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Genes encoding B lineage–restricted transcription factors are frequently mutated in B-lymphoid leukemias, suggesting a close link between normal and malignant B-cell development. One of these transcription factors is early B-cell factor 1 (EBF1), a protein of critical importance for lineage specification and survival of B-lymphoid progenitors. Here, we report that impaired EBF1 function in mouse B
Water is the matrix of life, and its confinement in nanocavities is a central topic from geophysics to nanotribology. Phyllosilicate layered minerals provide natural nanocavities for water due to their capacity to hydrate by confining water molecules in the interlamellar space. However, the hydration of phyllosilicates at the nanoscale is not a fully understood process and depends on the geologica
We study experimentally and with wave optics modelling the absorption of light in CsPbBr3perovskite nanowire arrays fabricated into periodic pores of an anodized aluminum oxide matrix, for nanowire diameters from 30 to 360 nm. First, we find that all the light that couples into the array can be absorbed by the nanowires at sufficient nanowire length. This behavior is in strong contrast to the expe
In two late Mesolithic cemeteries, dated to about 5000 BCE, at Skateholm, Scania in Sweden, some graves were found that contained clothing decorations, mainly in the form of tooth beads but also other animal parts that were used as embellishments. These are perforated front teeth, mostly from red deer but also wild boar and in rare occasions from elk and aurochs. The tooth beads were in female graIn two late Mesolithic cemeteries, dated to about 5000 bce, at Skateholm, Scania in Sweden, some graves were found that contained clothing decorations, mainly in the form of tooth beads but also other animal parts that were used as embellishments. These are perforated front teeth, mostly from red deer but also wild boar and on rare occasions from elk and aurochs. The tooth beads in female graves w
In the present study, we apply deterministic chaos theory to investigate nonlinear dynamics in monthly precipitation at Mokpo, Korea, after wavelet decomposition. The wavelet transform is used not only for removal of noise but also for extraction of low and high frequency components in the data, representing low-dimensional dynamics. In order to determine an appropriate decomposition level for the
Aim: The overall aim of was to investigate the impact of self-reportedallergic disease on physical activity (PA) and health-related quality oflife (HRQoL) among adolescents.Methods: A cross-sectional analysis of 1 181 adolescents aged 13-14years (251 with current allergic disease), participating in the baselineinvestigation of the Southern Sweden allergy cohort, including a surveywith questions on
Public sector services are audited, measured and ranked in order to improve quality and transparency and to prompt organizations to conform to normative definitions of quality. In Swedish eldercare, a nationwide user survey distributed by the public authorities to all eldercare users, designed to gauge user satisfaction, is a prominent example of this form of soft governance. The aim of the presen
Fe(III) complexes with N-heterocyclic carbene (NHC) ligands belong to the rare examples of Earth-abundant transition metal complexes with long-lived luminescent charge-transfer excited states that enable applications as photosensitizers for charge separation reactions. We report three new hexa-NHC complexes of this class: [Fe(brphtmeimb)2]PF6(brphtmeimb = [(4-bromophenyl)tris(3-methylimidazol-2-yl
Decision-makers and managers spend substantial amounts of funding everyday on various interventions aimed at management of the large carnivores, for example different measures to mitigate depredation on livestock, e.g., removal of carnivores and fencing of livestock (see Linnell et al. 1996 for an extensive review). Management of species that occur in low numbers is challenging as relatively small
Background. Ruling out acute myocardial infarction (AMI) in the emergency department (ED) is challenging. Studies have shown that a high-sensitivity cardiac troponin T (hs-cTnT) <5 ng/L or <6 ng/L at presentation (0 h) can be used to rule out AMI. The objective of this study was to identify whether an even higher hs-cTnT threshold can be used for a safe rule out of AMI in the ED. Methods. The deri
Background: Polygenic prediction studies in continental Africans are scarce. Africa’s genetic and environmental diversity pose a challenge that limits the generalizability of polygenic risk scores (PRS) for body mass index (BMI) within the continent. Studies to understand the factors that affect PRS variability within Africa are required. Methods: Using the first multi-ancestry genome-wide associa
Painful Pasts and U seful M em ories R em em bering and Forgetting in Europe Lund 2012 Edited by: Barbara Törnquist-Plewa & Niklas Bernsand CENTRE FOR EUROPEAN STUDIES AT LUND UNIVERSITY Painful Pasts and useful MeMories reMeMbering and forgetting in euroPe CFE Conference Papers Series No. 5 | Lund 2012 In order to bring research in Memory Studies conducted in the Nordic countries together, to con
https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfecp5.pdf - 2026-05-30
DEV122747 3166..3177 RESEARCH ARTICLE STEM CELLS AND REGENERATION Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor Marie E. Jönsson1,2, Jenny Nelander Wahlestedt2, Malin Åkerblom1, Agnete Kirkeby2, Josephine Malmevik1, Per Ludvik Brattaas1, Johan Jakobsson1,*,‡ and Malin Parmar2,*,‡ ABSTRACT MicroRNAs (miRNAs)
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/jonsson.pdf - 2026-05-30
Generating regionalized neuronal cells from pluripotency, a step-by-step protocol METHODS ARTICLE published: 03 January 2013 doi: 10.3389/fncel.2012.00064 Generating regionalized neuronal cells from pluripotency, a step-by-step protocol Agnete Kirkeby*, Jenny Nelander and Malin Parmar Department of Experimental Medical Science and Lund Stem Cell Center, Lund University, Lund, Sweden Edited by: Cla
This thesis examines the relationship between international law protecting refugees and national legislation in Sweden and in the UK. International protection is afforded by the 1951 Geneva Convention Relating to the Status of Refugees. But also general international human rights instruments are relevant. These include the Universal Declaration of Human Rights, the International Covenant on Civil
