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Förändring, stabilitet, managed competition

Den amerikanska staden Phoenix ligger omgiven av berg i Sun Valley, Arizona. Klimatet är varmt och glest utspridda kaktusar står som eldgafflar mot skyn. Tänk på en typisk Vilda Västern-film så får du en förnimmelse av vad som kännetecknar Phoenix omgivningar. Trots ökenlika förhållanden bor där idag 1,3 miljoner invånare. Befolkningstillväxten tog fart på allvar luftkonditioneringen introducerade

Forced expression of the Wilms tumor 1 (WT1) gene inhibits proliferation of human hematopoietic CD34(+) progenitor cells

The Wilms tumor gene (WT1) encodes a zinc-finger containing transcription factor present in primitive hematopoietic progenitor cells. WT1 is also highly expressed in most cases of acute myeloid leukemia. Moreover, WT1 can interfere with induced differentiation of leukemic cell lines. These data suggest a function of WT1 in the maintenance of a primitive phenotype and a role in leukemogenesis by in

Dynamics of forest soil chemistry

Popular Abstract in Swedish Mycken möda har under de senaste årtiondena lagts ner på forskning om försurande utsläpp och dess skadliga effekter på skogar, vattendrag och människor. Kritiska belastningsgränser, i folkmun kallat "vad naturen tål", har tagits fram och använts i europeiska förhandlingar om utsläppbegränsningar. För skogsekosystem baseras de kritiska belastningsgränserna för försurandeAcidification caused by emissions of Nitrogen and Sulphur and associated adverse effects on forest ecosystems has been an issue on the political agenda for decades. Temporal aspects of soil acidification and/or recovery can be investigated using the soil chemistry model SAFE, a dynamic version of the steady-state model PROFILE used in critical loads assessment on the national level, e.g. for Swede

Investigating hardware micro-instruction folding in a Java embedded processor

Bytecode folding is an effective technique for speeding up execution in Java virtual machines. This paper investigates a hardware implementation of the aforementioned technique on BlueJEP, a Java embedded processor. Since BlueJEP is a micro-programmed stack machine, we adopt a micro-instruction oriented approach, folding up to four microinstructions (corresponding to up to four bytecodes, on occas

Evaluating life: Working with ethical dilemmas in education for sustainable development

Codifications of human rights are widely understood as politically established instruments for evaluating human life. The call for such an apparatus emerges as a response to the age-old problem of social organization, constituting – in extension – a means by which to cope with the overall problem of survival. However, evaluating life is inherently problematic. It is problematic as it presupposes a

End-of-life care among older cancer patients with intellectual disability in comparison with the general population : a national register study

BACKGROUND: Increasing life expectancy for people with an intellectual disability (ID) is resulting in more persons with cancer and a greater need for end-of-life (EoL) care. There is a need for knowledge of health care utilisation over the last year of life to plan for resources that support a high quality of care for cancer patients with ID. Therefore, the aims of the study were to compare (1) h

Designing for including children in online health care consultations

Children can and should be encouraged to take an active part in their own care. With the introduction of online health care centers, where the main interaction is provided through digital consultations, the process for including the child must be revised. In addition to the medical and legal challenges, the digital interface needs to be designed so that the parent is encouraged to involve the chil

Therapy Effects in Cerebral Folate Transport Deficiency with Hypomyelination Monitored by Multimodal Quantitative MR-Imaging

Myelin-sensitive quantitative (q) MRI techniques including MT (3D FLASH) and DTI (single-shot STEAM) are of growing importance to study white matter (WM) disorders in childhood. Cerebral folate transport deficiency is an inherited, treatable WM disorder with hypomyelination, developmental regression, movement disturbances, and epilepsy. One patient with this diagnosis and severe phenotype was trea