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Diagnostic, prognostic and management aspects of different types of multiple sclerosis

Background: The aim in the thesis is to study diagnostic issues, clinical features, therapy, and prognosis in selected demyelinative disorders of the nervous system: optic neuritis (ON), primary progressive MS (PPMS), and tumefactive MS (a very rare acute demyelinating disorder). Methods: From an initial cohort of 110 patients with ON collected 19 to 31 years ago, a new follow-up survey was cond

The Role of Zinc in Leishmaniasis and Tuberculosis

Popular Abstract in English Bolivia, as with other Latin American countries, is considered to be in an epidemiological transition due to the continued persistence of infectious diseases, and nutritional deficiencies related to poverty and food insecurity, together with an increase in chronic non-communicable diseases mainly related to lifestyle factors. The work presented in this thesis was focuseThe synergistic relation between nutritional deficiency and infection may have negative effects on the immune system, making individuals more vulnerable to infection. Zinc can affect the resistance to infections by modulating cytokine release, and by acting as a cofactor of thymulin, which induces the differentiation of immature T lymphocytes. To investigate the modulation of the immune response b

The Gaia-ESO Survey : Galactic evolution of lithium from iDR6

Context. After more than 50 years, astronomical research still struggles to reconstruct the history of lithium enrichment in the Galaxy and to establish the relative importance of the various 7Li sources in enriching the interstellar medium (ISM) with this fragile element. Aims. To better trace the evolution of lithium in the Milky Way discs, we exploit the unique characteristics of a sample of op

Lovers of the Rose : Islamic Affect and the Politics of Commemoration in Turkish Museal Display

This chapter explores Turkish museal display as an arena for memory-cultural Islamisation, extending beyond the walls of museums. It probes museums as spaces for exhibiting nationalism, and the burgeoning interest in religion and affect within a new museology. It discusses how Turkish expositions have appropriated aspects of such a new museology in restorative-commemorative expositions of the Otto

Enteric Helicobacter and H. pylori in chronic inflammation and cancer of the hepatobiliary tract and pancreas

The Helicobacter genus now consists of at least 26 species, with additional novel species in the process of being validated. Beyond the impact of H. pylori and human health, considerable research has focused on other Helicobacter species isolated from humans and animals and the associated natural diseases that range from subclinical inflammation to cancer in the gastrointestinal and hepatobiliary

Early intervention in management of very preterm growth-restricted fetuses : 2-year outcome of infants delivered on fetal indication before 30 gestational weeks

OBJECTIVES: To describe the outcome of growth-restricted fetuses with absent or reversed end-diastolic flow (ARED) in the umbilical artery delivered on fetal indication before 30 gestational weeks.METHODS: Between 1998 and 2004, 42 fetuses with intrauterine growth restriction (IUGR) and ARED in the umbilical artery were delivered liveborn by Cesarean section on fetal indication before 30 gestation

Access to Cross-Border Healthcare for Older Persons in the European Union : The Interplay between EU Law and Swedish Law

This thesis deals with older persons on the move and their access to cross-border healthcare in the European Union. The number of persons crossing borders within the EU has increased exponentially in recent decades. Free movement has been at the core of the European integration project from its early days. Although it was originally intended to apply only to those who were economically active, theThis thesis deals with older persons on the move and their access to cross-border healthcare in the European Union. The number of persons crossing borders within the EU has increased exponentially in recent decades. Free movement has been at the core of the European integration project from its early days. Although it was originally intended to apply only to those who were economically active, the

Plant major intrinsic proteins - functional implications of expression and localisation studies

Popular Abstract in Swedish Vattentransporten i växter är viktig för en mängd olika processer. De flesta fritidsodlare vet att vattentillgången påverkar växternas utveckling i stor utsträckning. För att solros ska kunna gro, växa, vända sig mot solen och bilda nya frön, behöver vatten flöda på ett kontrollerat sätt genom olika celltyper i växten. Växter transporterar vatten på olika sätt. Över lånPlant water channels are members of the very old Major Intrinsic Protein (MIP) family, with representatives in bacteria, fungi, animals, and plants. The genome of the model plant Arabidopsis thaliana contains 35 MIP genes. Based on protein sequence comparisons, the MIP family has been divided in four subfamilies: the PIP (Plasma membrane Intrinsic Protein), the TIP (Tonoplast Intrinsic Protein), t

