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Objective: To validate a prediction model for successful vaginal birth after Cesarean delivery (VBAC) based on sonographic assessment of the hysterotomy scar, in a Swedish population. Methods: Data were collected from a prospective cohort study. We recruited non-pregnant women aged 18–35 years who had undergone one previous low-transverse Cesarean delivery at ≥ 37 gestational weeks and had had no

Background: Earlier attempts to deliver effective lung doses of surfactant by aerosolization were unsuccessful, mostly because of technical shortcomings. We aimed at quantifying the lung deposition of poractant alfa with a new supraglottic delivery system for surfactant atomization in an experimental neonatal model. Methods: The method involved six sedated 1-day-old piglets lying in the lateral de

This study evaluated the safety and tolerability of ocular RS1 adeno-associated virus (AAV8-RS1) gene augmentation therapy to the retina of participants with X-linked retinoschisis (XLRS). XLRS is a monogenic trait affecting only males, caused by mutations in the RS1 gene. Retinoschisin protein is secreted principally in the outer retina, and its absence results in retinal cavities, synaptic dysfu

Encapsulation systems have long been studied, and the designs have varied in both capsule material as well as the type of cargo. The intended use have ranged from nanoreactors to delivery systems. This work presents an encapsulation system consisting of protein capsule and a protein cargo. The capsule is a redesigned hepatitis B virus capsid protein, in which the luminal extension has been altered

Growth factors promote plasticity in injured brain and improve impaired functions. For clinical application, efficient approaches for growth factor delivery into the brain are necessary. Poly(ester amide) (PEA)-derived microspheres (MS) could serve as vehicles due to their thermal and mechanical properties, biocompatibility and biodegradability. Vascular endothelial growth factor (VEGF) exerts bot

https://www.iko.lu.se/symposium_animalstudies - 2026-07-17

https://www.iko.lu.se/evenemang/nordic-baltic-symposium-animal-studies-convene-lund-university - 2026-07-17

Collagen VI, a microfibrillar protein found in virtually all connective tissues, is composed of three distinct subunits, alpha 1(VI), alpha 2(VI), and alpha 3(VI), which associate intracellularly to form triple helical heterotrimeric monomers then dimers and tetramers. The secreted tetramers associate end-to-end to form beaded microfibrils. Although the basic steps in assembly and the structure of

Ashbya gossypii is a homothallic, flavinogenic, filamentous ascomycete that starts overproduction of riboflavin and fragments its mycelium quantitatively into spore producing sporangia at the end of a growth phase. Mating is not required for sporulation and the standard homothallic laboratory strain is a MATa strain. Here we show that ectopic expression of Saccharomyces cerevisiae MATα2 in A. goss

This work is to popularize the method of computing the distribution of the excursion times for a Gaussian process that involves extended and multivariate Rice's formula. The approach was used in numerical implementations of the high-dimensional integration routine and in earlier work it was shown that the computations are more effective and thus more precise than those based on Rice expansions.The

Due to their potential environmental risk, the abatement of organic micropollutants from wastewater has gained increasing attention in recent years. This thesis evaluates the use of ozone in Swedish wastewater treatment plants (WWTPs) and the incentives for full-scale implementation of organic micropollutant removal.This work is divided into two sections: the first segment comprises quantitative r

MILJÖVETENSKAP Preliminärt schema 170609 Kurs: MVEN015, Klimatförändringen, vetenskap och samhälle Kursansvarig: Niklas Vareman Lärare: Giuliana Zanchi, Maj-Lena Linderson, Johannes Stripple, Niklas Vareman, Johanna Alkan-Olsson, Dan Hammarlund, David Harnesk Lokaler: Retina (D227) i Biologihuset, Sölvegatan 35, se karta Se karta http://www.biologi.lu.se/sites/biologi.lu.se/files/biologiv2a4.pdf L

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mv15_ht17_v.2.pdf - 2026-07-18