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A Broad Survey and Functional Analysis of Immunoglobulin Loci Variation in Rhesus Macaques

Rhesus macaques (RMs) are a vital model for studying human disease and invaluable to pre-clinical vaccine research, particularly for the study of broadly neutralizing antibody responses. Such studies require robust genetic resources for antibody-encoding genes within the immunoglobulin (IG) loci. The complexity of the IG loci has historically made them challenging to characterize accurately. To ad

A core outcome set for best care for the dying person : Results of an international Delphi study and consensus meeting

Background: Outcome measurement is essential to progress clinical practice and improve patient care. Aim: To develop a Core Outcome Set for best care for the dying person. Design: We followed the Core Outcome Measures in Effectiveness Trials (COMET) Initiative guidelines, which involved identifying potential outcomes via a systematic literature review (n = 619 papers) and from participants in the

Multi-pass Cell Based Nonlinear Pulse Compression of Yb : YAG Pump-Probe Lasers at FLASH

The majority of user experiments at the high repetition-rate free electron laser (FEL) facility FLASH are of pump-probe type, combining the extreme ultraviolet (XUV) or soft x-ray radiation from the FEL with ultrashort pulses generated by optical lasers. In this contribution, we demonstrate the advantages of using high-power Yb:YAG lasers with subsequent nonlinear pulse compression stages based on

p53-mediated differentiation of the erythroleukemia cell line K562

The tumor suppressor gene p53 can mediate both apoptosis and cell cycle arrest. In addition, p53 also influences differentiation. To further characterize the differentiation inducing properties of p53, we overexpressed a temperature-inducible p53 mutant (ptsp53Val135) in the erythroleukemia cell line K562. The results show that wild-type p53 and hemin synergistically induce erythroid differentiati

RIFM fragrance ingredient safety assessment, dihydrocarvyl acetate, CAS Registry Number 20777-49-5

The existing information supports the use of this material as described in this safety assessment. Dihydrocarvyl acetate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analogs dihydrocarveol (isomer unspecified) (CAS # 619-01-2) and aceti

Progress on laser-driven X-ray sources at ELI Beamlines

Three main paths are being developed within the ELI research program for transforming driving laser pulses into bursts of bright short wavelength radiation: high-order harmonic generation in gases, plasma X-ray sources and sources based on relativistic electron beams accelerated in laser plasma. For each of these research areas, dedicated beamlines are built to provide a unique combination of X-ra

Developing ultrasound optical tomography for deep tissue imaging of the breast

Ultrasound Optical Tomography (UOT) combines the high-resolution imaging capability of ultrasound with measurements of light absorption and scattering properties of human tissue. This non-invasive technique could distinguish between cancerous and non-cancerous lesions inside the breast tissue, follow tumor shrinkage during preoperative treatment, or provide information on blood oxygenation levels.

Attohallen – a new attosecond science facility in Sweden

We present the concept of our new high power laser facility Attohallen in Gothenburg, with focus on its first high-order harmonic generation beam line. The key specifications of this facility, including the architecture and operation of the femtosecond drive laser system, the XUV generation part of its first beam line for photon-demanding attosecond timing experiments in the energy range up to abo

Vbe johannes

SCIENCE AND PROVEN EXPERIENCE JOHANNES VETENSKAP OCH BEPRÖVAD ERFARENHET VID SBU | 1 2 | STEN ANTTILA & SUSANNA AXELSSON SCIENCE AND PROVEN EXPERIENCE JOHANNES ISBN 978-91-983575-5-4 © The VBE Research Program and the Authors Graphic design Johan Laserna Printed by Media-Tryck, Lund University, Lund 2018 Preface 9 NILS-ERIC SAHLIN A note on randomized controlled trials in evidence-based medicine 1

https://www.vbe.lu.se/sites/vbe.lu.se/files/vbe_johannes.pdf - 2026-05-07

Conference Abstracts 2024

1 CONFERENCE ABSTRACTS Lund University Research Conference KNOWLEDGE FOR SUSTAINABLE DEVELOPMENT 4 DECEMBER 2024 | STADSHALLEN, LUND Session I - 11:00-11:30 - I Regulation, policy and responsibility - II Empowering people and organizations - III People at risk - IV Navigating global networks and circular economy Session II – 14:55-15:55 - I Natural resources - controversies and redefinitions - II

https://www.sustainability.lu.se/sites/sustainability.lu.se/files/2024-12/Conference%20abstracts%202024.pdf - 2026-05-07