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Oligodendrocytes are part of the glial cells located in the central nervous system, capable of providing trophic support to neurons and ensheathing their axons. These cells can become dysfunctional under pathologic condition. Rodent and human pluripotent stem cells are inexhaustible sources for producing oligodendrocytes that can be used for disease modeling and cell replacement therapy studies. T

REST is a transcriptional repressor that targets a group of neuronal genes in non-neuronal cells. In embryonic stem (ES) cells, REST has been implicated in controlling the expression of transcription factor genes that are crucial for lineage determination and for maintaining ES cell potential. Here, we asked whether REST directly regulates neural-specifying genes in mouse ES cells using siRNA-medi

This thesis deals with the enforcement of intellectual property rights as an abuse of dominance. In particular after refusal to license a patent, which is essential for a standardized technology. Seeking for injunction relief may in some circumstances violate applicable competition law. The analysis will provide a hint, whereas patent holder who is dominating in particular market can or should be

Uppsatsen syftar till att söka förståelse till varför tvister mellan fackförbund om vem som ska teckna kollektivavtal uppstår. Arbetsmarknadernas parter är i allmänhet ense om att det som regel bör finnas ett kollektivavtal på varje avtalsområde. Kollektivavtalets speciella rättsverkningar gör det viktigt för fackförbunden att vara avtalspart i ett kollektivavtal. Kollektivavtalet sätter i stor utThe aim of this essay is to seek understanding about why conflicts appear between trade unions regarding which one of them should sign the collective agreement in the workplace. The labour market parties are in general in an agreement that there should only be one applicable collective agreement in every area of work. The unique effects of the collective agreement make it crucial for the trade uni

The aim of this qualitative study was to investigate the social identity of students at upper secondary school for physically disabled students. The youths I drew my attention to suffered from severe physical disabilities and therefore received specially adapted education in small classes, but integrated at an ordinary upper secondary school. By "social identity" I mean how the students

The purpose of this study is to evaluate the safety of people located in discotheques in case of fire. A quantitative fire riskanalysis (QRA) for three different types of discotheques is carried out. The analysis is based on performance based codes from which fire protection alternatives are analysed. The results of the quantitative fire riskanalysis are described as risk profiles and average risk

Current trends show that the number of people affected by natural disasters is likely to increase in coming decades. Today, more than half the world's population lives in cities and the number is expected to rise in the future. To make cities safe is therefore vital. Making Cities Resilient is an ongoing global campaign in the area of disaster risk reduction and aims to build resilient cities

Ett antal studier har visat att buller har negativa hälsoeffekter (Barregård et al. 2005; Rosvall et al. 2009; Nilsson, Eriksson & Palmqvist 2009). Exempel på problem som kan uppstå på grund av buller är sömnsvårigheter, hjärt- och kärlsjukdomar, minskad inlärning och reducerad kognitiv förmåga (Berglund, Lindvall & Schwela 1999). Dessa typer av hälsoproblem leder till lidande för den enskNoise has negative health effects according to a number of studies (Barregård et al. 2005; Rosvall et al. 2009; Nilsson, Eriksson & Palmqvist 2009). Example of problems that can occur from exposure to noise is sleeping disturbances, heart diseases, lessened learning and reduced cognitive performance (Berglund, Lindvall & Schwela 1999). This kind of problems cause suffering on a personal le

The purpose of this study is to examine how social service handles incorrect information about them that is spreading on social media. This study is based on a qualitative method. In order to achieve the purpose of this work, the focus has been on the unit of child protection services and seven social workers have been interviewed. The study shows that social workers only handle incorrect informat

When a country liberalizes trade through lowering taxes on imports, it stands before a number of challenges. Recovering lost trade tax revenue is one of them. Cape Verde is one of the countries that are currently negotiating an Economic Partnership Agreement with the EU and studies predict that the tariff reductions resulting from the agreement may have a severe impact on Cape Verde’s government r

IntroductionPost-operative infections obtained from open-wound surgeries constitute an unnecessary load on both healthcare and affected patients. It is well established that increased air cleanliness reduces the number of post-operative infections. Therefore, the ventilation system is important in order to reduce the number of infectious particles in the air during surgery. Ventilation with high a

Weather conditions affect animals in many different ways. Variation in temperature, rainfall, wind, and other environmental variables can have an impact at a range of temporal and spatial scales and at every level from individual behavior to species distributions. The interactions between these variables may be particularly important but are often overlooked. Hence, understanding how animals respo

Massive bird migration across continents and seas is one of the most spectacular phenomena in nature, involving billions of birds annually. In the autumn, most birds on migration are juveniles migrating for the first time while adults are repeating their migrations. Migration syndrome in individual bird migrants involves multiple behavioural, morphological and physiological adaptations, and migrat