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The early B cell factor (EBF) is a transcription factor shown crucial for the development of B lymphocytes. The protein is expressed from the earliest stages of B cell development until the mature B cell stage, but the control elements responsible for the regulation of the gene are unknown. In this study, we report of the identification of a promoter region flanking the EBF gene. Several transcrip
Föreliggande rapport behandlar den strategiska forskningsmiljön The Middle East in the Contemporary World (MECW), vid Lunds universitet. Rapporten utgör delrapport II inom ramen för ett projektarbete som deltagarna i programmet Morgondagens forskningsledare genomför 2011–20122. Syftet med projektet är att få en fördjupad förståelse för hur komplexa och strategiskt viktiga forskningsmiljöer kan str
Background-beta-Adrenergic stimulation is the main trigger for cardiac events in type 1 long-QT syndrome (LQT1). We evaluated a possible association between ion channel response to beta-adrenergic stimulation and clinical response to beta-blocker therapy according to mutation location. Methods and Results-The study sample comprised 860 patients with genetically confirmed mutations in the KCNQ1 cha
This paper reports on a search for narrow resonances in diboson production in the [Formula: see text] final state using [Formula: see text] collision data corresponding to an integrated luminosity of [Formula: see text] fb[Formula: see text] collected at [Formula: see text] TeV with the ATLAS detector at the Large Hadron Collider. No significant excess of data events over the Standard Model expect
En grundläggande utgångspunkt i både den kontradiktoriska rättegången inför allmän domstol och i skiljeförfarande är att parterna svarar för bevisningen. Eftersom tillgången till relevant bevisning ofta är avgörande för utgången i en tvist, är möjligheten att göra gällande en motparts eller tredje mans processuella editionsplikt av central betydelse för en informationsfattig part. Vid framställaIn both adversarial litigation and arbitration, a key principle is that each party is responsible for presenting their own evidence. Since the availability of relevant evidence is often crucial to the outcome of a dispute, the ability to invoke the duty of disclosure from an opposing or third party is of particular importance for a party with limited access to information. Section 26 of the Swed
A search for diphoton resonances in the mass range between 10 and 70 GeV with the ATLAS experiment at the Large Hadron Collider (LHC) is presented. The analysis is based on pp collision data corresponding to an integrated luminosity of 138 fb −1 at a centre-of-mass energy of 13 TeV recorded from 2015 to 2018. Previous searches for diphoton resonances at the LHC have explored masses down to 65 GeV,
A search is reported for excited τ-leptons and leptoquarks in events with two hadronically decaying τ-leptons and two or more jets. The search uses proton-proton (pp) collision data at s = 13 TeV recorded by the ATLAS experiment during the Run 2 of the Large Hadron Collider in 2015–2018. The total integrated luminosity is 139 fb −1. The excited τ-lepton is assumed to be produced and to decay via a
Cross-section measurements for a Z boson produced in association with high-transverse-momentum jets (p T ≥ 100 GeV) and decaying into a charged-lepton pair (e + e − , μ + μ −) are presented. The measurements are performed using proton–proton collisions at s = 13 TeV corresponding to an integrated luminosity of 139 fb −1 collected by the ATLAS experiment at the LHC. Measurements of angular correl
Meeting international climate goals require a major reallocation of global investment portfolios. However, in 2016, 74%. of all assets under management were still socially and environmentally unchecked. Research has started to address how finance can support the low-carbon transition, but little is known about how the financial sector itself perceives this transition. This thesis seeks to 1) ident
Humanity is faced with multiple interconnected crises, ranging from the climate breakdown to searing inequalities. There is thus an urgent need to move towards a different socio-political-economic system. Degrowth scholars envision a post-capitalist society centered around ecological and social wellbeing. One way to get there is by building on existing interstitial initiatives. At the same time su
Reindeer husbandry has long been a central element of the traditional livelihood and culture of indigenous Sami people in northern Sweden. However, it faces several challenges from competing land uses, primarily forestry. Different forest conditions are desired by forestry and reindeer husbandry to accommodate each sectors’ distinct interests, promoting high timber and pulp production or improved
The global pandemic of Covid-19 has drastically changed the behaviour of citizens around the world. This research aims to identify actions that ensure low-carbon, inclusive forms of mobility that respond to the behavioural changes during Covid-19. The city of Hamburg, Germany, and its problems with transport-related emissions and socio-economic inequalities serve as a representative case study. Th
In December 2019, news came from China about a mysterious virus that infected people in the Chinese city of Wuhan. During the following weeks the disease spread further to a number of countries all over the world (DW 2019). The new disease turns out to be very dangerous and highly contagious. While the pandemic spread and people died disinformation started to spread in the media, social media, and
The Swedish rules for closely held companies were enacted to combat income conversion abuse in limited liability companies where natural persons acted as both owners and employees. In the Swedish Income Tax Act, employment income is taxed according to a progressive rate while capital income is taxed according to a flat rate. The wage remuneration rule may increase the amount of dividend that the a
I denna uppsats härleds och testas en ny omviktningsalgoritm med vars hjälp det nativa tillståndet av aminosyresekvenser, bestående av 16 aminosyror, kan förutspås. Algoritmen används till att kartlägga de neutrala näten av α-helixes och β-sheets inom ett kontinuerligt proteinmodell. För att undersöka omviktningsalgoritmens potential för att förutsäga den termodynamiska stabiliteten av olika aminIn this thesis, a new reweighting algorithm for predicting the native conformations of amino acid sequences, consisting of 16 residues in a reduced representation continuous protein model, is derived and tested to map neutral nets of α-helices and β-sheets. For examining the potential of the reweighting algorithm for predicting the thermodynamic stability of amino acid sequences, it is applied to
This thesis is concerned with history within Nick Clegg’s and Nigel Farage’s political discourse during the six months leading up to the 2016 referendum on the United Kingdom’s membership in the European Union. Using Thematic Analysis combined with Klas-Göran Karlsson’s typology of the use of history, Jörn Rüsen’s typology of historical narrative and drawing on the theoretical framework of histori
Chronic wounds are an emerging healthcare issue and current methods of healing chronic wounds address bacteria but are ineffective against resistant bacteria and the biofilm formation commonly observed in these wounds. Antimicrobial peptides (AMPs) derived from the endogenous wound healing system have been shown to combat bacterial infections, exhibit immunomodulatory effects, as well as improvi
The thesis explores the interaction between patent rights for Standard Essential Patents(SEP) and competition law, particularly Article 102 of the Treaty on the Functioning of the European Union(TFEU), within the context of the European Union(EU) , and compares this interaction with the relevant provisions in the proposed EU SEP regulation COM(2023)232. Three research questions will be discussed:
The steel industry is one of the most polluting industries globally. There exists an EU waste shipment proposal that aims to restrict the EU export of waste in order to raise safe, environmental standards and circularity within the EU. Under this proposal, steel scrap is defined as waste and since the EU is the largest exporter of steel scrap globally, this has implications for the EU steel indust
