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Development of an Ultrasensitive Capacitive DNA-sensor: A promising tool towards microbial diagnostics

Popular Abstract in English A handful of diseases-causing pathogenic microorganisms claim millions of lives worldwide each year, mainly due to limited diagnostic capabilities. The lack of simple, cost-effective, sensitive and rapid on-site diagnostic tools lead to delays in the diagnoses with a subsequent lag in treatment, which in turn can result in serious complications or even loss of lives. Fast and sensitive detection of pathogenic microbial cells is a highly important task in medical diagnostics, environmental analysis and evaluation of food safety. Accordingly, the idea of microorganism identification by the recognition of specific DNA sequence using electrochemical technique is one of the leading researches in the development of diagnostic devices. In other words, it should only

Impact of site-specific conjugation strategies on the pharmacokinetics of antibody conjugated radiotherapeutics

Antibody radionuclide conjugates are an emerging modality for targeted imaging and potent therapy of disseminated disease. Coupling of radionuclides to monoclonal antibodies (mAbs) is typically achieved by applying non-site-specific labelling techniques. With the ambition of reducing variability, increasing labelling efficacy and stability, several site-specific conjugation strategies have been de

A new Green Sample Preparation And Chromatography Method for Nicotine and Nicotine Related Substances in Nicotine Chewing gum

Heptan, går det att ersätta? Mycket brandfarlig vätska och gas; irriterar hud, giftig för vattenlevande organismer med långtidseffekter, kan vara dödlig vid förtäring samt inandning. Detta är en varningstext från ett säkerhetsblad till HEPTAN, ett vanligt förekommande lösningsmedel vid kemiska analyser i Sverige. Bara i ett provupparbetningsförsök på en produkt och för en analys på ett före-tag i

Föreskrifter rörande hantering av ekonomiska intressekonflikter relaterade till viss amerikansk fors

Brevmall Postadress Box 117, 221 00 Lund Besöksadress Paradisgatan 5C Telefon 046-222 77 71, 046-222 00 00 E-post anneli.wiklander@fs.lu.se Rektor Föreskrifter rörande hantering av ekonomiska intresse- konflikter relaterade till viss amerikansk forskningsfinansiering Bakgrund I samband med ansökan om forskningsbidrag och för att kunna ta emot forskningsmedel från USA:s statliga finansiärer, särski

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/foreskrifter-rorande-hantering-av-ekonomiska-intressekonflikter-relaterade-till-viss-amerikansk-forskningsfinansiering.pdf - 2026-05-06

The effect of carrier particle size on the performance of adhesive mixtures for inhalation

Despite being subject to a multitude of investigations, the effect of carrier particle size on the performance of adhesive mixtures for inhalation is still not well understood. This study, involving three differently sized lactose carriers, all with the regular ‘tomahawk’ particle shape, aims to provide fundamental insight into this topic. Fine particle fraction (FPF) data for binary formulations

Ageing, social participation, and everyday mobility : Facilitating age-friendly environments

Due to the increasing share of older people worldwide, the United Nations has directed an initiative towards a "decade of healthy ageing" to promote "age-friendly environments". This study aims to gain a deeper understanding of how to promote social participation and everyday mobility in later life. The ambition is to increase the knowledge about how to create more age-friendly environments and so

Determination of carbonate-C in biochars

Although carbonate-carbon (C), an integral part of biochar-C, contributes to the liming properties of that material, it also interferes with the estimation of the stable organic C fraction in biochars. In this study, four methods were compared in order to quantify the carbonate-C in biochars: two direct (a titrimetric procedure and thermogravimetric analysis, TGA), and two indirect (acid treatment

A highly sensitive bead-based flow cytometric competitive binding assay to detect SARS-CoV-2 neutralizing antibody activity

Accurate detection of SARS-CoV-2 neutralizing antibody (nAb) is critical for assessing the immunity levels after virus infection or vaccination. As fast, cost-effective alternatives to viral infection-based assays, competitive binding (CB) assays were developed to quantitate nAb by monitoring the ability of sera to inhibit the binding of viral spike (S) protein to the angiotensin converting enzyme