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INTRODUCTION: Biomarkers play a crucial role in understanding Alzheimer's disease (AD) pathogenesis and treatment effects. However, comparing biomarker measures without standardization and appreciating their magnitude relative to the disease can be challenging. METHODS: To address this issue, we propose the CentiMarker approach, similar to Centiloid, which provides a standardized scale between nor
The exponential increase in medical waste production has increased the difficulty of waste management, resulting in higher medical waste dispersion into the environment. By employing a circular economy approach, it is possible to develop new materials by waste valorization. The employment of biodegradable and renewable agro-food, waste-derived materials may reduce the environmental impact caused b
The present study investigates the integration of Lean and Sustainable manufacturing (LSM) practices to improve the market competitiveness of Indian manufacturing organizations. The study aims to explore the critical role of stakeholder commitment to drive both sustainable manufacturing and lean practices with their impact on manufacturing competitiveness. In the study a survey-based approach was
Bakgrund: Den kurativa behandlingen för resektabla lokalt avancerade stadier av cancer i munhålan innefattar i regel en kombination av kirurgi och radioterapi (RT). Huruvida RT bör ges först och därefter följas av kirurgi, eller om tumören bör opereras bort först, följt av RT postoperativt, har dock inte studerats i någon större omfattning.Syfte: Denna avhandling undersöker olika aspekter av pre- Background: The curatively intended treatment for resectable locally advanced stages of oral cavity cancer (OCC) generally involves a combination of surgery and radiotherapy (RT). However, whether to apply RT first and then proceed with surgery, or to resect the cancer and subsequently administer RT, has not been extensively studied. Aims: This thesis examines various aspects of pre- versus postop
A diagonalisation procedure of the Foldy-Wouthuysen type is considered for the single-electron Dirac Hamiltonian as a basis for many-body applications. A modified procedure is suggested. In the diagonalisation procedure the Dirac equation is completely decoupled into two equations of the Pauli type. The expressions for positive- and negative-energy projection operators in the transformed basis are
Timber’s sustainability benefits make it an attractive construction material, but public concerns about fire safety remain a challenge. Many associate timber buildings with higher fire risks, particularly in taller structures, despite trusting regulations and professionals to ensure safety. This highlights a gap between public perception and technical knowledge. Designers have a professional respo
The power take-off (PTO) system and control laws for wave energy converters (WECs) are crucial for system performance. Determining optimal PTO parameters based on different sea states is key for formulating control laws, identifying optimal WEC locations, and optimizing wave-to-wire performance. This study focuses on an oscillating water column (OWC) type WEC developed by Waves4Power using a buoy
This chapter explores the interaction between competition law and especially Article 101(3) TFEU and environmental and climate change goals in the context of the EU’s Green Deal and the aim of energy transition. First, it reviews the evolution of the Commission’s and national authorities’ approaches to environmental and climate benefits in their general assessment of horizontal and vertical agreem
Lagging fires, also known as insulation fires, pose significant risks in the process industry, arising from the self-heating of leaked combustible liquids within insulation materials. These fires typically initiate through oxidation, leading to smouldering that can escalate into larger fires or serve as ignition sources for other flammable materials. Statistics from the Swedish Contingency Agency
Background: Levodopa–entacapone–carbidopa intestinal gel (LECIG) was introduced on the Swedish market in 2019. The therapy is aimed at patients with Parkinson's disease (PD) with fluctuations and dyskinesias. Long-term efficacy and safety data are lacking. Objective: To investigate the efficacy, tolerability, and safety of LECIG in regular clinical practice for Parkinson's disease in Sweden. Metho
Recent scholarship in critical intelligence studies emphasizes the role of informal actors in democratic oversight, encouraging increased attention to practices and struggles of accountability. Less probed are the fundamental conditions enabling the work of informal oversight actors, and current struggles over such conditions. This article turns to the case of Sweden, a top-ranking state in the pr
This conceptual article examines the relational dynamic between the research field focusing on the far right and those critical scholars that endeavour to undertake these studies. It is theoretically anchored in the field of political science scholarship that recognises the key role played by gender in understanding both the ideological underpinnings and the workings of various far-right entities
It is well known that Lithium-ion batteries in thermal runaway can emit gases with high hydrogen concentrations which, in case of delayed ignition, can cause a gas explosion. Aerosol suppression agents are sometimes used to suppress fires and/or prevent ignition of released gases in such situations. The agent has been studied for suppression of fires (diffusion flames), but less is known about the
Due to increasing plastic production, the continuous release of primary and secondary nanoplastic particles (NPs, <1 μm) has become an emerging contaminant in terrestrial environments. The fate and transport of NPs in subsurface environments remain poorly understood, largely due to the complex interplay of mineralogical, chemical, biological, and morphological heterogeneity. This study examines in
Aim: The aim of this study was to explore the role of managers and employees with an assigned responsibility (i.e. inspirers) when integrating recovery-enhancing activities into everyday work in a primary health care setting. Background: The possibility of recovery during the workday is essential for employee wellbeing. However, the literature on workplace interventions focusing on recovery is sca
However, it is not clear to what extent corresponding perceptual preferences for intonational deviations might rely on listeners’ instrumental expertise or such contextual aspects as the metrical placement of tones. We investigated higher-education music students’ perceptual preferences for melodic intonation of local leading tones in unaccompanied classical violin performances. Recordings of 12 e
