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Galiellalactone Synthetic Studies

In search for remedies and treatments, science has recurred to Mother Nature. This is where galiellalactone was found, a fungal metabolite isolated from Galiella rufa in 1990. Since then chemists and biologists have been studying its properties and found it to be a potential candidate against castration-resistance prostate cancer (CRPC). The development of a new drug requires many studies of the c

An In-Cycle based NOx Reduction Strategy using Direct Injection of AdBlue

In the last couple of decades, countries have enacted new laws concerning environmental pollution caused by heavy-duty commercial and passenger vehicles. This is done mainly in an effort to reduce smog and health impacts caused by the different pollutions. One of the legislated pollutions, among a wide range of regulated pollutions, is nitrogen oxides (commonly abbreviated as NOx). The SCR (Select

What control engineers should know about industry 4.0

Control engineering is a well-established discipline with a long and prominent his-tory1. It is diverse in its applications but has a strong unifying core to it: the notion ofdynamic systems and control theory. Many engineers will have encountered it as partof their education, as control engineering courses are taught to electrical, mechanical,chemical, aerospace, and industrial engineers. Quite o

Technological systems and development blocks

Successful technological transitions require the alignment of technologies, capabilities, infrastructure, and institutions across a wide array of industries and involving many agents. In such processes, synergies and complementarities across different fields of economic activity are crucial. When such complementarities are missing, imbalances emerge, which, in the absence of innovation, may stifle

Laminar burning velocity of hydrogen and flame structure of related fuels for detailed kinetic model validation

The laminar burning velocity and the flame structure are common targets for combustion studies aimed at detailed kinetic model development. In the present work, fuels relevant to hydrogen combustion were considered. The laminar burning velocity of rich and lean hydrogen flames was studied experimentally and numerically, including its pressure dependence in rich mixtures and temperature dependence

Central bank power is a matter of faith

This paper reconsiders how central banks get involved in the process of determining nominal variables such as market interest rates and inflation rates. It is argued that the traditional story deriving central bank power from its monopoly of issuing base money is flawed. That story - in its various guises - is based on the quantity equation. This equation, however, is only applicable in the hypoth

Multilevel Monte Carlo Methods for Simulated Maximum Likelihood Inference in Multivariate Diffusions

Multilevel Monte Carlo is a novel method for reducing the computational cost when computing conditional expectations of stochastic processes. This paper considers the transition density for diffusion processes. It is known that the transition density can be written as an expectation by utilizing the law of total probability combined with the Markov property. This idea is combined with the multilev

Dynamic Optimization of Transportation Networks with Delays

The topic of this thesis is the optimal control of transportation networks. The problem studied is a dynamical extension of a classical problem in economics, in which the objective is to distribute goods to maximize welfare, whilst satisfying constraints on production and consumption. The main contribution is to show that for a class of welfare functions and dynamics, the optimal control is highly

Data Diplomacy as Governance Practice : The 32nd European Conference on Information Systems

The implementation of new data regulation has put pressure on organizations to govern their data. However, research on data governance typically focuses on the optimal design of rules and decisionmaking about data. In this paper, we argue that the significant work that goes into responding, when data use is challenged on the basis of regulation, is a legitimate subset of data governance practice.