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Add-on pramipexole for anhedonic depression : study protocol for a randomised controlled trial and open-label follow-up in Lund, Sweden

INTRODUCTION: Many depressed patients do not achieve remission with available treatments. Anhedonia is a common residual symptom associated with treatment resistance as well as low function and quality of life. There are currently no specific and effective treatments for anhedonia. Some trials have shown that dopamine agonist pramipexole is efficacious for treating depression, but more data is nee

AtlFast3: The Next Generation of Fast Simulation in ATLAS

The ATLAS experiment at the Large Hadron Collider has a broad physics programme ranging from precision measurements to direct searches for new particles and new interactions, requiring ever larger and ever more accurate datasets of simulated Monte Carlo events. Detector simulation with Geant4 is accurate but requires significant CPU resources. Over the past decade, ATLAS has developed and utilized

Protocol summary and statistical analysis plan for the Targeted Therapeutic Mild Hypercapnia after Resuscitated Cardiac Arrest (TAME) trial

Background: Targeted therapeutic mild hypercapnia may attenuate brain injury in comatose adults resuscitated from out-of-hospital cardiac arrest. Objective: To describe the study protocol and statistical analysis plan for the Targeted Therapeutic Mild Hypercapnia after Resuscitated Cardiac Arrest (TAME) trial. Design, setting, participants and interventions: TAME is a phase 3, multicentre, paralle

Multiple Representation for Geospatial Linked Data

Current techniques for visualising geospatial Linked Data are limited in terms of multiple representation, which has been studied for decades by cartographers and considered as a prerequisite for deriving appropriate geovisualisation applications. In order to alleviate this issue, this paper presents a work in progress, in which the multiple representation geospatial data are released as Linked Da

Low-dose oral ketamine as a procedural analgesia in pediatric cancer patients undergoing bone marrow aspirations at a resource-limited cancer hospital in India

Aim: Many pediatric cancer patients undergo repeated bone marrow aspirations (BMAs) for diagnostic and treatment evaluation purposes. Full anesthesia is the standard of care during this procedure in high-income countries. At hospitals with low resources in low/middle-income countries many children undergo these painful procedures without sufficient pain relief. This study aimed to evaluate the use

The Subscriptions to Mark’s Gospel and History of Reception

Den här artikeln granskar subskriptionerne på Markusevangeliet i 157 grekiska handskrifter, och noterar deras gradvisa utveckling från att vara identisk med titeln i den tidigaste fasen till att bli mer och mer utarbetad och betydelsefull för tolkningshistorien. Tidigt, vilket återspeglas i titeln, förknippades det andra evangeliet med Markus, känd för att vara Petrus lärjunge och tolk. Under det This article surveys the subscriptions to the Gospel of Mark in 157 Greek manuscripts, noting their gradual development from being identical to the title in the earliest phase to becoming more and more elaborate and significant for the history of interpretation. Early on, as reflected in the title, the Second Gospel was associated with Mark, known to be Peter’s disciple and interpreter. In the fou

Intracoronary Imaging of Proximal Coronary Artery Lesions – A Nationwide Lesion-Level Analysis From SCAAR

Background: Current evidence suggests that use of intracoronary imaging during percutaneous coronary intervention (PCI) of the left main coronary artery (LMCA) reduces mortality. However, there is a scarcity of data on the overall role of intracoronary imaging, particularly in other non-LMCA proximal coronary artery lesions. We aimed to investigate the association of use of intracoronary imaging o

Immune challenge reduces daily activity period in free-living birds for three weeks

Non-lethal infections are common in free-living animals and the associated sickness behaviours can impact crucial life-history trade-offs. However, little is known about the duration and extent of such sickness behaviours in free-living animals, and consequently how they affect life-history decisions. Here, free-living Eurasian blackbirds, Turdus merula, were immune-challenged with lipopolysacchar

Remote Nanoscopy with Infrared Elastic Hyperspectral Lidar

Monitoring insects of different species to understand the factors affecting their diversity and decline is a major challenge. Laser remote sensing and spectroscopy offer promising novel solutions to this. Coherent scattering from thin wing membranes also known as wing interference patterns (WIPs) have recently been demonstrated to be species specific. The colors of WIPs arise due to unique fringy

Phase-matched extreme-ultraviolet frequency-comb generation

Extreme ultraviolet (XUV) laser radiation is commonly produced via high-harmonic generation (HHG) in gases. The lasers that drive this process typically operate at low pulse repetition rates (<100 kHz). Under these operating conditions, the plasma generated by each laser pulse clears the generation volume before the next pulse arrives. Therefore, each laser pulse interacts with fresh plasma-free g

