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A majority of the established systems for determination and optimization of cutting data are based on Woxén’s equivalent chip thickness, heW. In metal cutting theory and models, the equivalent chip thickness is of vital importance when the depth-of-cut ap is in the same order or smaller than the nose radius r. Woxén made considerable simplifications in his chip area model, that form the basis for
To evaluate the cost-effectiveness of an additional 12-week treatment with varenicline for abstainers who had successfully completed an initial 12-week treatment. The Benefits of Smoking Cessation on Outcomes simulation model was used to simulate both direct and indirect effects of smoking cessation. All calculations were performed in 2003 Swedish prices. Sweden in 2003. The modelled cohort consis
To further develop and evaluate a pharmacophore model previously proposed by Cook and co-workers (Drug Des. Discovery 1995,12,193-248) for ligands binding to the benzodiazepine site of the GABA(A) receptor, 40 new flavone derivatives have been synthesized and their affinities for the benzodiazepine site have been determined. Two new regions of steric repulsive interactions between ligand and recep
Context. The stellar abundance ratio of Mg/Fe is an important tool in diagnostics of galaxy evolution. In order to make reliable measurements of the Mg abundance of stars, it is necessary to have accurate values for the oscillator strength (f- value) of each of the observable transitions. In metal-poor stars the MgI 3p-4s triplet around 5175 angstrom (Fraunhofer's so-called b lines) are the most p
The impact of warmer climate on melt and evaporation was studied for tainted, snowfed and glacierfed basins located in the western Himalayan region. Hydrological processes were simulated under current climatic conditions using a conceptual hydrological model, which accounts for the rainfall-runoff, evaporation losses, snow and glacier melt. After simulations of daily observed strearnflow (R-2 = 0.
DELPHI data collected at centre-of-mass energies up to 208 GeV have been analysed to search for charginos, neutralinos and sfermions in the framework of the Minimal Supersymmetric Standard Model (MSSM) with R-parity conservation. No evidence for a signal was found in any of the channels. The results of each search were used to derive limits on production cross-sections and particle masses. In addi
Ion current measurements can give information useful for controlling the combustion stability in a multi-cylinder engine. Operation near the dilution limit (air or EGR) can be achieved and it can be optimized individually for the cylinders, resulting in a system with better engine stability for highly diluted mixtures. This method will also compensate for engine wear, e.g., changes in volumetric e
Recombinant cystatin C producing clones were isolated from a human placenta λgt11 cDNA library. The cDNA insert of one of the clones, containing 777 base pairs, encodes the complete mature cystatin C (120 amino acids) and a hydrophobic leader sequence of 26 amino acids, indicating an extracellular function of the inhibitor. The deduced protein sequence confirms the protein sequence of cystatin C i
In this study the integration and optimisation of hydrophobic pervaporation for the recovery of natural aroma compounds in the food industry has been studied. The simulation developed in the first part of this study was applied to the design and scale-up of pervaporation units for the recovery of natural apple juice aroma. Both semi-batch and continuous process configurations were considered and t
Objective: To examine the intertester reliability of the three activities of the Cumulated Ambulation Score (CAS) and the total CAS, and to define limits for the smallest change in basic mobility that indicates a real change in patients with hip fracture.Design: An intertester reliability study.Setting: An acute 20-bed orthopaedic hip fracture unit.Subjects: Fifty consecutive patients with a media
OBJECTIVES: The soluble epoxide hydrolase (gene name EPHX2) is responsible for metabolism of 8,9 11,12 and 14,15-epoxyeicosatrienoic acids, vasodilator and anti-inflammatory substances. There are several functional polymorphisms in the EPHX2 gene: two of them, the K55R and R287Q, showing an altered metabolic activity in vitro, were associated with coronary heart disease and ischemic stroke in prev
BACKGROUND: The aim of this study was to examine potential therapeutic effect of the two NO donors NCX 2057 (3-(4-hydroxy-3-methoxyphenyl)-2-propenoic acid) 4-(nitrooxy)butyl ester) and SNP (sodium nitroprusside) on the early allergic airway response in the peripheral lung. METHODS: The experiments were performed in guinea pig lung parenchyma (GPLP) derived from ovalbumin (OVA) sensitized guinea p
Vacuum-assisted wound closure (VAC) therapy may heal wounds faster than conventional dressings after surgical debridement of perivascular groin infections after vascular surgery.
A search is presented for heavy-quark pair production (Q (Q) over bar) under the decay hypothesis Q (Q) over bar -> W(+)qW(-)(q) over bar with q = d, s, b for up-type Q or q = u, c for down-type Q. The search is performed with 1.04 fb(-1) of integrated luminosity from pp collisions at root s = 7 TeV collected by the ATLAS detector at the CERN LHC. Dilepton final states are selected, requiring larg
The aim of this study was 1) to investigate interfraction set-up uncertainties for patients treated with respiratory gating for left-sided breast cancer, 2) to investigate the effect of the inter-fraction set-up on the absorbed dose-distribution for the target and organs at risk (OARs) and 3) optimize the set-up correction strategy. By acquiring multiple set-up images the systematic set-up deviati
Based on morphological analyses, extant members of the order Crocodylia are divided into three families, Alligatoridae, Crocodylidae, and Gavialidae. Gavialidae includes one species, the gharial, Gavialis gangeticus. In this study we have examined crocodilian relationships in phylogenetic analyses of seven mitochondrial genomes that have been sequenced in their entirety. The analyses did not suppo
