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Oncogenic c-Kit mutations have been shown to display ligand-independent receptor activation and cell proliferation. A substitution of aspartate to valine at amino acid 816 (D816V) is one of the most commonly found oncogenic c-Kit mutations and is found in >90% of cases of mastocytosis and less commonly in germ-cell tumors, core-binding factor acute myeloid leukemia and mucosal melanomas. The mecha

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Rare earth elements comprise the metallic elements known as lanthanides as well as scandium and yttrium. They are extensively used in modern technological industries and are considered as strategic commodities in many countries. Rare earth element minerals with varying compositions are found at deposits throughout the world, though most of the global REE supply comes from only a few sources. The cRare earth elements comprise the metallic elements known as lanthanides as well as scandium and yttrium. They are extensively used in modern technological industries and are considered as strategic commodities in many countries. Rare earth element minerals with varying compositions are found at deposits throughout the world, though most of the global REE supply comes from only a few sources. The c

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Brain-derived neurotrophic factor (BDNF) is an important protein for neuroplasticity and neurogenesis. In this thesis the role of BDNF, in suicidal behaviour was investigated with focus on possible risk factors for suicidal behaviour such as avoidant focused coping, dysfuntional personality traits like impulsiveness and hyperactivity of the Hypothalamic-Pituitary-Adrenal (HPA) axis.Paper I: The a

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After authoritarian periods of human rights abuses by the state, trust in state institutions is likely to have eroded among most citizens. One way to try to re-establish this trust - which many researchers believe is essential to make democracy work - is to hold those responsible accountable in criminal trials. But to what extent do such trials affect public confidence, and how does the role of tr

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Enzymes play a key role in almost all biological processes, accelerating a variety of metabolic reactions as well as controlling energy transduction, the transcription, and translation of genetic information, and signaling. They possess the remarkable capacity to accelerate reactions by many orders of magnitude compared to their uncatalyzed counterparts, making feasible crucial processes that woul

Preliminart mven15 schema ht18

PRELIMINÄRT_MVEN15_schema_ht18.xlsx Prel.Schema MVEN015 - Klimatförändringen - vetenskap och samhälle Höstterminen 2018 OBS Alla starttider med kvart utom tentamen! Kurstid: - Kurschef: Niklas Vareman Lärare: GZ Giuliana Zanchi MLL Maj-Lena Linderson JS Johannes Stripple NV Niklas Vareman JAO Johanna Alkan Olsson DHa Dan Hammarlund DH David Harnesk Salar: Litteratur: - Houghton, J. T. 2015: Global

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/preliminart_mven15_schema_ht18.pdf - 2026-07-22

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Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei