M2 macrophages. CD163 is regarded as a highly specific monocyte/macrophage marker for M2 macrophages. In this study we evaluated the specificity of using the M2 macroph
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Traditional, pre-industrial farming was adapted to the natural environment-topography, geology, hydrology, climate, and biota. Traditional land use systems are still to be traced in Scandinavia as an "infield/outland landscape", and in Japan as a "Satoyama landscape." There are obvious similarities and differences in land use-the main difference being that pasturing of cattle and sheep has been le
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Background. According to EU legislation, 26 fragrance substance allergens must be labelled on cosmetic products. For 12 of them, the optimal patch test concentration/dose has not been evaluated. Objectives. To establish the optimal patch test doses in mg/cm(2) for the 12 fragrance substances that are not included in fragrance mix I or II in the European baseline patch test series. Materials and Me
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It is important to identify the patients at highest risk of fractures. A recent large-scale meta-analysis identified 63 autosomal single-nucleotide polymorphisms (SNPs) associated with bone mineral density (BMD), of which 16 were also associated with fracture risk. Based on these findings, two genetic risk scores (GRS63 and GRS16) were developed. Our aim was to determine the clinical usefulness of
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In response to the 2012 KDIGO (Kidney Disease: Improving Global Outcomes) guideline for blood pressure management in patients with chronic kidney disease not on dialysis, the National Kidney Foundation organized a group of US experts in hypertension and transplant nephrology to review the recommendations and comment on their relevancy in the context of current US clinical practice and concerns. Th
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A Task Group within the ICRP Committees 2 and 3 is continuously working to improve absorbed dose estimates to patients investigated with radiopharmaceuticals. The work deals with reviews of the literature, initiation of new or complementary studies of the biokinetics of a compound and dose estimates. Absorbed dose calculations for organs and tissues have up to now been carried out using the MIRD f
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This paper verified the macro-to-mini-scale criterion BoRe10.5=200 because data points where BoRe10.5≤200 and BoRe10.5>200 show very different trends for the entire database (1672 data points). Boiling number at critical heat flux (Blchf) decreases greatly with heated length-to-diameter ratio (Lh/dhe) when Lh/dhe is small while a relatively smooth trend occurs with large Lh/dhe values. The paper p
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Synthetic molecular motors typically take nanometer-scale steps through rectification of thermal motion. Here we propose Inchworm, a DNA-based motor that employs a pronounced power stroke to take micrometer-scale steps on a time scale of seconds, and we design, fabricate, and analyze the nanofluidic device needed to operate the motor. Inchworm is a kbp-long, double-stranded DNA confined inside a n
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A search for pair-produced third generation scalar leptoquarks is presented, using proton-proton collisions at root s = 7 TeV at the LHC. The data were recorded with the ATLAS detector and correspond to an integrated luminosity of 4.7 fb(-1). Each leptoquark is assumed to decay to a tau lepton and a b-quark with a branching fraction equal to 100%. No statistically significant excess above the Stan
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Serglycin (SG) is a proteoglycan expressed by hematopoietic cells and is constitutively secreted by multiple myeloma (MM) cells. SG participates in the regulation of various inflammatory events. We found that SG secreted by human MM cell lines inhibits both the classical and lectin pathways of complement, without influencing alternative pathway activity. The inhibitory effect of SG is due to direc
