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It has become necessary to estimate the quantities of runoff by knowing the amount of rainfall to calculate the required quantities of water storage in reservoirs and to determine the likelihood of flooding. The present study deals with the development of a hydrological model named Hydrologic Engineering Center (HEC-HMS), which uses Digital Elevation Models (DEM). This hydrological model was used

Following the successful operation of the Multipole Injection Kicker (MIK) in the MAX IV 3 GeV storage ring, we plan to introduce a similar device in the MAX IV 1.5 GeV ring. In order to assess the effectiveness of such device and to define its working parameters, we performed a series of studies aimed at understanding the beam dynamics related to the injection process. In this paper we describe t

Recent years’ publications have shown how valuable information can be in the integrity management of civil structures. Monitoring systems increase the knowledge about the structural state, improving the prioritization of the interventions, and the selection of optimal maintenance strategy and thereby allowing for budget optimization and risk minimization. This paper investigates the effect of mult

The thesis explores the ‘missing link’ in the study of priority-setting for research, development, and innovation (RDI), namely the processes of implementing RDI priorities, and the consequences of these processes. It does so by focusing on how choices, actions, and motivations of implementers of RDI priorities established elsewhere in the policy system enact, or carry out, the priorities, resulti

Population ageing is a fact of all advanced economies. Fewer people are born all the while current members live longer. The support which old people have come to depend on, for example through elderly care and pensions, thus becomes increasingly expensive. This accentuates an assurance problem. Although it has been and still is the case that the young are willing to support the currently old, this

The ATLAS physics program at the High Luminosity LHC (HL-LHC) calls for a precision in the luminosity measurement of ±1%. A larger uncertainty would represent the dominant systematic error in some precision measurements, including the Higgs sector. To fulfil such requirement in an environment characterized by up to 140 simultaneous interactions per bunch crossing (200 in the ultimate scenario), AT

For many decades the CERN North Area facility at the Super Proton Synchrotron (SPS) has delivered secondary beams to various fixed target experiments and test beams. In 2018, two new tertiary extensions of the existing beam lines, designated "H2-VLE" and "H4-VLE", have been constructed and successfully commissioned. These beam lines have been designed to provide charged particles of both polaritie

The device or the formulation? Which one governs drug dispersibility from the inhaler? To address this question, three budesonide-containing reservoir DPIs: Novopulmon Novolizer®, Giona Easyhaler® and DuoResp Spiromax®, were analyzed using the Next Generation Impactor, NGI. Thereafter, the devices were carefully opened, emptied, and formulations were switched between devices. Finally, three ‘proto

OBJECTIVE: To investigate gastrointestinal infection episodes (GIEs) in relation to the appearance of islet autoantibodies in The Environmental Determinants of Diabetes in the Young (TEDDY) cohort.RESEARCH DESIGN AND METHODS: GIEs on risk of autoantibodies against either insulin (IAA) or GAD (GADA) as the first-appearing autoantibody were assessed in a 10-year follow-up of 7,867 children. Stool vi

After many years of preclinical development, cell and gene therapies have advanced from research tools in the lab to clinical-grade products for patients, and today they constitute more than a quarter of all new Phase I clinical trials for Parkinson's disease. Whereas efficacy has been convincingly proven for many of these products in preclinical models, the field is now entering a new phase where

The ATLAS experiment has developed extensive software and distributed computing systems for Run 3 of the LHC. These systems are described in detail, including software infrastructure and workflows, distributed data and workload management, database infrastructure, and validation. The use of these systems to prepare the data for physics analysis and assess its quality are described, along with the

This paper presents the characterisation and testing of the first wafer-scale monolithic stitched sensor (MOSS) prototype developed for the ALICE ITS3 upgrade that is to be installed during the LHC Long Shutdown 3 (2026–2030). The MOSS chip design is driven by the truly cylindrical detector geometry that imposes that each layer is built out of two wafer-sized, bent silicon chips. The stitching tec

Digital technologies in welfare organizations frequently generate gaps, ambiguities, andmisalignments that require professional intervention. Yet prior research has tended to portrayfrontline workers mainly as resistant or adaptive actors, leaving under-examined their activecontributions to sustaining broader digital infrastructures. This article introduces the concept ofdigital compensatory work

A search for the dimuon decay of the Higgs boson is presented based on pp collision data recorded by ATLAS during Run 3 of the Large Hadron Collider, corresponding to an integrated luminosity of 165 fb-1 at √s = 13.6 TeV. To enhance the sensitivity, the results are combined with those from Run 2. An excess of events over the background is observed with a significance of 3.4σ (2.5σ expected). The b