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Digital healthcare services and digital health information, here called eHealth services, have the potential to reach people with diverse needs as both a complement to and a substitution for traditional healthcare. The access to and use of digital health information and digital healthcare services that are accessible and usable for people with impairments is a complex phenomenon.This potential is
BACKGROUND: Coronary atherosclerosis detected by imaging is a marker of elevated cardiovascular risk. However, imaging involves large resources and exposure to radiation. The aim was, therefore, to test whether nonimaging data, specifically data that can be self-reported, could be used to identify individuals with moderate to severe coronary atherosclerosis.METHODS AND RESULTS: We used data from t
Contemporary society operates beyond safe boundaries of the Earth system. Returning to a safe operating space for humanity within Earth system boundaries is a question of justice. The relevance of the economy—and thus of business—for bringing society back to a safe and just operating space highlights the importance of business ethics research for understanding the role of business in Earth system
Livscykelanalys (LCA) används för att utvärdera den potentiella miljöpåverkan av olika processer och tjänster, bland annat inom bygg- och fastighetssektorerna. Denna studie jämför tre LCA-verktyg som är speciellt utvecklade för användning inom bygg- och fastighetssektorn mot ett fjärde som är ett allmänt LCA-verktyg. En LCA görs för en fallstudie av ett flerfamiljshus där ett ventilationssystem meLife cycle assessment (LCA) is used to evaluate the potential environmental impact of different processes and services, including in the construction and real estate sectors. This study compares three LCA tools that have been specifically developed for use in the construction and real estate sectors with a fourth that is a general LCA tool. An LCA is performed for a case study of a multi-family bu
The article presents an analysis of boundary work within the context of care for the elderly, where violence appears to be widespread though still relatively unacknowledged. By resorting to certain descriptive – often jocular – modes, the staff designate aggressive acts committed by patients as 'non-violent'. This occurs although intent, responsibility, and injury – all common criteria associated
To assess the role of CHCHD2 variants in patients with Parkinson disease (PD) and Lewy body disease (LBD) in Caucasian populations.
Popular Abstract in Swedish Tillväxtfaktorer påverkar signaler mellan celler i hjärnan Människors hjärnor innehåller flera miljarder hjärnceller, vilka är förutsättningen för vårt beteende, våra känslor och våra tankar. Hjärncellerna bildar kontakter, synapser, med varandra. Genom dessa överförs signaler från en cell till en annan. Varje cell kontaktar en mängd andra celler, både sådana med liknanThe neurotrophins, notably brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT3), modulate synaptic transmission and synaptic plasticity in the adult mammalian brain. Recent data suggest that neurotrophins might be mediators of activity-dependent synaptic plasticity. Such plasticity is believed to be a cellular correlate for important processes like learning, but also for diseases, for
BACKGROUND: Maternally derived duplications of the 15q11-q13 region are the most frequently reported chromosomal aberrations in autism spectrum disorders (ASD).Prader-Willi and Angelman syndromes, caused by 15q11-q13 deletions or abnormal methylation of imprinted genes, are also associated with ASD. However, the prevalence of these disorders in ASD is unknown. The aim of this study was to assess t
Computers are increasingly used for implementing controlalgorithms in safety-critical embedded applications, such asengine control, braking control and flight surfacecontrol. Addressing the consequent coupling of control performancewith computer related errors, this paper develops a composite computerdependability/control theory methodology for analyzing the effectsdata errors have on control syst
Lung transplantation is the only option for patients with end-stage lung disease, but there is a shortage of available lung donors. Furthermore, efficiency of lung transplantation has been limited due to primary graft dysfunction. Recent mouse models mimicking lung disease in humans have allowed for deepening our understanding of disease pathomechanisms. Moreover, new techniques such as decellular
Savannas are inherently “disturbed” ecosystems, but the regularly recurring disruptions play such a fundamental ecological role (Scholes and Archer, 1997) that “episodic events” rather than “disturbance” may the more apt terminology. From an atmospheric perspective, fire is the most significant of these episodic events. Fires shape community species composition; tree to grass ratio and nutrient re
Ferromagnetic semiconductor thin layers of the quaternary (Ga,Mn)(Bi,As) and reference, ternary (Ga,Mn)As compounds, epitaxially grown under either compressive or tensile strain, have been characterized from a perspective of structural and magnetization homogeneity. The quality and composition of the layers have been confirmed by secondary-ion mass spectrometry (SIMS). A thorough evaluation of the
The Baltic Sea is one of the most eutrophied seas in the world, facing challenges with both hypoxia and algae blooms. In this study we analyse the effect of using different fishery policy instruments to reduce nutrient loads by removing fish biomass from the ecosystem. The study covers Danish, Finnish and Swedish pelagic fisheries. We distinguish between a private optimum maximising the net presen
