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Popular Abstract in Swedish De flesta primärar hjärntumörer utgår ifrån astrocyter, oligodendrocyter och ependymala celler, som är hjärnvävnadens egna celler. Cirka hälften av dessa tumörer ingår i en grupp där tumörtypen heter gliom. Glioblastoma multiforme (GBM) är den mest elakartade tumören inom denna grupp och också den vanligast förekommande.Trots stora forskningssatsningar är behandlingsstrGlioblastoma multiforme (GBM) is the most malignant and also the most common form of brain tumour in humans. The overall aim of this thesis was to investigate morphological and diagnostics features in human GBM that may be of importance for prognosis and treatment. Immunohistochemically stained tissue sections have been microscopically analysed regarding immuno-reactive cells, cell proliferation,

Objectives. The aims of the present study were to analyze patient- and management-related predictors for outcome after open (OR) and endovascular repair (EVAR) of ruptured abdominal aortic aneurysm (rAAA). Design. Retrospective study. Materials. The in-hospital registry of Malmo University Hospital identified 162 patients operated on due to rAAA between 2000 and 2004. Methods. Patient- and managem

When analysing new types of sewage systems, knowledge is needed on the composition of the different wastewater fractions. The computer model URWARE, developed from the model ORWARE, is intended to analyse and compare different wastewater system structures, e.g. to compare wastewater systems where urine and/or faeces are source separated with conventional wastewater systems, where the different was

Popular Abstract in Swedish Många olika proteiner kan produceras med hjälp av rekombinanta DNA tekniker. Ofta sätts vektorn som kodar för det rekombinanta proteinet in i bakterien E. coli, då den är välkänd. Det är viktigt att producera mycket celler för att uppnå hög produktivitet. Detta görs genom att näringsämnet (ofta glukos) tillsätts kontinuerligt till en så kallad semisats reaktor. TillsatsThe recombinant DNA techniques have made it possible to produce many different proteins for a wide range of applications. The vector encoding for the recombinant protein is often inserted in the bacterium E. coli as it is a well studied and a well-known organism. To achieve a high productivity, it is important to reach a high cell density. This is obtained through fed-batch operation where the nut

Tetraplegic patients have to depend upon someone else for moving the wheelchair or typing on a computer. One of the ways to make them independent is by using tongue-controlled in-mouth wireless devices. This letter presents antennas and propagation for such devices in 2.45 GHz ISM band. A monopole and a loop antenna suitable in size and performance is presented for such devices. The propagation li

The four-kallikrein panel and the Prostate Health Index (PHI) have been shown to improve prediction of prostate cancer (PCa) compared with prostate-specific antigen (PSA). No comparison of the four-kallikrein panel and PHI has been presented.

A number of minimal problems of structure from motion for cameras with radial distortion have recently been studied and solved in some cases. These problems are known to be numerically very challenging and in several cases there were no practical algorithms yielding solutions in floating point arithmetic. We make some crucial observations concerning the floating point implementation of Gröbner bas

To describe the relatives' experiences of information and support while heart or lung transplant candidates were waiting for a transplantation.

The Matern covariance function is a popular choice for modeling dependence in spatial environmental data. Standard Matern covariance models are, however, often computationally infeasible for large data sets. Recent results for Markov approximations of Gaussian Matern fields based on Hilbert space approximations are extended using wavelet basis functions. Using a simulation-based study, these Marko

Previous studies have shown that fossil energy systems can be a conflict objective, means or cause. This study explores how renewable energy (RE) systems can interact with conflicts and to what extent the risk of different conflicts may change. Renewable resources, in contrast to conventional fossil resources, are more difficult to control in time and space. RE systems depend on exploiting flows r

The synthesis of four molybdenum and tungsten complexes bearing tetradentate tripodal amino bisphenolate ligands with either hydroxyethylene (1a) or hydroxyglycolene (1b) substituents is reported. The molybdenum dioxo complexes [MoO2L] (L = 2a, 2b) and tungsten complexes [WO2L] (3a, 3b) were synthesized using [MoO2(acac)(2)] and [W(eg)(3)] (eg = 1,2-ethanediolato, ethylene glycolate), respectively

It is of highest importance to find proteins responsible for breast cancer dissemination, for use as biomarkers or treatment targets. We established and performed a combined nontargeted LC MS/MS and a targeted LC SRM workflow for discovery and validation of protein biomarkers. Eighty breast tumors, stratified for estrogen receptor status and development of distant recurrence (DR +/-), were collect

This review will discuss methodologies and applicability of key inflammatory models of respiratory disease in proof of concept or proof of efficacy clinical studies. In close relationship with these models, induced sputum and inflammatory cell counts will be addressed for phenotype-directed drug development. Additionally, important regulatory aspects regarding noninvestigational medicinal products

Energy-rich methane can be harnessed from seaweed deposits by anaerobic digestion. However, the high heavy metal content in the seaweed and its digestates limits their use as fertilisers. Heavy metal contaminants from solid seaweed can be removed by, mobilisation into a liquid phase and subsequent metal ions adsorption. In this laboratory-scale study, pretreatment strategies for enhancing seaweed

Background More effective prevention of suicide requires a comprehensive understanding of sociodemographic, psychiatric and somatic risk factors. Previous studies have been limited by incomplete ascertainment of these factors. We conducted the first study of this issue using sociodemographic and out-patient and in-patient health data for a national population. Method We used data from a national c

The rotation of water in noble gas matrices has been studied. It is shown that the rotation-translation coupling model of Friedmann and Kimel predicts rotation line spacings, which are close to the experimental observations for H2O, D2O, and HDO, when gas phase rotation constants are used. The model gives intensity estimates in reasonable agreement with the observations for the local oscillator ba

Sweden has experienced a national value-based pricing (VBP) system for innovative outpatient drugs operated by the Pharmaceutical Benefits Board - LFN (now called the Dental and Pharmaceutical Benefits agency - TLV) since 2002. VBP has the character of a monopoly system, leading to reimbursement decisions where usage of new medicines is limited to subgroups and not the population for which the dru