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A Biological Signature for Breast Ductal Carcinoma In Situ to Predict Radiotherapy Benefit and Assess Recurrence Risk

PURPOSE: Ductal carcinoma in situ (DCIS) patients and their physicians currently face challenging treatment decisions with limited information about the individual's subsequent breast cancer risk or treatment benefit. The DCISionRT biological signature developed in this study provides recurrence risk and predicts radiotherapy (RT) benefit for DCIS patients following breast-conserving surgery (BCS)

Randomized study on adjuvant chemotherapy in stage I high-risk ovarian cancer with evaluation of DNA-ploidy as prognostic instrument

PURPOSE: Adjuvant chemotherapy versus observation and chemotherapy at progression was evaluated in 162 patients in a prospective randomized multicenter study. We also evaluated DNA-measurements as an additional prognostic factor.PATIENTS AND METHODS: Patients received adjuvant carboplatin AUC 7 every 28 days for six courses (n = 81) or no adjuvant treatment (n = 81). Eligibility included surgicall

Governing Decarbonisation : The State and the New Politics of Climate Change

This dissertation examines the “new climate politics of decarbonisation” and the role of the state as a site for progressive climate action. This new politics concerns transformative social change aimed at moving society away from its current dependence on fossil carbon energy. A transition to low-carbon societal development hinges on restructuring and decarbonising those key systems, structures a

Analysis of Brain Injury Biomarker Neurofilament Light and Neurodevelopmental Outcomes and Retinopathy of Prematurity among Preterm Infants

Importance: Circulating levels of neurofilament light (NfL) and glial fibrillary acidic protein (GFAP) are important in the course of brain injury in adults, but longitudinal postnatal circulating levels in preterm infants have not been investigated. Objectives: To examine postnatal longitudinal serum levels of NfL and GFAP in preterm infants during the first 15 weeks of life and to explore possib

ErbB2 status and the benefit from two or five years of adjuvant tamoxifen in postmenopausal early stage breast cancer

AIM: We aimed to study the importance of erbB2 status in early stage postmenopausal breast cancer for patients who participated in a trial of five vs. two years of adjuvant tamoxifen.PATIENTS AND METHODS: We analysed the erbB2 status of the tumours from 577 patients participating in the trial, either by a DNA amplification assay (n = 181) or by measurement of the protein level with flow cytometry

Cognitive functioning in adolescents with severe obesity undergoing bariatric surgery or intensive non-surgical treatment in Sweden (AMOS2): a multicentre, open-label, randomised controlled trial

Severe obesity during childhood is associated with cognitive deficits. Studies in adults have suggested improvements in executive functioning and memory after bariatric surgery. Our aim was to explore changes in cognitive function in adolescents over two years after bariatric surgery or intensive non-surgical treatment. Methods: The Adolescent Morbid Obesity Surgery 2 (AMOS2) is a multicentre, ope

Integrating Tumor-Intrinsic and Immunologic Factors to Identify Immunogenic Breast Cancers from a Low-Risk Cohort : Results from the Randomized SweBCG91RT Trial

PURPOSE: The local immune infiltrate's influence on tumor progression may be closely linked to tumor-intrinsic factors. The study aimed to investigate whether integrating immunologic and tumor-intrinsic factors can identify patients from a low-risk cohort who may be candidates for radiotherapy (RT) de-escalation.EXPERIMENTAL DESIGN: The SweBCG91RT trial included 1,178 patients with stage I to IIA

Communicating science through competing logics and a science-art lens

This essay takes a starting point in the well-known tension between the media logic and the scientific logic and the challenges when communicating science in a mediatized society. Building on the experience of engaging in research comics, both as a method for communicating science and a creative example of a meeting between science and art, we introduce a framework — a pedagogical tool — for how s

Perioperative systemic chemotherapy in peritoneal carcinomatosis of lymph node positive colorectal cancer treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

BACKGROUND: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) is the preferred treatment of peritoneal carcinomatosis (PC) of colorectal carcinoma. Patients with positive lymph node status have worse survival after CRS-HIPEC, which is probably due to higher rates of systemic failure. In this study, we analysed the effect of administration and timing of systemic chemot

Multiple Forms of Endocannabinoid and Endovanilloid Signaling Regulate the Tonic Control of GABA Release

