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Head computed tomography for prognostication of poor outcome in comatose patients after cardiac arrest and targeted temperature management

INTRODUCTION: A multimodal approach to prognostication of outcome after cardiac arrest (CA) is recommended. Evidence for combinations of methods is low. In this post-hoc analysis we described findings on head computed tomography (CT) after CA. We also examined whether generalised oedema on CT alone or together with the biomarker Neuron-specific enolase (NSE) could predict poor outcome.METHODS: Pat

Autoimmune (type 1) diabetes

Autoimmune (type 1) diabetes mellitus is a chronic disease without a cure. It affects primarily young people but may be diagnosed at any age. Strong genetic susceptibility characterizes the most common form of autoimmune diabetes in children younger than 18 years of age. Autoimmune diabetes is generally assumed to be hereditary, although the majority of patients do not have a family history of aut

Photorefractive and Spectroscopic Properties of Pr:LiNbO3

From the ultraviolet induced absorption, we have found a broad blue band and little involvement of Pr ions in ultraviolet illumination. Ultraviolet excited photoluminescence and the excitation spectra for visible emission were also measured in Pr:LiNbO3. We estimated photovoltaic constant and photoconductivity by measuring photovoltaic current and voltage with different boundary conditions. With u

Hypothermia versus normothermia after out-of-hospital cardiac arrest; the effect on post-intervention serum concentrations of sedatives and analgesics and time to awakening

Background: This study investigated the association of two levels of targeted temperature management (TTM) after out-of-hospital cardiac arrest (OHCA) with administered doses of sedative and analgesic drugs, serum concentrations, and the effect on time to awakening. Methods: This substudy of the TTM2-trial was conducted at three centers in Sweden, with patients randomized to either hypothermia or

Improving a real-time object detector with compact temporal information

Neural networks designed for real-time object detectionhave recently improved significantly, but in practice, look-ing at only a single RGB image at the time may not be ideal.For example, when detecting objects in videos, a foregrounddetection algorithm can be used to obtain compact temporaldata, which can be fed into a neural network alongside RGBimages. We propose an approach for doing this, bas

Housing accessibility and its associations with participation among older adults living with long-standing spinal cord injury

Objectives: To describe the housing situation and aspects of participation among older adults living with long-standing spinal cord injury (SCI) with attention to SCI severity, and to examine whether and how objective housing accessibility (based on objectively measurable criteria) is associated with aspects of participation. Design: Cross-sectional study utilizing the assessment tools Impact on P

Increased pro-inflammatory milieu in combat related PTSD - A new cohort replication study

INTRODUCTION: Several lines of evidence indicate that increased inflammation is associated with Post-Traumatic Stress Disorder (PTSD). We have previously reported that peripheral inflammatory markers are significantly higher in combat-exposed veterans with than without PTSD. This study was designed to replicate these findings in a new study cohort using the same population and recruitment strategi

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1 Responsibility to Respect: Why the Core Company Should Act When Affiliates Infringe Human Rights* Radu Mares  in R. Mares (ed.), The UN Guiding Principles on Business and Human Rights – Foundations and Implementation, Martinus Nijhoff Publishers (Leiden, Boston 2012) pp. 169-192 1. Introduction This chapter discusses the treatment that Professor Ruggie’s Guiding Principles offer for the respons

https://rwi.lu.se/app/uploads/2012/06/Responsibility-to-Respect.pdf - 2026-05-08

Improved executive function and sleep quality in preteens with high-functioning autism following a structured physical activity program

PURPOSE: Children with autism spectrum disorder (ASD) frequently exhibit atypical cognitive profiles, sensory processing challenges, sleep disturbances, and co-occurring psychiatric and somatic conditions. This exploratory prospective study, with a single-arm pre-post design, investigated the effects of a 10-12 weeks structured physical activity program on psychological symptoms, cognitive functio

Validation, Deployment, and Real-World Implementation of a Modular Toolbox for Alzheimer’s Disease Detection and Dementia Risk Reduction : The AD-RIDDLE Project

