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The association between body mass index and live birth and maternal and perinatal outcomes after in-vitro fertilization : a national cohort study
Objective: To investigate the association between female body mass index (BMI) and live birth rates and maternal and perinatal outcomes after in-vitro fertilization (IVF). Methods: We performed a national, population-based cohort study including women undergoing IVF between 2002 and 2020. The cohort included 126,620 fresh cycles and subsequent frozen embryo transfers between 2007 and 2019 (subpopu
Cumulative live birth rate after IVF : Trend over time and the impact of blastocyst culture and vitrification
STUDY QUESTION: Has cumulative live birth rate (CLBR) improved over time and which factors are associated with such an improvement? SUMMARY ANSWER: During an 11-year period, 2007-2017, CLBR per oocyte aspiration increased significantly, from 27.0% to 36.3%, in parallel with an increase in blastocyst transfer and cryopreservation by vitrification. WHAT IS KNOWN ALREADY: While it has been shown that
Assessment of selection bias due to dropouts in the follow-up of the Scania Public Health Cohort
Aims: To investigate potential differences between participants and dropouts in the 2005 follow-up of the Scania Public Health Cohort Study regarding the prevalence of commonly studied health determinants and whether these factors had differential associations with three health outcomes: all-cause mortality and purchase of prescribed cardiovascular or psychotropic drugs during a 10-year follow-up
A Nationwide Cohort Study of Outcome after Pediatric Appendicitis
Introduction Children with appendicitis often present with complicated disease. The aim of this study was to describe the clinical management of pediatric appendicitis, and to report how disease severity and operative modality are associated with short- and long-term risks of adverse outcome. Materials and Methods A nationwide retrospective cohort study of all Swedish children (<18 years) diagnose
Associations between antenatal and perinatal risk factors and cerebral palsy : a Swedish cohort study
OBJECTIVES: To investigate known and suggested risk factors associated with cerebral palsy in a Swedish birth cohort, stratified by gestational age. SETTING: Information on all births between 1995 and 2014 in Skåne, the southernmost region in Sweden, was extracted from the national birth register. PARTICIPANTS: The cohort comprised a total of 215 217 children. Information on confirmed cerebral pal
Assessing heterogeneous effects and their determinants via estimation of potential outcomes
When analyzing effect heterogeneity, the researcher commonly opts for stratification or a regression model with interactions. While these methods provide valuable insights, their usefulness can be somewhat limited, since they typically fail to take into account heterogeneity with respect to many dimensions simultaneously, or give rise to models with complex appearances. Based on the potential outc
Cerebral palsy in extremely preterm infants
Background and Objectives: The risk of cerebral palsy (CP) is high in preterm infants and is often accompanied by additional neurodevelopmental comorbidities. The present study describes lifetime prevalence of CP in a population-based prospective cohort of children born extremely preterm, including the type and severity of CP and other comorbidities (ie, developmental delay and/or cognitive impair
Application of positive matrix factorization (PMF) to real time aerosol mass spectrometry measurements in an occupied apartment in Sweden
Introduction Given that in developed countries we spend about 65% of our time in private homes (Brasche et al. 2005), understanding the exposures in homes is of outmost importance. Airborne particle concentrations indoors can be affected by particles of indoor and outdoor origins, as well as physico-chemical processes indoors, outdoor infiltration affected by tightness of the building envelope and
Quality of Academic Writing for Engineering Students at Lund University
The development of good writing skills is fundamental not only to publish scientific results, but also to have a deeper understanding of complex subjects. However reports from the Swedish Higher Education Authority from 2012-2015 suggest that engineering students at Lund University have unsatisfactory academic writing skills. Our paper investigates how students of the Faculty of Engineering at Lun
Public engagement in the margin
