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A population of atypical CD56(-)CD16(+) natural killer cells is expanded in PTSD and is associated with symptom severity

INTRODUCTION: Post-traumatic stress disorder (PTSD) has been associated with immune disturbances, including a higher incidence of infections and autoimmune diseases as well as a net pro-inflammatory state. Natural killer (NK) cells, a key component of the innate immune system, have been less well-studied in PTSD despite their importance in immunity.METHODS: We studied two independent samples of co

Imaging the master regulator of the antioxidant response in non-small cell lung cancer with positron emission tomography

Mutations in the NRF2-KEAP1 pathway are common in non-small cell lung cancer (NSCLC) and confer broad-spectrum therapeutic resistance, leading to poor outcomes. The cystine/glutamate antiporter, system xc-, is one of the >200 cytoprotective proteins controlled by NRF2, which can be non-invasively imaged by (S)-4-(3-18F-fluoropropyl)-l-glutamate ([18F]FSPG) positron emission tomography (PET). Throu

Alignment of clinical breast tomosynthesis and mechanical images : The effect of the variation in shift and rotation

Simultaneous digital breast tomosynthesis and mechanical imaging (DBTMI), a novel screening approach, combines anatomic DBT with functional analysis of the stress distribution on the compressed breast by mechanical imaging (MI). Preliminary studies suggest potential to reduce false positive findings. DBTMI requires to align DBT and MI images. In this study, we have analyzed robustness to alignment

Evaluating an image restoration pipeline for digital mammography across varied radiation exposures and microcalcification sizes using model observer analysis

In this study, we assess the impact of an image restoration pipeline, designed for digital mammography, on the detectability of microcalcifications of different sizes across varied radiation exposures. The restoration pipeline first removes the noise of the image considering a Poisson-Gaussian noise model that incorporates quantum and electronic noise. Then, it appropriately merges the noisy and d

Programming support for reconfigurable custom vector architectures

High performance requirements increased the popularity of unconventional architectures. While providing better performance, such architectures are generally harder to program and generate code for. In this paper, we present our approach to ease programmability and code generation for such architectures. We present a domain specific language (DSL) for the programming part, and a constraint programm

p53-dependent and -independent differentiation of leukemic U-937 cells : relationship to cell cycle control

Observations based on overexpression of the suppressor gene p53 or interference with endogenous p53 support a role for p53 in mediating not only growth inhibition and apoptosis but also differentiation. The aim of this study was to characterize the mechanisms of p53-dependent differentiation in the monoblastic leukemia cell line U-937. These cells were transfected with a mutant of the p53 gene exp

A method for supporting the integration of packaging development into product development

This paper aims to support the decision-making tasks regarding the integration of packaging development into product development. Based on the study of the interactions of the product and packaging during the whole product life cycle, a set of packaging-related factors was extracted and mapped to a general product development model, which at a strategic level can be used to define an integrated pr

Diamonds for X-ray optical applications at 3rd and 4 th generation X-ray sources

There is currently interest in low strain HPHT diamond due to its expected application as various types of X-ray optical elements at Synchrotrons, where the X-ray intensity is becoming progressively too severe for the existing materials. The diamond crystals need to be synthesised with unprecedented lattice quality. In recent measurements at the ID19 beamline of European Synchrotron Radiation Faci

Evaluation of a flat fielding method for simultaneous DBT and MI acquisition

We are developing a prototype system for simultaneous digital breast tomosynthesis (DBT) and mechanical imaging (MI). MI maps the local pressure distribution during clinical exams, to distinguish breast abnormalities from the normal tissue. Both DBT alone, and MI when combined with digital mammography, have demonstrated the ability to reduce false positives; however, the benefit of combining DBT w

Characterization of the P13 membrane protein of Borrelia burgdorferi by mass spectrometry

Borrelia burgdorferi sensu lato is a tick-borne pathogen that causes Lyme disease. The characterization of membrane proteins from this and other pathogens may yield a better understanding of the mechanisms of infection and information useful for vaccine design. Characterization of the highly hydrophobic Borrelia outer membrane component P13 from a mutant (OspA- OspB- OspC- and OspD-) strain was un

Estimated dietary exposure to pesticide residues based on organic and conventional data in omnivores, pesco-vegetarians, vegetarians and vegans

