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BackgroundCognitive-behavioral therapy (CBT) and serotonin reuptake inhibitors (SRIs) are recommended treatments for pediatric obsessive-compulsive disorder (OCD), but their relative efficacy and acceptability have not been comprehensively examined. Further, it remains unclear whether the efficacy of in-person CBT is conserved when delivered in other formats, such as over telephone/webcam or as In
Objectives: Depression is increasing and is a leading cause of disease burden among adolescents. Available evidence-based treatments with medication or psychotherapy have modest effects. Aerobic exercise is a hopeful alternative as an augmenter or a stand-alone treatment. Qualitative studies have shown that participants in group exercise for adolescent depression experienced improved mood and a se
Background: Outcome measurement is essential to progress clinical practice and improve patient care. Aim: To develop a Core Outcome Set for best care for the dying person. Design: We followed the Core Outcome Measures in Effectiveness Trials (COMET) Initiative guidelines, which involved identifying potential outcomes via a systematic literature review (n = 619 papers) and from participants in the
Groundwater drought, as a form of hydrological drought, embodies the distinctive characteristics of the aquifer and human-induced disruptions within the hydrological system. The intricate nature of groundwater flow systems, coupled with challenges in acquiring field observations related to aquifers, poses significant challenges in quantitatively characterizing groundwater drought. The present pape
There is a need for ground-breaking technologies to boost crop yield, both grains and biomass, and their processing into economically competitive materials. Novel cereals with enhanced photosynthesis and assimilation of greenhouse gasses, such as carbon dioxide and ozone, and tailored straw suitable for industrial manufacturing, open a new perspective for the circular economy. Here we describe the
This study investigates temporal relationships between vegetation growth, rainfall, and soil moisture for six sites located in sub-Saharan and southern Africa for the period 2005-2009. Specifically, seasonal components of time series of Normalized Difference Vegetation Index (NDVI) and Enhanced Vegetation Index (EVI) composites from the Moderate Resolution Imaging Spectroradiometer (MODIS) and hal
This paper deals with the contemporary concern of business service-orientation. The paper suggests that service-oriented Business Information Systems Development (BISD) permits quality aspects, -“ilities” e.g.; maintainability and modifiability, of BISs and BISD. In addition, this paper departs from viewing a Business Information System (BIS) as services and suggests Separation of Concerns (SoC) a
Abstract not available
The reliable prediction of optical and fundamental gaps of finite size systems using density functional theory requires to account for the potential self-interaction error, which is notorious for degrading the description of charge transfer transitions. One solution is provided by parametrized long-range corrected functionals such as LC-BLYP, which can be tuned such as to describe certain properti
To validate cardiac output measurements by ultrasound dilution technology (COstatus monitor) against those obtained by a transit-time ultrasound technology with a perivascular flow probe and to investigate ultrasound dilution ability to estimate pulmonary to systemic blood flow ratio in children.
Boronate-containing thin polyacrylamide gels (B-Gel), polymer brushes (B-Brush) and chemisorbed organosilane layers (B-COSL) were prepared on the surface of glass slides and studied as substrates for carbohydrate-mediated cell adhesion. B-COSL- and B-Brush-modified glass samples exhibited multiple submicron structures densely and irregularly distributed on the glass surface, as found by scanning e
The intention of this thesis was to evaluate the effects of inflammation at very preterm birth on subsequent morbidity, as well as on the neuro-protective IGF-system. Prospective clinical studies of very preterm infants constituted a base for the evaluation. Temporal changes in levels of cytokines were chosen as markers of an induced inflammatory response and were evaluated together with component
Great Spotted and Syrian Woodpeckers (Dendrocopos major and D. syriacus) are known to hybridize in nature; however, the extent of this phenomenon is not known due to difficulties in hybrid detection based on plumage analyses. Here, we tested five markers (one mitochondrial and four nuclear) and a set of six microsatellite loci for the identification of these two Woodpeckers and their hybrids. Sequ
The reaction kinetics of Candida antarctica lipase B (CalB) in the commercially available preparation Novozym (R) 435 (N435) were compared to those of preparations of CalB immobilised on Accurel (R) MP1000 (porous polypropylene). Two polypropylene preparations were made using enzyme loadings of 0.2% and 2% (w/w). All three preparations were used in hydrolysis as well as transesterification of two
The deficiency or abnormal function of von Willebrand factor (VWF) causes von Willebrand disease (VWD), the most frequent inherited bleeding disorder. The laboratory diagnosis of VWD can be difficult as the disease is heterogeneous and an array of assays is required to describe the phenotype. Basic classification of quantitative (type 1 and 3) and qualitative (type 2) VWD variants requires determi
The aim of this study was to compare the conventional combination of three-dimensional dosimeter (nPAG gel) and readout method (MRI) with other combinations of three-dimensional dosimeters (nPAG gel/Presage (TM)) and readout methods (optical CT scanners). In the first experiment, the dose readout of a gel irradiated with a four field-box technique was performed with both an Octopus IQ scanner and
The Integrated Deposition Model (IDEM) was improved by incorporating a novel multilayer biochemical dry deposition module for gases. The aerosol and base cation deposition module was adopted from IDEM. For evaluation of primary and ecosystem productivity, carbon respiration schemes were included. The resulting Framework for Atmosphere- Canopy Exchange Modelling (FACEM) was then evaluated by the ca
The development of chronic bronchitis (CB) and chronic obstructive airway disease (COAD) seems to be related to inflammatory changes of airway structure. However, the cause and the exact location and type of these changes resulting in altered airway function are not known. Mucosal inflammation is characterized by the recruitment of granulocytes, macrophages and lymphocytes as well as by the sheddi