Long-term exposure to residential transportation noise and mortality : A nationwide cohort study

Studies have indicated that transportation noise is associated with higher cardiovascular mortality, whereas evidence of noise as a risk factor for respiratory and cancer mortality is scarce and inconclusive. Also, knowledge on effects of low-level noise on mortality is very limited. We aimed to investigate associations between road and railway noise and natural-cause and cause-specific mortality

Ancient Equality Against Modern Democracy : Resources of Critique in Hannah Arendt and Ellen Meiksins Wood

Increasing discontent with the current status of democracy has prompted a renewed interest in Athenian democracy. This article contributes with the first comparative analysis of two political theoreticians – Hannah Arendt and Ellen Meiksins Wood – whose reactivations of ancient political experiences significantly predate recent trends. Despite the fact that Arendt levelled fierce critique against

Economic Impact of Severe Early-Onset Foetal Growth Restriction : A Multicentre Prospective Cohort Study

Objective: Foetal growth restriction (FGR) affects 10% of pregnancies, contributing to 30% of stillbirths. Current management of early-onset FGR (< 32 + 0 weeks' gestation) delivers the foetus before stillbirth or irreversible organ damage. The resulting preterm births create additional risks independent of FGR. We determined the economic cost associated with severe early-onset FGR. Design: Econom

Integrating Tumor-Intrinsic and Immunologic Factors to Identify Immunogenic Breast Cancers from a Low-Risk Cohort : Results from the Randomized SweBCG91RT Trial

PURPOSE: The local immune infiltrate's influence on tumor progression may be closely linked to tumor-intrinsic factors. The study aimed to investigate whether integrating immunologic and tumor-intrinsic factors can identify patients from a low-risk cohort who may be candidates for radiotherapy (RT) de-escalation.EXPERIMENTAL DESIGN: The SweBCG91RT trial included 1,178 patients with stage I to IIA

Hidden Choral Stimuli : The Role of Accent in Aristophanes’ Refrains

The final day of the conference opened with Albin Thörn Cleland’s presentation, “Hidden Choral Stimuli: The Role of Accent in Aristophanes’ Refrains”. His paper examined the interplay of pitch accent, metre and musical melody across metrically identical refrains in pre-Hellenistic Ancient Greek lyric poetry, an aspect that has long remained relatively obscure and misunderstood. Building on Conser

Perioperative systemic chemotherapy in peritoneal carcinomatosis of lymph node positive colorectal cancer treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

BACKGROUND: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) is the preferred treatment of peritoneal carcinomatosis (PC) of colorectal carcinoma. Patients with positive lymph node status have worse survival after CRS-HIPEC, which is probably due to higher rates of systemic failure. In this study, we analysed the effect of administration and timing of systemic chemot

ErbB2 status and the benefit from two or five years of adjuvant tamoxifen in postmenopausal early stage breast cancer

AIM: We aimed to study the importance of erbB2 status in early stage postmenopausal breast cancer for patients who participated in a trial of five vs. two years of adjuvant tamoxifen.PATIENTS AND METHODS: We analysed the erbB2 status of the tumours from 577 patients participating in the trial, either by a DNA amplification assay (n = 181) or by measurement of the protein level with flow cytometry

Entinostat Enhances the Efficacy of Chemotherapy in Small Cell Lung Cancer Through S-phase Arrest and Decreased Base Excision Repair

PURPOSE: Acquired chemoresistance is a frequent event in small cell lung cancer (SCLC), one of the deadliest human malignancies. Histone deacetylase inhibitors (HDACi) have been shown to synergize with different chemotherapeutic agents including cisplatin. Accordingly, we aimed to investigate the dual targeting of HDAC inhibition and chemotherapy in SCLC.EXPERIMENTAL DESIGN: The efficacy of HDACi

Common project brief 2021-06-28 final

Common project brief 2021-06-28 final RESEARCH & POLICY BREIF LOCALISING SUSTAINABLE DEVELOPMENT GOALS AND HUMAN RIGHTS Building Collaborative Initiatives and Synergies between Local Authorities (LAs) and Civil Society Organisations (CSOs) in Sweden, Norway, Åland Islands and North-West Russia June 2021 
 ISBN 978-91-86910-46-4 Research & Policy Brief Localising Sustainable Development Goals and H

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Anti-discrimination in Employment

Anti-discrimination in Employment Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Methods Focus Areas Business and Human Rights International H

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