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To investigate the effects of a vitamin D3 analogue (BXL628) in a model of chronic cystitis, as calcitriol analogues might be an interesting new therapeutic option for interstitial cystitis, for although the cause of the disease remains unclear, the increase in mast cells in the mucosa and detrusor muscle are significant. We devised a mouse model of allergen-induced allergic cystitis that is assoc

Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against human cytomegalovirus, making it an attractive antigen for active and passive immunoprophylaxis. The immunodominant region on gB is the antigenic domain 1 (AD-1), a complex structure which requires a minimal linear amino acid sequence of more than 75 amino acids (aa 552-635) for antibody binding. We

Den förrädiska antikroppen Streptokocker är en lömsk bakterie som har många olika sätt att ta sig runt vårt immunförsvar. Den kan låtsas vara en del av vår kropp genom att klä sig själv i en proteinkapsel som är väldigt likt ett mänskligt protein, bryta ned våra celler med hjälp av utsöndrade gifter och använda vårt immunförsvar mot oss genom att binda antikroppar till sig själv. En virulensfaktoThe Group A streptococcus (GAS) (Streptococcus pyogenes) is a significant human pathogen known for causing a diverse range of diseases, spanning from mild diseases such as pharyngitis to life-threatening diseases such as necrotizing fasciitis. Its virulence comes from a plethora of immune evasion mechanisms, but the M protein with its hypervariable region and ability to bind human proteins, stands

Brevmall Postadress Box 117, 221 00 Lund Besöksadress Paradisgatan 5C Telefon 046-222 77 71, 046-222 00 00 E-post anneli.wiklander@fs.lu.se Rektor Föreskrifter rörande hantering av ekonomiska intresse- konflikter relaterade till viss amerikansk forskningsfinansiering Bakgrund I samband med ansökan om forskningsbidrag och för att kunna ta emot forskningsmedel från USA:s statliga finansiärer, särski

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/foreskrifter-rorande-hantering-av-ekonomiska-intressekonflikter-relaterade-till-viss-amerikansk-forskningsfinansiering.pdf - 2026-06-01

AMDS.GlOW36 Language Faculty, Complexity Reduction and Symmetry Breaking Anna Maria Di Sciullo, Université du Québec à Montréal 1. I assume that the Language Faculty is stable, it does not vary though time and space, and that language development requires experience (Chomsky 1995, 2005, 2011). I develop the view that language evolutionary development is the result of the interaction of the languag

https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_glow36/Biolinguistics/Language_Faculty__Complexity_Reduction_and_Symmetry_Breaking.pdf - 2026-05-30

Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei

Freshwaters bring a notable contribution to the global carbon budget by emitting both carbon dioxide (CO2) and methane (CH4) to the atmosphere. Global estimates of freshwater emissions traditionally use a wind-speed-based gas transfer velocity, kCC (introduced by Cole and Caraco, 1998), for calculating diffusive flux with the boundary layer method (BLM). We compared CH4 and CO2 fluxes from BLM wit

MILJÖVETENSKAP Schema 2020-10-26 Kurs: MVEN16 Klimatpolitik, samhällsstyrning och kommunikation, HT20 Kursansvarig: RH: Roger Hildingsson, Statsvetenskapliga inst; roger.hildingsson@svet.lu.se Lärare: CD: Carl Dalhammar, IIIEE; carl.dalhammar@iiiee.lu.se JK: Jamil Khan, Miljö- och energisystemanalys, LTH; jamil.khan@miljlo.lth.se MR: Markku Rummukainen, CEC SU: Sara Ullström, LUCSUS; sara.ullstrom

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/2020-10/Schema%20MVEN16%20HT20_26okt20.pdf - 2026-05-31

Popular Abstract in English Globalization and new technologies in transportation and communication have opened the doors for partnerships beyond the national and regional borders, making business survival more complex than ever before. We can see more companies outsourcing different aspects of their business in order to focus on one or a few core competencies, which would potentially gain them morIn this dissertation, we discuss how buyers practice purchasing strategies in an asymmetric power situation favoring suppliers, and how their purchasing strategies practiced impact their purchasing power and buyer-supplier relationships. Organizations enter exchange relationships to access required resources not produced internally, and are exposed to uncertainty from not being able to fully contr

Homozygous C2 deficiency (C2D) is the most common deficiency of the classical complement pathway in Western countries. It is mostly found in patients with autoimmune disease or susceptibility to bacterial infections and in healthy persons. We wished to assess to what extent other immunological factors might explain differences of susceptibility to infections in C2D. For this reason, 44 Swedish pat

In anti-glomerular basement membrane (anti-GBM) disease, IgG class autoantibodies induce rapidly progressive glomerulonephritis. Regrettably, many patients are diagnosed at a late stage when even intensive conventional treatment fails to restore renal function The endopeptidase IdeS (Immunoglobulin G degrading enzyme of Streptococcus pyogenes) (imliflidase) rapidly cleaves all human IgG subclasses

The reactivity of the benzenedithiolate (bdt)-bridged complex [Fe2(CO)6(µ-bdt)] with arsine, stibine and phosphine ligands has been studied. The new mono- and disubstituted complexes [Fe2(CO)5(EPh3)(µ-bdt)] (E = As, 1; E = Sb 3) and [Fe2(CO)4(EPh3)2(µ-bdt)] (E = As, 2; E = Sb, 4) and the previously reported [Fe2(CO)4(PPh2H)2(µ-bdt)] (5) have been prepared by Me3NO-initiated carbonyl substitution r

We introduce rigorous theory for deriving first and second order backpropagation methods for Deep Neural Networks (DNN) whilst satisfying existing theory in DNN optimization. We begin by formally defining a neural network with its respective components and state the first and second order chain rule with respect to its partial derivatives. The partial derivatives in the chain rule formula are rela

Massive Multiple-Input Multiple-Output (MIMO) communication systems are being investigated intensively for positioning services. Enhancing the accuracy on these services in terms of accurate positioning of users is an important goal to improve related applications in the future. Convolutional Neural Networks (CNNs) has been proposed to infer the position of a user from Channel State Information (C

https://www.mediatryck.lu.se/conference - 2026-05-31

Between 2014 and 2022, Sweden introduced a feminist foreign policy (FFP), which entailed a “systematic gender equality perspective throughout foreign policy”. This chapter focuses on how FFP was practiced and implemented by officials at Swedish Embassies around the world. Using a framework of practice theory, implementation theory and feminist institutionalism, the overarching questions guiding th

https://www.lu.se/evenemang/robotics-week-school-classes-24-26-november - 2026-06-01

Popular Abstract in Swedish Denna avhandling handlar om modeller för plana solfångare, transparent isolering och verkningsgradsfaktorer. En ekvation för energiutbytet från en glasad plan solfångare härleds genom att modellera verkningsgradsfaktorn, F´, som en summa av en konstant och en temperaturberoende del. Ett alternativt sätt att testa en plan solfångare, baserat på denna modell, föreslås. EThis thesis deals with models of flat plate collectors, transparent insulation and efficiency factors. An equation for the energy output from a glazed flat plate collector is derived by modelling the collector efficiency factor, F´ as the sum of a constant and a temperature dependent part. An alternative way of testing a flat plate collector, based on this model, is suggested. A complete set of a