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Popular Abstract in Swedish Cancer är ett samlingsnamn för en grupp av sjukdomar som karakteriseras av att cellerna delar sig okontrollerat, till skillnad mot kroppens friska celler. Det leder till att en tumör kan bildas och cellerna kan därifrån sprida sig till andra delar av kroppen och ge upphov till dottertumörer, även kallade metastaser. I Sverige uppskattar man att cirka var tredje person kSmall cell lung carcinoma (SCLC) is a very aggressive solid tumor and is often widely metastasized by the time of diagnosis. Despite good response to the initial chemotherapy, SCLC cells often develop multidrug resistance to conventionally used chemotherapeutic drugs, which cause almost all SCLC tumors to relapse. The 5-year survival rate for patients with limited disease is around 20% while it is

Popular Abstract in Swedish Övervikt är ett av vår tids största hälsoproblem, kanske till och med det största. Det finns de som menar att redan idag utgör övervikt globalt sett en viktigare orsak till sjukdom än undernäring och infektionssjukdomar. Framtidsscenariot beskrivs som alarmerande. Folk kommer att i en tidigare aldrig skådad omfattning insjukna i överviktens följdsjukdomar. Medierna harThe prevalence of overweight and obesity is rising each year not only on a national but also on a global level. The future scenario is troublesome. The media are among the most important social institutions in influencing people’s knowledge, perceptions and actions. The media provide citizens with health messages and contribute thereby to their health development. This dissertation deals with two

BACKGROUND AND OBJECTIVES: The treatment of acquired aplastic anemia (AA) is based on allogeneic bone marrow transplantation (BMT) and immunosuppressive therapy. The aim of this study was to assess the outcome of children and adults with AA treated in the last decade, and to determine whether results have improved in two sequential time periods,1991-1996 and 1997-2002. DESIGN AND METHODS: Two-thou

This article contains a study of how spatial errors and receiver imperfections affect the angle of arrival estimation accuracy for virtual antenna arrays. A virtual antenna array consists of one receiver element whose location is tracked as the element is moved and in this work, linear arrays are studied. If the location of the receiver is tracked using an inertial measurement unit, an interesting

This article considers recent legal developments on undocumented migrant workers, finds the acceptance of international legal standards unsatisfactory and argues that the private law rights derived from the "semi-legal" employment contract between the employer and the undocumented migrant worker generates a solid base for significant legal claims. It further monitors the promotion of the position

Popular AbstractStörre kriser och katastrofer som stormen Gudrun och dess konsekvenser är sannolikt att vänta i framtiden. Det råder dock ovisshet om vilka kriserna kommer att vara och under vilka förutsättningar. Nya och kompletterande vetenskapliga studier och metoder inom kris- och katastrofforskningen måste till för att öka samhällets kunskap om och förmåga att hantera kända och okända hotbildSevere crises and disasters such as the Hurricane Gudrun and their consequences will probably occur in the future. However, there are many uncertainties concerning disasters and their effects. New scientific approaches and methods for crisis and disaster research must be developed to increase the knowledge and ability of societies to manage known and unknown threats. Substantial research on the em

Aerosolsammansättningen i ett renluftsområde i Mellansverige (Velen) har studerats under en årscykel. Aerosolpartiklarna har uppdelats efter aerodynamisk storlek i 7 fraktioner. Varje fraktion från 113 provtagningstillfällen har analyserats m a p svavel och tungmetaller m h a partikelinducerad röntgenstrålning s k PIXE-analys. Resultaten påvisar variationer i ämneskoncentrationer mellan enskilda m

Abstract in UndeterminedThe purpose of this study is to preliminarily evaluate Chile’s energy and climate policy performance historically (1971-2007). The objective is to estimate different indicators in relation to energy and CO2 emission intensities, and identify policy instruments in the light of estimated trends and related structural issues. The methodology is based on a top-down decompositio

Popular Abstract in Swedish Proteinkinas C (PKC) är en familj enzymer (protein som påskyndar cellulära förlopp) bestående av åtminstone 10 medlemmar (isoformer) vilka är involverade i ett flertal cellulära processer. Varje isoform är namngiven med en grekisk bokstav och beroende på olika egenskaper hos enzymerna kan PKC familjen delas in i tre undergrupper, de klassiska (α, βΙ, βΙΙ och γ), de nya Protein kinase C (PKC) is a family of serine/threonine kinases subgrouped into classical (α, βI, βII, γ), novel (δ, ε, η, θ) and atypical (ζ, ι/λ) isoforms. PKC can be activated by phorbol esters, and prolonged treatment of neuroblastoma cells has been shown to induce neuronal differentiation with neurite outgrowth and increased expression of neuronal genes. Here we show that a classical PKCβ isof

Background: Induced hypothermia post-cardiac arrest is neuroprotective in animal experiments, but few high-quality studies have been performed in larger animals with human-like brains. The neuroprotective effect of postischemic hypothermia has recently been questioned in human trials. Our aim is to investigate whether hypothermia post-cardiac arrest confers a benefit compared to normothermia in la

Background: Sedation is routinely administered to critically ill patients to alleviate anxiety, discomfort, and patient-ventilator asynchrony. However, it must be balanced against risks such as delirium and prolonged intensive care stays. This study aimed to investigate the effects of different levels of sedation in critically ill adults. Methods: Systematic review with meta-analysis and trial seq

Retrieving episodic memories often involves reconstructing both their semantic content and the emotional context in which they occurred. However, the neural mechanisms that differentiate these forms of reinstatement remain poorly understood. This event-related potential (ERP) study examines how semantic category and emotional valence are reinstated during memory retrieval.Seventy participants enco

In this section of the European Resuscitation Council Guidelines 2021, key information on the epidemiology and outcome of in and out of hospital cardiac arrest are presented. Key contributions from the European Registry of Cardiac Arrest (EuReCa) collaboration are highlighted. Recommendations are presented to enable health systems to develop registries as a platform for quality improvement and to

This study aims to explore how physicians make sense of and give meaning to their decision-making during obstetric emergencies. Childbirth is considered safe in the wealthiest parts of the world. However, variations in both intervention rates and delivery outcomes have been found between countries and between maternity units of the same country. Interventions can prevent neonatal and maternal morb

Background: Voluntary self-exclusion from gambling is a common but underdeveloped harm reduction tool in the management of gambling problems or gambling disorders. Large-scale, multi-operator, and operator-independent self-exclusion services are needed. A recent nationwide multi-operator self-exclusion service in Sweden (Spelpaus), involving both land- and web-based gambling sites, is promising, b

Static analysis tools play a crucial role in software development by detecting bugs and vulnerabilities. However, running these tools separately from the code editing process often causes developers to switch contexts, which can reduce productivity. Previous work has shown how Reference Attribute Grammars (RAGs) can be used for declarative implementation of competitive tooling for intraprocedural