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Significant advancements in audio transport, encoding, and processing power in embedded systems constitute the foundation of today’s speakers. Transitioning the digitalized audio data transmission to Audio over IP (AoIP) has opened the potential to transmit audio with the same network flexibility as other services using packet-based networks, such as voice over IP or video over IP. This thesis pri
This master thesis aims to investigate the positioning accuracy improvements of device localization by the implementation of AI/ML functionalities. In this project, we use the fifth-generation(5G) New Radio (NR) system and focus on indoor factories. This setup held under study is a relevant scenario for the Industrial Internet of Things within the industrial sector (IIoT), as the specific characte
Den globala uppvärmningen gör sig ständigt påmind genom extremväder och naturkatastrofer. Vid klimatkonferensen COP21 år 2015 undertecknade i stort sett alla världens länder Parisavtalet med målet att temperaturökningen ska begränsas. För att uppnå Parisavtalets mål ligger en stor del i att länder behöver minska sina utsläpp av växthusgaser. Sverige har minskat sina utsläpp med 35 procent sedan 19Global warming is constantly reminding us of its presence through extreme weather and natural disasters. At the COP21 climate conference in 2015, almost every country in the world signed the Paris Agreement with the aim of limiting temperature increase. The countries need to reduce their greenhouse gas emissions to achieve this. Since 1990, Sweden has reduced its emissions by 35 percent, and in 20
As the scale of single-cell genomics experiments grows into the millions, the computational requirements to process this data are beyond the reach of many. Herein we present Scarf, a modularly designed Python package that seamlessly interoperates with other single-cell toolkits and allows for memory-efficient single-cell analysis of millions of cells on a laptop or low-cost devices like single-boa
This review presents state-of-the-art knowledge and identifies knowledge gaps for future research in the area of exercise-associated modifications of infection susceptibility. Regular moderate-intensity exercise is believed to have beneficial effects on immune health through lowering inflammation intensity and reducing susceptibility to respiratory infections. However, strenuous exercise, as perfo
Interfacial structures on the nanoscale are crucial for a wide field of applications ranging from biological membranes in life sciences through organic solar cells and industrial coatings in soft matter to hard matter structures. The latter include thin film coatings and materials such as magnetic nanoparticles and topological structures like magnetic skyrmions. Advancing such application rests on
A major challenge hampering the industrial and biological exploitation of lipases is the self-limiting effect of the lipolytic reaction. Defying sustained attention throughout history, the influence of lipase catalysed lipolysis on the internal structure of thin triglyceride films has proved elusive. An in-depth understanding of the lipolysis process at the triglycerides/aqueous interface will ass
The structure and function of many proteins are regulated post-translationally through glycan attachment. These glycans, assembled via competing enzymatic reactions, generate diverse glycoform populations - variants sharing a protein backbone but differing in glycan structures. While current analyses often focus on individual glycoforms, we demonstrate that population-level glycoform analysis - in
Polycyclic aromatic hydrocarbons (PAHs) of molecular mass (MM) 302 Da comprise numerous structural isomers that are of high concern for human health. Because of their multiplicity, low abundance in the environment, and limited availability of authentic standards, their occurrence, composition, and environmental health risk remain not well characterized. Here we extend the characterization of MM 30
To improve glycemic control in insulin-dependent diabetes, estimates of the glucose- lowering effect of insulin-the insulin action (IA)-and the dynamics thereof are essential. The current practice relies on generic estimates of the dynamic shape of the IA and rules-of-thumb to assess the total glucose-lowering effect. In this paper we present individualized estimates based on home-monitored data,
Background: International migration has been on the rise over the past few decades and is expected to remain high. Young people make up a significant proportion of those migrating. It has long been known that young people are at greater risk of sexual violence and there is growing evidence that migrants too, are particularly vulnerable. There is a lack of evidence on young migrants’ vulnerability
This deliverable focuses on capturing the current status of testing and validation of services from the RI’s and ENVRI-Hub itself, that are both exposed to EOSC. This means that services are in scope that are shared via the ENVRI Catalogue of Services to the EOSC marketplace. The EOSC validation activities will check the readiness of the ENVRI-FAIR services at the sub-domain and cluster level for
BackgroundA specific eHealth device, a surf tablet, was developed for bridging between advanced in-hospital care and children’s homes. Since little is known about determinators for parental eHealth usage, the study’s aim was to explore if parents’ usage of the device was associated with their eHealth literacy, or their satisfaction with their child’s healthcare or with the specific surf tablet.Met
Polycystic ovary syndrome (PCOS) is a medical condition with important consequences for women’s well-being and reproductive outcomes. Although the etiology of PCOS is not fully understood, there is increasing evidence of both genetic and environmental determinants, including development in early life. We studied a population of 977,637 singleton women born in in Sweden between 1973 and 1995, follo
We propose a consensus definition of "an exaggerated orthostatic pressor response" in subjects in whom systolic blood pressure increases ≥ 20 mmHg when going from supine to standing posture. This definition can be extended for seated to standing measurements. We reserve the term "orthostatic hypertension" for when this pressor response leads to an upright systolic blood pressure ≥ 140 mmHg. We bel
As global food systems are currently presenting great challenges to our environment and our health, diverse new (sustainable) foods and possibilities to integrate these into consumers’ everyday diets are extensively studied. Due to industrialized, standardized food production, approaches from disciplines such as sensory science and consumer psychology play an important role in new product developm
Among different lipid nanoparticle systems, sponge-phase nanoparticles (SPNPs) have recently attracted interest due to their ability to encapsulate large macromolecules along with demonstrated high interfacial activity. The potential application of SPNPs calls for investigations into how buffer conditions affect SPNP structure and interfacial activity. Herein, we systematically investigated how di
Hypothesis: Sponge phase (L3) lipid nanoparticles (L3-NPs) have been shown to have large potential for the encapsulation of biomolecules, such as enzymes, with applications in food and pharmaceutical science. In this study, we introduce new formulations of L3-NPs including the phospholipids dioleoylphosphatidylcholine (DOPC) and dioleoyltrimethylammonium propane (DOTAP). The interaction of these n
This study introduces silicon substrates with a switchable magnetic contrast layer (MCL) for polarized neutron reflectometry (PNR) experiments at the solid–liquid interface to study soft-matter surface layers. During standard neutron reflectometry (NR) experiments on soft-matter samples, structural and compositional information is obtained by collecting experimental data with different isotopic co
Pollination is a critical ecosystem service given its essential role in sustaining food production, while pollinating insects are declining worldwide. Pollination capacity can be estimated through direct indicators characterising pollinator communities. Pollinators need feeding and nesting resources, so their presence can also be estimated through indirect indicators characterising these resources