UNLABELLED: Persistent CB1 cannabinoid receptor activity limits neurotransmitter release at various synapses throughout the brain. However, it is not fully understood how constitutively active CB1 receptors, tonic endocannabinoid signaling, and its regulation by multiple serine hydrolases contribute to the synapse-specific calibration of neurotransmitter release probability. To address this questi

Entinostat Enhances the Efficacy of Chemotherapy in Small Cell Lung Cancer Through S-phase Arrest and Decreased Base Excision Repair

PURPOSE: Acquired chemoresistance is a frequent event in small cell lung cancer (SCLC), one of the deadliest human malignancies. Histone deacetylase inhibitors (HDACi) have been shown to synergize with different chemotherapeutic agents including cisplatin. Accordingly, we aimed to investigate the dual targeting of HDAC inhibition and chemotherapy in SCLC.EXPERIMENTAL DESIGN: The efficacy of HDACi

Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function

A major challenge in neuroscience is to resolve the connection between gene functionality, neuronal circuits, and behavior. Most, if not all, neuronal circuits of the adult brain contain a glutamatergic component, the nature of which has been difficult to assess because of the vast cellular abundance of glutamate. In this study, we wanted to determine the role of a restricted subpopulation of glut

The age-dependent association of risk factors with pancreatic cancer

BACKGROUND: Pancreatic cancer presents as advanced disease in >80% of patients; yet, appropriate ages to consider prevention and early detection strategies are poorly defined. We investigated age-specific associations and attributable risks of pancreatic cancer for established modifiable and non-modifiable risk factors.PATIENTS AND METHODS: We included 167 483 participants from two prospective US

Vad-hande-sedan

Vad hände sedan? EN ALUMNUNDERSÖKNING AV STATSVETARE I YRKESLIVET 2 SLUTRAPPORT ALUMNEKÄT 2013 3SLUTRAPPORT ALUMNEKÄT 2013 1. Inledning Statsvetenskapliga institutionen inledde för några år sedan ett arbete med att synliggöra sambandet mellan våra utbildningar och studen- ternas framtida yrkesliv. Vi har på relativt kort tid byggt upp en av de största alumndatabaserna vid Lunds universitet, utveck

https://www.svet.lu.se/sites/svet.lu.se/files/vad-hande-sedan.pdf - 2026-05-14

Råd Och Anvisningar 2025

Råd och anvisningar för uppsatsarbete Socialhögskolan vid Lunds universitet September 2025 Förord Arbetet med Råd och anvisningar för uppsatsarbete inleddes av Katarina Jacobsson, som var huvudansvarig för den första upplagan (2008) och därefter höll i den löpande översynen. Den första upplagan byggde bland annat vidare på tidigare uppsatsanvisningar och grunder för bedömningskriterier formulerade

https://www.soch.lu.se/sites/soch.lu.se/files/2025-09/R%C3%A5d%20och%20anvisningar%202025.pdf - 2026-05-14

LAMiNATE Talks

LAMiNATE Talks | Språk- och litteraturcentrum LAMiNATE Talks Rss-flöde Händelsetyp Alla händelser Seminarium Händelser per termin Välj termin vårterminen 2025 höstterminen 2025 vårterminen 2026 26 maj 26 maj 2026 15:15 till 16:30 Seminarium LAMiNATE Talks: Gesa Hartwigsen — Flexible Adaptation of Language Processing Under Challenge 9 jun 9 juni 2026 15:15 till 16:30 Seminarium LAMiNATE Talks: Wand

https://www.sol.lu.se/institutionen/kalendarium/seminarieserier/LAMiNATE+Talks/ - 2026-05-14

Brevmall

Brevmall FIVL01, Film och audiovisuella medier för gymnasielärare (3 hp) Litteraturlista ST2021 (Fastställd i Sektionsstyrelse 2, SOL-Centrum, 11 Maj 2021) Andersen, Neil (2014). ”Media Literacy Education in Ontario”. Ingår i: Belinha De Abreu & Paul Mihailidis (red.), Media literacy education in action: theoretical and pedagogical perspectives, New York: Routledge, s. 20-26. (7 s.) BFI (2015), ”A

https://www.sol.lu.se/media/utbildning/dokument/kurser/FIVL01/20211/FIVL01._ST21._Litteraturlista_2_.pdf - 2026-05-11