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Ligands for the benzodiazepine-binding site of the GABAA receptor can belong to structurally diverse classes of compounds including, in spite of the name of the binding site, many non-benzodiazepine structures. The GABAA receptor is a ligand-gated ion channel assembled of five subunits from eight different classes with multiple isoforms. The physiological effect elicited by benzodiazepines is beli

We find the Shannon limit to bit error rate (BER) as a function of E_b/N_0 for linear coded modulations. Error performance of TCM and other schemes can be compared to this curve. As the bandwidth of the signals in Hz-s/data bit drops, capacity becomes sensitive to the stopband spectrum, and the limit moves strongly away from the BER of practical systems when the stopband rolloff is not severe.

In this paper, wave splitting technique is applied to a homogeneous Timoshenko beam. The purpose is to obtain a diagonal equation in terms of the split fields. These fields are calculated in the time domain from an appropriate set of boundary conditions. The fields along the beam are represented as a time convolution of Green functions with the excitation. The Green functions do not depend on the

A relation between the radiation resistance and the quasi-static polarizability, input capacitance, and input inductance for small electric dipole antennas is investigated. The relation follows from the forward scattering sum rule and sum rules for the input impedance together with resonance models for the partial realized gain and the reflection coefficient.

In this master thesis we consider some phenomenological aspects of two-Higgs-doublet models, both elementary and composite ones. The emphasis is on calculating and understanding first order phase transitions in such models, constrained to be in agreement with existing collider data on the Higgs sector. We also consider the contribution to the gravitational wave background of the universe that woul

Objective To develop evidence-based recommendations for the diagnosis of knee osteoarthritis (OA). Methods The multidisciplinary guideline development group, representing 12 European countries, generated 10 key propositions regarding diagnosis using a Delphi consensus approach. For each recommendation, research evidence was searched systematically. Whenever possible, the sensitivity, specificity a

The Tile hadronic calorimeter of the ATLAS detector has undergone extensive testing in the experimental hall since its installation in late 2005. The readout, control and calibration systems have been fully operational since 2007 and the detector has successfully collected data from the LHC single beams in 2008 and first collisions in 2009. This paper gives an overview of the Tile Calorimeter perf

The MAX IV pro-injector will have one thermionic and one photocathode S-band RF gun, where the former will be used for ring injections. During ring injections, the bunches leaving the pre-injector have a structure that consists of ten 10 ns bunch trains, each containing three bunches. A chopper system consisting of two striplines and an adjustable aperture is used, where the desired bunch structur

Despite the advancement in background rejection techniques, observation of the very-high-energy gamma-ray sky by imaging atmospheric Cherenkov telescopes (IACTs) are subject to an irreducible background from gamma-like hadron- or electron-induced air showers. The determination of this residual background is crucial for accurate spectral and spatial measurements. The Cherenkov Telescope Array (CTA)

The management and conservation of lakes should be conducted in the context of catchments because lakes collect water and materials from their upstream catchments. Thus, the datasets of catchment-level characteristics are essential for limnology studies. Lakes are widely spread on the Tibetan Plateau (TP), with a total lake area exceeding 50000km2, accounting for more than half of the total lake a