Phenylation of Platinum(II) Thioether Complexes by Tetraphenylborate(III) in Solid State and Nitromethane Solution
Platinum(II) complexes of the type [Pt(thioether)2Cl]+(thioether = dimethyl sulfide, thioxane) are capable of abstracting a phenyl group from the BPh4 counterion with formation of trans[Pt(thioether)2ClPh] compounds. Thermal reactions proceed both in the solid phase and in nitromethane solution at elevated temperature and have preparative importance. Phenylation of the Pt(II) centre also occurs inPlatinum(II) complexes of the type [Pt(thioether)2Cl]+(thioether = dimethyl sulfide, thioxane) are capable of abstracting a phenyl group from the BPh4 counterion with formation of trans[Pt(thioether)2ClPh] compounds. Thermal reactions proceed both in the solid phase and in nitromethane solution at elevated temperature and have preparative importance. Phenylation of the Pt(II) centre also occurs in
Characteristics of Particulate Emissions from Low Temperature Combustion and Renewable Fuels : Aerosol Mass Spectrometry of Refractory Carbonaceous Particles
Particulate air pollution is one of the major causes of premature death in the world, and combustion-derived soot emissions contribute strongly to the particulate pollution to which humans are exposed. Black carbon (BC) is one such emission and denotes soot with strong light absorption in the ultraviolet to infrared spectrum. Combustion can also generate brown carbon (BrC) particles, with absorpti
Economic Evaluation of Elective Cesarean Section on Maternal Request Compared With Planned Vaginal Birth—Application to Swedish Setting Using National Registry Data
Objectives: There is a lack of consensus around the definition of delivery by cesarean section (CS) on maternal request, and clinical practice varies across and within countries. Previous economic evaluations have focused on specific populations and selected complications. Our aim was to evaluate the cost-effectiveness of CS on maternal request compared with planned vaginal birth in a Swedish cont
Pulmonary embolism and deep venous thrombosis after COVID-19 : long-term risk in a population-based cohort study
Background: Venous thromboembolism (VTE) (pulmonary embolism [PE] or deep venous thrombosis [DVT]) is common during acute COVID-19. Long-term excess risk has not yet been established. Objectives: To study long-term VTE risk after COVID-19. Methods: Swedish citizens aged 18 to 84 years hospitalized and/or testing positive for COVID-19 between January 1, 2020, and September 11, 2021 (exposed), strat
Dimensionerande snösmältningsintensiteter
Reweighting a Swedish health questionnaire survey using extensive population register and self-reported data for assessing and improving the validity of longitudinal associations
Background In cohorts with voluntary participation, participants may not be representative of the underlying population, leading to distorted estimates. If the relevant sources of selective participation are observed, it is however possible to restore the representativeness by reweighting the sample to resemble the target population. So far, few studies in epidemiology have applied reweighting bas
A directed acyclic graph for interactions
BACKGROUND: Directed acyclic graphs (DAGs) are of great help when researchers try to understand the nature of causal relationships and the consequences of conditioning on different variables. One fundamental feature of causal relations that has not been incorporated into the standard DAG framework is interaction, i.e. when the effect of one variable (on a chosen scale) depends on the value that an
Cookstoves, Candles, and Phthalates – Real Time Physicochemical Characterization and Human Exposure to Indoor Aerosols
Exposure to air pollution is associated with adverse health effects in humans, with special concern for exposure to fine particulate matter (PM2.5). The physicochemical properties of aerosols impact the health effects. Considering that we spend approximately 90% of our time indoors, it is important to gain increased understanding of indoor aerosol concentrations and properties. The overall aim of
English dictionaries, gold and silver standard corpora for biomedical natural language processing related to SARS-CoV-2 and COVID-19
Here we present a toolbox for natural language processing tasks related to SARS-CoV-2. It comprises English dictionaries of synonyms for SARS-CoV-2 and COVID-19, a silver standard corpus generated with the dictionaries and a gold standard corpus of 10 Pubmed abstracts manually annotated for disease, virus, symptom and protein/gene terms. This toolbox is freely available on github and can be used f
