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Streptococcus pyogenes AP1, a strain of the highly virulent M1 serotype, uses exclusively protein H to bind the complement inhibitor C4b-binding protein (C4BP). We found a strong correlation between the ability of AP1 and its isogenic mutants lacking protein H to inhibit opsonisation with complement C3b and binding of C4BP. C4BP bound to immobilized protein H or AP1 bacteria retained its cofactor

Aims: Fluorescence in situ hybridization (FISH) can be used to reveal several genomic imbalances relevant to proper cancer diagnosis and to the correct treatment regime. However, FISH requires expensive and advanced fluorescence microscopes in addition to expertise in fluorescence microscopy. To determine whether a newly developed dual-colour chromogenic in situ hybridization (CISH) method is a su

Background Little is known about the influence of compliance with neuromuscular training (NMT) on the knee injury rate in football. Aim To evaluate team and player compliance with an NMT programme in adolescent female football and to study the association between compliance and acute knee injury rates. Methods Prospective cohort study based on a cluster randomised controlled trial on players aged

Sensory nerve desensitization by capsaicin has been shown to improve the diabetic condition in Zucker Diabetic Fatty rats. However, administration of capsaicin to adult rats is associated with an increased mortality. Therefore, in this experiment, we examined the influence of resiniferatoxin, a tolerable analogue of capsaicin suitable for in vivo use, on the diabetic condition of Zucker Diabetic F

Lipoteichoic acid from Staphylococcus aureus was a potent inducer of procoagulant activity in isolated mononuclear cells but not in whole blood. In contrast, staphylococcal peptidoglycan showed equal levels of potency in isolated mononuclear cells and whole blood, suggesting that peptidoglycan is an important inducer of procoagulant activity in severe sepsis involving gram-positive bacteria.

Human immunodeficiency virus type 1-based lentivirus vectors containing the green fluorescent protein (GFP) gene were used to transduce murine Lin(-) c-kit(+) Sca1(+) primitive hematopoietic progenitor cells. Following transduction, the cells were plated into hematopoietic progenitor cell assays in methylcellulose and the colonies were scored for GFP positivity. After incubation for 20 h, lentivir

Understanding the coupling of nitrogen (N) and carbon (C) cycles of land ecosystems requires understanding microbial element use efficiencies of soil organic matter (SOM) decomposition. Whereas important controls of those efficiencies by microbial community adaptations have been shown at the scale of a soil pore, a simplified representation of those controls is needed at the ecosystem scale. Howev

Aims: Our aim was to investigate the impact of intravenous (IV) beta-blocker therapy on short-term mortality and other in-hospital events in patients with ST-segment elevation myocardial infarction (STEMI) treated with dual antiplatelet therapy (DAPT) and primary percutaneous coronary intervention (PCI). Methods and results: Using the nationwide Swedish Web-system for Enhancement and Development o

BackgroundObservational data suggests that an anterior or apical left ventricular (LV) position in Cardiac Resynchronization Therapy (CRT) is associated with worse outcome and higher likelihood of “non-response”. It is not known whether the benefits of optimizing LV lead position in a second procedure outweighs the procedural risks.ObjectiveTo evaluate the clinical effects of LV lead repositioning

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https://www.webbpublicering.lu.se/sites/webbpublicering.lu.se/files/2025-03/BILDGUIDE%201.0.pdf - 2026-07-02

https://www.aclu.lu.se/sites/aclu.lu.se/files/2023-04/DSA.pdf - 2026-07-02

Centrum för handelsforskning vid Lunds universitet VERKSAMHETSBERÄTTELSE | 2024 2 VERKSAMHETSBERÄTTELSE CENTRUM FÖR HANDELSFORSKNING 2024 3 VERKSAMHETSBERÄTTELSE CENTRUM FÖR HANDELSFORSKNING 2024 Introduktion Centrum för handelsforskning - 2024 det sista kapitlet Detta är den 11:e årsrapporten från Centrum för handels- forskning vid Lunds universitet. Det är också den sista års- rapporten vi skriv

https://www.lusem.lu.se/sites/lusem.lu.se/files/2025-05/Centrum%20fo%CC%88r%20handelsforskning%20verksamhetsbera%CC%88ttelse%202024%20slutlig%20webb.pdf - 2026-07-02

1 Lärande i LTH Lunds Tekniska Högskolas pedagogiska akademi och kompetensgraden Excellent Teaching practitioner (ETP) inleder detta nummer av Lärande i LTH. En sammanställning av hur många lärare som erhållit ETP följs av en presentation av årets ETP-utnämningar. Enkäten Course Experience Questionnaire (CEQ) används vid LTH som ett verktyg för rapporterande kursutvärdering. CEQ-resultatet för en

https://www.lth.se/fileadmin/cee/genombrottet/Laerande_i_LTH/Laerande_i_LTH_blad_14.pdf - 2026-06-09

Background: Peripheral blood eosinophilia and lung mucosal eosinophil infiltration are hallmarks of bronchial asthma. IL-5 is a critical cytokine for eosinophil maturation, survival, and mobilization. Attempts to target eosinophils for the treatment of asthma by means of IL-5 neutralization have only resulted in partial removal of airway eosinophils, and this warrants the development of more effec

The discussion of the transition to farming in southern Africa and the formation of Early Iron Age society, referred to in Mozambican archaeology as the Early Farming Communities (EFC), is complicated by the lack of surveys in key areas of intensive contacts. This article presents the results of excavations at the EFC site Chicumbane in the eastern lower Limpopo Valley, dated 500–800 AD. The varia

Following World War Two emigration from Central and Eastern Europe, in particular, has grown in spite of increasingly strict border controls. Given this rise in migration pressure from the East during a strictly regulated period, the 2004 EU enlargement of Cyprus, Czech Republic, Estonia, Hungary, Latvia, Lithuania, Malta, Poland, Slovakia, and Slovenia threatened to transform the migration landsc