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There are various ways to classify asthma control; however, no classification is universally accepted. This retrospective analysis compared asthma control as assessed by the Asthma Control Questionnaire (5-item version; ACQ-5), Global Initiative for Asthma (GINA) or Gaining Optimal Asthma Control (GOAL) study criteria. Pooled data at the final study week (n=8,188) from three budesonide/formoterol
Background Mental health interventions should demonstrate an effect on patients' functioning as well as his/her needs, in particular on unmet needs whose assessment depends on the perspective of either the patient or the clinician. However, individual met and unmet needs appear to change over time, qualitatively and quantitatively, raising questions about their sensitivity to change and about the
Insulin secretion is controlled by the beta cell's metabolic state, and the ability of the secretory granules to undergo exocytosis increases during glucose stimulation in a membrane potential-independent fashion. Here, we demonstrate that exocytosis of insulin-containing secretory granules depends on phosphatidylinositol 4-kinase (PI 4-kinase) activity and that inhibition of this enzyme suppresse
From the point of view of each individual’s sense-making, an organization is an emergent property of inter-individual sense-making processes and activities. The organization is a result of emergence from individual sense-making perspectives. A critically informed approach to research involves recognition / understanding of this emergence. Without the recognition of the uniqueness of each particula
In the course of his life’s work, Claudio Ciborra addressed many interesting and complex problem areas of information systems, from management of corporate information infrastructures to organizational learning. However, a unifying theme which permeated his work was an emphasis on recognizing ‘users’ as real human beings, not idealised types. He considered people, leading real, every-day lives; no
The nature of scientific research and the development of scientific software have similarities with processes that follow the agile manifesto: responsiveness to change and collaboration are of the utmost importance. But how well do current scientific software development processes match the practices found in agile development methods, and what are the effects of using agile practices in such proc
Nowadays, organizations pursue their aims in a context of distributed collaboration, creating a need not only for supporting ICT systems, but for a hu-man-centred focus in which individual and group sense-making and learning are supported by appropriate toolsets. We argue that development of such toolsets re-quires an open systems approach. This paper discusses one example: non-competitive benchma
Med en enkätstudie undersöks i detta projekt hur effektivt de berörda anser att de medieetiska systemen ger upprättelse. Här är det värt att nämna att vi då arbetet inleddes bad PO-kansliet om hjälp att distribuera vår enkät till alla dem som stod bakom framgångsrika anmälningar under 2015. På så sätt skulle enkäten kunna genomföras samtidigt som anonymiteten i PO-systemet kunde
The frequent mounting and dismounting the tractor required by many farming operations increases the risk of falls, particularly for older farmers. The present study explored the risk factors related to tractor ingress and egress in older farmers from two countries with a different tradition in terms of safety culture: Sweden and Italy. Eighteen male farmers aged 65 + (8 from Skåne region, southern
BACKGROUND: Highly increased risk of injuries has been noted around the time of cancer diagnosis. Whether there is a similar increase in risk around the diagnosis of cervical cancer and its precursor lesions was unknown.METHODS: We performed a cohort study including 3,016,307 Swedish women that participated in cervical screening during 2001 to 2012. We calculated the incidence rates (IR) of hospit
Purpose of Review: Many aspects of reproduction have been associated with increased blood pressure and impaired glucose metabolism that reveals a subsequent increased risk of cardiovascular disease. The aim of this review is to assess reproductive life factors associated with an increased risk of hypertension and cardiovascular disease, e.g., early life programming, sexual, and reproductive health
BACKGROUND: Proliferative markers are not recommended as prognostic factors for clinical use in breast cancer due to lack of standardization in methodology. However, proliferation is driving several gene expression signatures emphasizing the need for a reliable proliferative marker for clinical use. Studies suggest that cyclin A is a prognostic marker with satisfying reproducibility. We investigat
Aging is associated with complex biological changes that can be accelerated, slowed, or even temporarily reversed by biological and non-biological factors. This article focuses on the link between biological aging, psychological stressors, and mental illness. Rather than comprehensively reviewing this rapidly expanding field, we highlight challenges in this area of research and propose potential s
Doktorsavhandlingen ger inblick i en betydelsefull konsekrerande beslutsprocess inom det svenska konstfältet under perioden 1885–1920. Den analyserar de sociala strukturer som bar fram Nationalmuseums inköpsnämnds och museinämnds årliga beslutsförslag till Kungl. Maj:t om vilka oljemålningar, skapade av vid tiden levande svenska konstnärer, som skulle inlemmas i samlingarna och vilka som skulle exThis dissertation examines the Swedish National Museum of Fine Arts (Nationalmuseum) as a consecrating institution of fine art, between 1885 and 1920. A time influenced by major events such as the First World War, Sweden’s industrial revolution and the advent of universal suffrage. During this period, the production and consumption of the Arts was characterised by rivalry between three fractions,
Background: The CREST model is a prediction model, quantitating the risk of circulatory-etiology death (CED) after cardiac arrest based on variables available at hospital admission, and intend to guide the triage of comatose patients without ST-segment-elevation myocardial infarction after successful cardiopulmonary resuscitation. This study assessed performance of the CREST model in the Target Te
