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Production of red blood cells relies on proper mitochondrial function, both for their increased energy demands during differentiation and for proper heme and iron homeostasis. Mutations in genes regulating mitochondrial function have been reported in patients with anemia, yet their pathophysiological role often remains unclear. PGC1β is a critical coactivator of mitochondrial biogenesis, with incr
The consecutive binding of two potassium ions to a bis(18-crown-6) analogue of Tröger’s base (BCETB) in water was studied by isothermal titration calorimetry using four different salts, KCl, KI, KSCN, and K2SO4. A counterintuitive result was observed: the enthalpy change associated with the binding of the second ion is more negative than that of the first (ΔH°bind,2 < ΔH°bind,1). This remarkable f
The entire service sector has acknowledged the importance of employee creativity. However, the underlying mechanism due to which employees are engaged in creativity has been relatively unexplored. Moreover, where the banking service sector in advanced countries has realized the potential role of employee creativity for a bank's success, the same was not fully realized in the context of a developin
Light microscopy has been a favorite tool of biological studies for almost a century, recently producing detailed images with exquisite molecular specificity achieving spatial resolution at nanoscale. However, light microscopy is insufficient to provide chemical information as a standalone technique. An increasing amount of evidence demonstrates that optical photothermal infrared microspectroscopy
I syfte att bli mer effektiva och bättre tillgodose kundernas behov växer diverse system och metoder fram. Detta är en genomgående trend inom både handel och serviceindustrin i allmänhet. För att förbättra såväl produktivitet som kvalitet involveras kunderna i allt större utsträckning i serviceprocessen till exempel genom olika former av självbetjäning. Självscanning har utvecklats som ett led i d
Vårt intresse för medarbetarsamtal väcktes vid en gästföreläsning med Jens Ribe som är säljchef för Dell Norden. På denna föreläsning berättade Ribe om sin yrkesroll, sin arbetsvecka osv. och poängterade vikten av att bedriva kontinuerliga medarbetarsamtal för att skapa engagemang, gemensam målbild och skaffa information och skapa en dialog. Han berättade att han genomförde medarbetarsamtal med si
Den här fallstudien undersöker hur Rädda Barnen arbetar opinionsbildande i sin kampanj för att få hem de svenska barnen med föräldrar som har IS-kopplingar från Syrien. Studien har gjorts i syfte att få förståelse för hur Rädda Barnen använder sig av medier för att bedriva sitt kampanjarbete och sätta sig själva och de frågor de bedriver på agendan. Vi har genomfört en studie där vi analyserat fle
This paper aims to examine whether instances of climate injustice faced by the Sami community are acknowledged and given priority in Sweden's efforts to mitigate climate change. The study centers on mining, which has a complex relationship spanning both current issues and historical tensions between Sami interests and governmental ambitions. The paper will take a postcolonial approach, with a
The last mass-extinction event happened over 65 million years ago when an asteroid collided with earth, resulting in the loss of 76% of all species. Scientists now warn that we are on the precipice of a new mass-extinction, the responsibility of which can be placed entirely on one species, the homo sapiens. While some species of birds, bats, and arthropods are especially vulnerable, we are all int
This report evaluates continuing professional development and training for fire offi-cers in the Swedish fire service. A survey about educational and training activities has been carried out amongst Swedish fire services. Some other persons with knowledge in the area has also been interviewed. The results show a big diversity among the interviewed fire services but also some similarities. Discussi
The purpose of this report is to provide knowledge about what factors that contribute to the recruitment and retention of people among volunteer firefighters in small rural communities. The report also aims to provide ideas of how to promote a sustainable retention of volunteers in rural rescue services. The factors have been identified through various study methods with data obtained from a liter
nvestigating the Swedish stock market, we find value stocks to have significantly outperformed growth stocks during the period of 1993 to 2017. As value stocks are found to be riskier during bad states of the economy, the existence of the value premium can be partly attributed to time-varying risk. Value betas are anticyclical, while growth betas exhibit a procyclical pattern. Controlling for time
The purpose of this master’s thesis is to gain in-depth knowledge about how the provision of digital books via the e-book service Biblio functions in Swedish public libraries and how this activity can be understood through the library's mission of promoting the development of a democratic society. To gather the empirical material for this study, we have conducted semi-structured interviews wit
Sustainability reporting has become the primary measure of corporate sustainability in the EU, with increasing awareness among companies about the importance of disclosing sustainability matters. Concurrently, the European Union has enacted several pieces of legislation regarding sustainability reporting, notably the Corporate Sustainability Reporting Directive. While blockchain technology initial
Finished Goods Distribution Network (FGDN) design is an important aspect of Supply Chain Management (SCM), and companies are constantly working towards balancing cost, service level and product quality in the design. At the same time, sustainability has gained an increased focus by stakeholders which has led to both challenges and opportunities in the logistics industry. The FGDN optimization is e
This master thesis investigates the Service Design concept in connection to the Employee-driven Innovation (EDI) field. The Service Design concept entails both a mindset and a toolbox, involving principles such as human-centricity, collaboration and holistic understanding. Previous research has called for more structured approaches to the bottom-up innovation and the EDI process. Furthermore, rese
The vapor–liquid–solid (VLS) mechanism is probably the most versatile method to fabricate semiconductor nanowires and several investigations assume a compositionally homogeneous catalyst particle. In this investigation we address the compositional homogeneity of the catalyst particle during growth of nanowires. Using diffusion calculations, we show that the particle is indeed homogeneous during VL
Objective To systematically review and synthesise the incidence and characteristics of injuries and illnesses among athletes participating in the Olympic, Youth Olympic and Paralympic Games.Design Systematic review and meta-analysis.Data sources PubMed, Embase, CINAHL, Scopus and Web of Science were searched up to 2 July 2024, and Google Scholar, ClinicalTrials.gov and WHO International Clinical T
This longitudinal observational study aimed to determine if ventricular dimensions of the athlete's heart remain balanced and proportional to peak oxygen uptake (VO2peak) following long-term deconditioning in elite athletes. Fourteen mixed-type male athletes (7 soccer, 7 handball players) were prospectively evaluated with cardiac magnetic resonance imaging and cardiopulmonary exercise testing whil