PURPOSE: To examine dietary exposure to 25 pesticide residues in several diet groups including omnivores, pesco-vegetarians, vegetarians and vegans while accounting for the farming system (organic or conventional) of plant-based foods consumed.METHODS: Organic and conventional consumption data in combination with data on pesticide residues in plant-based foods were used to derive estimated dietary

Simultaneous digital breast tomosynthesis and mechanical imaging in women recalled from screening - A preliminary analysis

We have developed a method for simultaneous tomosynthesis and mechanical imaging, called DBTMI. Mechanical imaging measures the stress distribution over the compressed breast surface. Malignant tissue is usually stiffer than benign, which results in higher stress on the compressed breast and enables to distinguish malignant from benign findings. By combining tomosynthesis and mechanical imaging, w

Tumor growth rate estimations in a breast cancer screening population

Tumor growth rate estimations can provide useful information about tumor progression and aggressiveness. Understanding the breast cancer progression and aggressiveness could aid with personalized screening/follow-up, treatment options, and prognosis. This paper reports a preliminary estimation of the tumor volume doubling time (TVDT) for cancers detected during the Malmö Breast Tomosynthesis Scree

Evaluation of 3D printed contrast detail phantoms for mammography quality assurance

Objects created by 3D printers are increasingly used in various medical applications. Today, affordable 3D printers, using Fused Deposition Modeling are widely available. In this project, a commercially available 3D printer was used to replicate a conventional radiographic contrast detail phantom. Printing materials were selected by comparing their x-ray attenuation properties. Two replicas were p

How to age right and care(fully) at home? : A protocol for a multistage comparative study of ageing in place and hospital at home care across three countries

INTRODUCTION: Ageing right care(fully) is a transnational research study which explores and maps an understanding of the care pathways between ageing in place and hospital at home policy and practices for older adults in Israel, the Netherlands and Sweden. The countries are suited to be compared where they have growing, ageing populations, a focus on healthcare reform and several policies to reduc

Publication in brain

OP-BRAI160351 1..15 Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli Daniel Tornero,1 Oleg Tsupykov,2 Marcus Granmo,3 Cristina Rodriguez,1 Marita Grønning- Hansen,1 Jonas Thelin,3 Ekaterina Smozhanik,2 Cecilia Laterza,1 Somsak Wattananit,1 Ruimin Ge,1 Jemal Tatarishvili,1 Shane Grealish,4 Oliver Brüstle,5 Galina Skibo,2 Malin Parmar

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_brain.pdf - 2026-05-25

Arbetsordning 20111111

Arbetsordning LUNDS UNIVERSITET 3ARBETSORDNING FÖR LUNDS UNIVERSITET Dnr LS 2010/625 11 november 2011 Arbetsordning för Lunds universitet Med stöd av 2 kap. 2 § första stycket 8p högskoleförordningen (1993:100), nedan HF, fastställer Lunds universitet följande arbetsordning. 4 Inledning Inom samtliga nämnder, styrelser och övriga organ inom Lunds universitet ska det råda balans mellan könen. Med b

https://www.lu.se/sites/www.lu.se/files/arbetsordning_20111111.pdf - 2026-05-25

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Årsberättelse 20 24 / VATTENHALLEN SCIENCE CENTER / ÅRSBERÄTTELSE 2024 VATTENHALLEN SCIENCE CENTER / ÅRSBERÄTTELSE 2024 / Innehåll Året 2024..........................................................3 Om Vattenhallen................................................4 Besöksstatistik ...................................................5 Styrelse, vision och mål......................................6 Me

https://www.vattenhallen.lu.se/fileadmin/vattenhallen/MIRJAM/OmVattenhallen/VH_aarsberaettelse24_web.pdf - 2026-05-23

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0 Årsberättelse 2014 HT-fakulteternas biblioteksverksamhet BILD Under 2014 genomfördes flera förändringar vid HT-biblioteken. En mycket påtaglig och efterlängtad var sammanslagningen och flytten av fem bibliotek till LUX-biblioteket. Det nya LUX-biblioteket är mindre än SOL-biblioteket men man har utnyttjat lokalerna maximalt. Den tryckta boken är central inom HTs ämnen och det nya biblioteket dom

https://www.ht.lu.se/fileadmin/_migrated/content_uploads/2014_A__rsredovisning_HTbibl.pdf - 2026-05-23