Sovereignty over the Senkaku/Diaoyu islands

I Östkinesiska havet finns en avlägset belägen ögrupp bestående av fem öar och tre karga klippor. Ögruppen utgörs av en nödtorftig vegetation och det förefaller inte finnas något sötvatten. På grund av ögruppens ogästvänliga egenskaper har öarna genom historien ansetts vara av mycket litet ekonomiskt värde och de har sedan urminnes tider, bortsett från en kortare period i början av 1900-talet, varSituated in the East China Sea lays a remotely located island group consisting of five small islands and three barren rocks. The islands sustain scarce vegetation and there’s most likely no fresh water on the islands. Due to their inhospitable character, the islands have historically been considered to be of little economic value and they have since ancient times, apart from a short period during

Nätjournalistik : En explorativ fallstudie av digitala mediers karaktärsdrag på fyra nyhetssajter

Popular Abstract in Swedish Internet har under de senaste tio åren växt från marginalföreteelse till ett populärt och mycket använt medium. Många företeelser och tjänster tar steget över till Internet och bland dessa finns även journalistik. I fokus för denna avhandling står förändringsprocesser för journalistikens villkor, ideal och normer när nyhetsjournalistiken bedrivs på?Internet studerade utDuring the last decade the Internet has become a widely used source of information for the average person and also a publishing tool for media corporations. The transition of journalism from one medium to another is one with important implications as the world wide public consumption of online news grows. This dissertation puts focus on how journalistic content changes when it's published on the W

Efficacy and safety of varenicline and bupropion, in combination and alone, for alcohol use disorder : a randomized, double-blind, placebo-controlled multicentre trial

Background: Alcohol use disorder (AUD) is associated with an enormous burden of disease and cost to society. The dopamine deficiency hypothesis posits that negative reinforcement generated by a low brain dopamine state drives ethanol intake. Here, we evaluated the efficacy and safety of combined administration of two dopamine-enhancing drugs, varenicline (a partial nicotinic acetylcholine receptor

Cancer rehabilitation in clinical practice : a qualitative study exploring contact nurses’ views on prerequisites

Background: Individualized cancer rehabilitation should be an integral part of cancer care. Contact nurses play a key role in identifying patient needs and coordinating evidence-based interventions to support rehabilitation. However, cancer rehabilitation remains marginal in current practice, as contact nurses face challenges due to the lack of systematic processes for assessment, intervention, an

Biocompatability of surfaces for antibody microarrays: Design of macroporous silicon substrates

Antibody microarray is a novel technology with great promise within proteomics. Intense work is under way to evolve this methodology into the high-throughput proteomic research tool needed by the research community. Despite recent advances, there is a growing need for additional highperformance substrates for antibody microarrays as well as for protein arrays in general. In this study, we have suc

Lunchkonsert på Pufendorfinstitutet

Lunchkonsert på Pufendorfinstitutet | The joint faculties of humanities and theology 7 Apr Lunchkonsert på Pufendorfinstitutet 7 April 2026 12:15 to 13:15 Concert Monbijoukvartetten Visst behöver vi något att se fram emot efter påsk? Välkomna till lunchkonsert på Pufendorfinstitutet i Lund. Våra lunchkonserter är öppna för alla och gratis. Ta med er "oprassliga lunch" och lyssna till stråkmusik i

https://www.ht.lu.se/en/the-faculties/whats-on/calendar/event/lunchkonsert-pa-pufendorfinstitutet/ - 2026-04-06

Microsoft Word - SonessonFinal-ProofreadFinal.doc

Microsoft Word - SonessonFinal-ProofreadFinal.doc   1   New Considerations on the Proper Study of Man – and, Marginally, Some Other Animals Göran Sonesson Department of Semiotics & Centre for Cognitive Semiotics, Lund University. Abstract: In order to differentiate the semiotic capacities of animals and human beings we need to understand more exactly what these properties are. Instead of identifyi

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_ccs/SonessonConsiderations.pdf - 2026-05-04

EU Human Rights Due Diligence Webinar Series: An Overview - The Raoul Wallenberg Institute of Human

EU Human Rights Due Diligence Webinar Series: An Overview - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outre

https://rwi.lu.se/blog/eu-human-rights-due-diligence-webinar-series-an-overview/ - 2026-05-04

Summary: Medical

Summary: Medical Summary: Leeches and leechcraft. The professionalization of the art and craft of healing in Sweden during the Middle Ages and Renaissance. Chapter 1: Framework and previous research The arts of healing in the Swedish and Nordic region during the Middle Ages (from the late eleventh century until the Reformation) and the Renaissance is an issue which has previously been studied to a

https://www.uvet.lu.se/media/documents/persons/JohannaBergqvist/Summary_Johanna_Bergqvist_Avhandlingstext.pdf - 2026-05-04