The Real-World Implementation, Deployment, and Validation of Early Detection Tools and Lifestyle Enhancement (AD-RIDDLE) project, recently launched with the support of the EU Innovative Health Initiative (IHI) public-private partnership and UK Research and Innovation (UKRI), aims to develop, test, and deploy a modular toolbox platform that can reduce existing barriers to the timely detection, and

Stress and circulating cell-free mitochondrial DNA : A systematic review of human studies, physiological considerations, and technical recommendations

Cell-free mitochondrial DNA (cf-mtDNA) is a marker of inflammatory disease and a predictor of mortality, but little is known about cf-mtDNA in relation to psychobiology. A systematic review of the literature reveals that blood cf-mtDNA varies in response to common real-world stressors including psychopathology, acute psychological stress, and exercise. Moreover, cf-mtDNA is inducible within minute

Plasma proenkephalin A 119-159 and dipeptidyl peptidase 3 on admission after cardiac arrest help predict long-term neurological outcome

BACKGROUND: A large proportion of adult survivors of cardiac arrest have a poor neurological outcome. Guidelines recommend multimodal neuro-prognostication no earlier than 72-96 hours after cardiac arrest. There is great interest in earlier prognostic markers, including very early markers at admission. The novel blood biomarkers proenkephalin A 119-159 (penKid), bioactive adrenomedullin (bio-ADM)

Radiofrequency bias correction of magnetization prepared rapid gradient echo MRI at 7.0 Tesla using an external reference in a sequential protocol

At field strengths of 7 T and above, T1-weighted imaging of human brain suffers increasingly from radiofrequency (RF) B1 inhomogeneities. The well-known MP2RAGE (magnetization prepared two rapid acquisition gradient echoes) sequence provides a solution but may not be readily available for all MR systems. Here, we describe the implementation and evaluation of a sequential protocol to obtain normali

Towards a More Inclusive University - Supporting Teachers Through Universal Design for Learning

The diversity among Swedish university students is steadily increasing. The students have different backgrounds, experiences, interests, learning styles and abilities. Also, there are more students with disabilities at Swedish universities, especially invisible disabilities. Teachers need to adapt their teaching and curricula, and can no longer wait to do this until they spot a student with divers

The use of methadone in pediatric cancer pain - a retrospective study from a governmental cancer center in India

Background: The management of cancer-related pain relies on access to opioids. When regular opioids are not tolerated, or are insufficient, methadone is an affordable and effective analgesic. Aim: The aim of the project was to describe the pattern of use and clinical experience of methadone in pediatric cancer pain at a governmental cancer hospital in Hyderabad, one of the four Indian cancer cente

The use of Methadone in adult patients with cancer-pain at a governmental cancer centre in India

Background: Management of cancer-related pain relies on the access to opioids. When regular opioids as morphine are not tolerated or are insufficient, adjuvant opioids as methadone are an affordable and effective analgesic. Aim: The aim of the project was to describe the pattern of use and clinical experiences of methadone in patients with cancer-related pain at a low-resource hospital in Hyderaba

Extreme altitudes during diurnal flights in a nocturnal songbird migrant

Billions of nocturnally migrating songbirds fly across oceans and deserts on their annual journeys. Using multisensor data loggers, we show that great reed warblers (Acrocephalus arundinaceus) regularly prolong their otherwise strictly nocturnal flights into daytime when crossing the Mediterranean Sea and the Sahara Desert. Unexpectedly, when prolonging their flights, they climbed steeply at dawn,

Size and immune function as predictors of predation risk in nestling and newly fledged jackdaws

Prey choice by predators may be based on the potential prey's condition, for example resulting in substandard individuals running a higher risk of being predated. Over 5 years, we studied young jackdaws, Corvus monedula, to determine whether size and innate baseline immune function may predict predation risk by goshawks, Accipiter gentilis, during the nestling and early fledging phases. We measure