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Impact of site-specific conjugation strategies on the pharmacokinetics of antibody conjugated radiotherapeutics
Antibody radionuclide conjugates are an emerging modality for targeted imaging and potent therapy of disseminated disease. Coupling of radionuclides to monoclonal antibodies (mAbs) is typically achieved by applying non-site-specific labelling techniques. With the ambition of reducing variability, increasing labelling efficacy and stability, several site-specific conjugation strategies have been de
Meet our researchers: Huntington’s disease – a fascinating mystery
Those who carry the mutated gene will develop the fatal Huntington’s disease at some stage in life. The brain disease, which can be inherited across generations, begins slowly and makes it increasingly difficult for sufferes to regulate their feelings, thoughts, and eventually movements. There is still no treatment. However, Huntington researcher and psychiatrist Åsa Petersén is working hard at it