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When training a deep learning model, the dataset used is of great importance to make sure that the model learns relevant features of the data and that it will be able to generalize to new data. However, it is typically difficult to produce a dataset without some bias toward any specific feature. Deep learning models used in histopathology have a tendency to overfit to the stain appearance of the t

BACKGROUND: Owing to the wide spread perception of a possible benefit from paclitaxel in the second-line situation the Nordic Gynecologic Oncology Group (NGOG) conducted two prospective phase II studies of paclitaxel single agent treatment (175 mg/m2, three-hour i.v. infusion with standard pre-medication every third week) in patients with relapsing or progressing epithelial ovarian cancer followin

The present study investigates goal side selection in soccer penalty kicking. Given the task of choosing which side of a soccer goal to best score, participants viewed realistic images of a soccer goal and goalkeeper. The goalkeeper’s position was systematically displaced along the goal line, and the lateral position of the goalmouth was systematically displaced in each image – to simulate changes

This chapter explores how nursing home managers grapple with local manifestations of the wicked problems that plague elderly care. It shows the tension between managers' lofty ideals of high-quality, individualized care and their continuous struggle to handle very basic troubles that ultimately appear to be grounded in a lack of resources, such as high personnel turnover and staff complaints about

Plants have developed complex molecular mechanisms to recognize and respond to the different microorganisms present in their surroundings. The most studied response mechanisms are plant defense responses. These defense response mechanisms share many similar components with the plant response mechanisms to beneficial microbes. Therefore, studying the defense response mechanisms against pathogens caPlants have developed complex molecular mechanisms to recognize and respond to the different microorganisms present in their surroundings. The most studied response mechanisms are plant defense responses. These defense response mechanisms share many similar components with the plant response mechanisms to beneficial microbes. Therefore, studying the defense response mechanisms against pathogens ca

Background: A large number of individuals with Alzheimer’s disease (AD) live alone and receive little or no help from family members, which implies an additional pressure on the increasing societal costs of dementia care. Their adult children, if any, might have very limited ability to assist by providing informal help because of social structural changes, such as full-time work for most women and

The disruption of microtubule dynamics serves as a pivotal strategy for eliminating tumor cells, despite its accompanying toxicities affecting non-tumor cells. This study investigates the potential of selectively targeting γ-tubulin1 (TUBG1) as a therapeutic strategy in cancer treatment. By elucidating the TUBG1-E2F1-retinoblastoma protein (RB1) network, we introduce a novel compound, 4-(6-((3-Met

Vilken betydelse har det förvetenskapliga för vetenskapen? Vilka betydelser kan det ha? Ska vi som forskare eftersträva största möjliga vetenskaplighet från början till slut? Annorlunda uttryckt: Ska vi metodiskt trycka bort våra förvetenskapliga impulser? Eller ska vi tvärtom välkomna dem? Att följa varje förvetenskaplig impuls, var vi än befinner oss i forskningsprocessen, skulle förmodligen få

Nanotechnology gives us materials with enhanced or completely new properties. At the same time, inhalation of manufactured nano-objects has been related to an array of adverse biological effects. We characterized particle emissions, which occurred during maintenance of common metal nanoparticle generators and contrasted the properties of the emitted particles with those originally produced by the

The article highlights some findings from my research on reconciliation in South Africa and Northern Ireland and sets these findings in relation to the life and work of the famous white South African Dutch Reformed anti-apartheid activist Dr. Beyers Naudé.

Artikeln presenterar resultat från en enkätundersökning bland 2000 personer bosatta i Sverige. I enkäten ställdes bland annat frågor om synen på förhållandet mellan naturvetenskap och religion. Resultaten ger vid handen att man uppfattar naturvetenskap och religion som kompletterande varandra, och att denna uppfattning är vanligare med högre utbildning. Uttalade ateister uppfattar i hög utsträckni

ICT changes continuously and we are used to look at IT in a slightly dif-ferent way every year. Things are developed and manufactured to be smaller and faster but few changes are truly technologically revolutionary. Some changes creep up on us as they arrive under cover of previously known technology. Solid State Disks (SSD) is such a technology. The use of SSD is simple enough and for many purpos

Fuel Taxes and the Poor challenges the conventional wisdom that gasoline taxation, an important and much-debated instrument of climate policy, has a disproportionately detrimental effect on poor people. Increased fuel taxes carry the potential to mitigate carbon emissions, reduce congestion, and improve local urban environment. As such, higher gasoline taxes could prove to be a fundamental part of