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The biochemical mechanisms underlying glucose-stimulated insulin secretion from pancreatic beta-cells are not completely understood. To identify metabolic disturbances in beta-cells that impair glucose-stimulated insulin secretion, we compared two INS-1-derived clonal beta-cell lines, which are glucose-responsive (832/13) or glucose-unresponsive (832/2). We found that despite a marked impairment o
Assembly of the functional complexes of the mitochondrial respiratory chain requires sophisticated and efficient regulatory mechanisms. In plants, the subunit composition and assembly factors involved in the biogenesis of cytochrome c oxidase (complex IV) are substantially less defined than in mammals and yeast. In this study, we cloned maize (Zea mays) Small kernel 11 (Smk11) via map-based clonin
Glucose transporters (GLUTs) are responsible for transporting hexose molecules across cellular membranes. In adipocytes, insulin stimulates glucose uptake by redistributing GLUT4 to the plasma membrane. In unstimulated adipose-like mouse cell lines, GLUT4 is known to be retained intracellularly by binding to TUG protein, while upon insulin stimulation, GLUT4 dissociates from TUG. Here, we report t
The transformational mode of sustainability science is concerned with generating actionable knowledge and practical solutions to complex sustainability challenges in order to facilitate a transition towards sustainability by strategizing transformational pathways. However, some scholars in the field believe that sustainability science lacks such capacity, since so far greater focus has been put on
This paper estimates labor supply effects for informal caregivers in Sweden using four waves of the SHARE data panel. To give daily or weekly care to a parent, step parent or parent in law is found to be more common among women than among men and is associated with lower employment probability for daily caregivers although the causal direction of the relationship is unclear. No negative effect of
Purpose: The accuracy of analytical dose calculations (ADC) and dose uncertainties resulting from anatomical changes are both limiting factors in proton therapy. For the latter, rapid plan adaption is necessary; for the former, Monte Carlo (MC) approaches are increasingly recommended. These, however, are inherently slower than analytical approaches, potentially limiting the ability to rapidly adap
Failing to communicate current knowledge limitations, that is, epistemic uncertainty, in environmental risk assessment (ERA) may have severe consequences for decision making. Bayesian networks (BNs) have gained popularity in ERA, primarily because they can combine variables from different models and integrate data and expert judgment. This paper highlights potential gaps in the treatment of uncert
Today, we live in an age that is continually witnessing tension, strife and terrorism as a direct product of unequal distribution of wealth and opportunities for a good life. In Uganda for over two and half decades, war, insurgency and deprivation have been the realities of the people living in Northern Uganda. This evidently has lead to an imbalance in the Ugandan society with the North standing
Background: There are known associations between cardiovascular disease (CVD)-related plasma proteins and spirometry measures. Diffusing capacity for carbon monoxide (DLCO) measures gas exchange that can be impaired both by lung and heart diseases. We aimed to study the associations between DLCO and CVD-linked plasma proteins in a population-based cohort without airflow obstruction. Methods: 89 CV
OBJECTIVE: Emergency department length of stay (EDLOS) is linked to crowding and patient outcomes whereas worse prognosis in low socioeconomic status remains poorly understood. We studied whether income was associated with ED process times among patients with chest pain.METHODS: This was a registry-based cohort study on 124,980 patients arriving at 14 Swedish EDs between 2015 and 2019 with chest p
A Palaeolithic diet is an efficacious dietary approach for glycaemic control in type 2 diabetes. Causal mechanisms are body weight loss and glucometabolic effects from differences in included food groups, macronutrient composition, fibre content, and glycaemic load. The aim was to test the hypothesis that characteristic food group differences between a Palaeolithic and a diabetes diet would cause
The impact of obstructive sleep apnea (OSA) and positive airway pressure (PAP) treatment on COVID-19 severity is unclear. In this population-based, nationwide study using multi-register data, we aimed to assess if OSA is a risk factor for COVID-19 severity and how adherence to PAP treatment and clinical characteristics affect the risk. Swedish residents with COVID-19 infection January 2020–May 202
LTH ny tt LUNDS TEKNISKA HÖGSKOLAS NYHETSMAGASIN | NR 2 | 2012 TURN AROUND FOR ENGLISH Mobilspindeln s. 11 Introduktion för populäraste utbildningen Yrke: Industridesigner Forskarna om mobilkrisen LTH-NYTT | NR 2 | 2012 Får vi ett Mobile Village? NÄR SONY MOBILE annonserade sin nerdragning i Lund kändes det som om ”detta har vi varit med om förr”. Det var inte länge sedan Astra Zeneca (AZ) tog sin
https://www.lth.se/fileadmin/lth/omlth/kommunikation/lthnytt/2012nr2_6.pdf - 2026-07-17
D'où Venons Nous? Que Sommes Nous? Où Allons Nous? Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan i
https://www.lth.se/article/dou-venons-nous-que-sommes-nous-ou-allons-nous-1/ - 2026-07-17
The writing of a business plan has become increasingly more highlighted in the academic world during the last few years as courses are being taught on the subject and a number of competitions have been started. Lund Institute of Technology co-organises an annual business plan competition called Venture Cup in order to encourage students and other participants to get into entrepreneurship. People a
