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Serum Iodine and Breast Cancer Risk : A Prospective Nested Case-Control Study Stratified for Selenium Levels

BACKGROUND: Iodine has been suggested to protect against breast cancer, but there are no epidemiologic studies on individual risk. An interesting finding is that in areas where the exposure to both selenium and iodine are high (e.g., Japan), the risk of breast cancer is lower than in areas where selenium is high and iodine low (e.g., United States), or in areas where both are low (e.g., Northern E

Cerebroplacental ratio as predictor of adverse perinatal outcome in the third trimester

Introduction: Fetal growth restriction is associated with adverse perinatal outcome and the clinical management of these pregnancies is a challenge. The aim of this study was to investigate the potential of cerebroplacental ratio (CPR) to predict adverse perinatal outcome in high-risk pregnancies in the third trimester. Another aim was to study whether the CPR has better predictive value than its

Use of two gene panels for prostate cancer diagnosis and patient risk stratification.

Currently, no ideal prostate cancer (PCa) diagnostic or prognostic test is available due to the lack of biomarkers with high sensitivity and specificity. There is an unmet medical need to develop combinations of multiple biomarkers which may have higher accuracy in detection of PCa and stratification of aggressive and indolent cancer patients. The aim of this study was to test two biomarker gene p

The association between plasma proneurotensin and glucose regulation is modified by country of birth

The prevalence of type 2 diabetes (T2D) has increased dramatically in Middle Eastern populations that represent the largest non-European immigrant group in Sweden today. As proneurotensin predicts T2D, the aim of this study was to investigate differences in proneurotensin levels across populations of Middle Eastern and Caucasian origin and to study its associations with indices of glucose regulati

Assessing health-related quality of life (HRQoL) in survivors of out-of-hospital cardiac arrest : A systematic review of patient-reported outcome measures

Aim High quality evidence of out-of-hospital cardiac arrest (OHCA) survivors’ health-related quality of life (HRQoL) can measure the long-term impact of CA. The aim of this study was to critically appraise the evidence of psychometric quality and acceptability of measures used in the assessment of HRQoL in cardiac arrest survivors. Methods Systematic literature searches (2004–2017) and named autho

Characteristics of two-color holographic recording in lithium niobate doped with thulium

We report ultraviolet-induced transient and stable absorption and two-color holographic recording at 514, 633, and 830 nm in thulium doped stoichiometric LiNbO 3 crystal. The gating light at 355 nm increased the diffraction efficiency and sensitivity. We found the optimum gating-recording intensity ratio for maximum diffraction efficiency and weak nonvolatile holographic storage with gating.

Supporting caregivers in nursing homes for Alzheimer’s disease patients : A technological approach to overnight supervision

The reduction of public expenditure and investments in health care provisioning calls for new, sustainable models to transform the increasing aging population and dementia-related diseases incidence from global challenges into new opportunities. In this context, Information and Communication Technologies play a vital role, to both promote aging in place and home management of Patients with Dementi

Resilient Food Supply Chains in the Face of the Russo–Ukrainian War: Harnessing the Power of the Internet of Things

The current war in Ukraine has severely disrupted global food supply chains due to the significant decline in the production of grain commodities, of which Ukraine and Russia are major global suppliers. This creates problems in today’s globalised food systems. In particular, a number of countries are heavily dependent on food imports from Ukraine and/or Russia, particularly some developing nations

Simulation of near-infrared light propagation through the thorax of a neonate : Addressing the optimisation of source and detector positions for measuring lung oxygen content in preterm infants

Gas in scattering media absorption spectroscopy shortly called GASMAS, is a tunable diode laser spectroscopic technique developed for the measurement of gas present in turbid media. The technique relies on the sharp and specific absorption lines of gases which enables sensitive measurements of gas concentrations in the presence of a scattering solid medium with much broader absorption features. Th

Using Cards to Facilitate Conversations About Wishes and Priorities of Patients in Palliative Care

To avoid discomfort, health care professionals may hesitate to pursue conversations about end of life with patients. Certain tools have the potential to facilitate smoother conversations in this matter. The objective was to explore the experiences of patients in palliative care in using statement cards to talk about their wishes and priorities. Forty-six cards with statements of wishes and priorit

Symptom relief during last week of life in neurological diseases

Objectives: The aim of this study was to investigate symptom prevalence, symptom relief, and palliative care indicators during the last week of life, comparing them for patients with motor neuron disease (MND), central nervous system tumors (CNS tumor), and other neurological diseases (OND). Material & Methods: Data were obtained from the Swedish Register for Palliative Care, which documents c

Comorbidity between pain and mental illness - Evidence of a bidirectional relationship

Background: Pain from various locations in the body and mental illness are common and the comorbidity between the two is well-known although the temporal relationship remains to be determined. Our aim was to follow patients over time to study if pain (here dorsalgia/abdominal pain) or fibromyalgia lead to an increased risk of developing mental illness (here depression/anxiety) and/or the reverse,

Socio-geographical disparities in cardiometabolic multimorbidity in Sweden : an Intersectional Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (I-MAIHDA)

Background: Mapping social and geographical disparities in health outcomes helps to identify vulnerable groups that should be targeted for intervention. This study aims to assess the disparities in cardiometabolic multimorbidity, the presence of at least two cardiometabolic diseases (CMD), including type 2 diabetes, heart disease, and stroke, among middle-aged adults across socio-geographical inte

The Utility of Maternal Blood S100B in Women with Suspected or Established Preeclampsia—A Systematic Review

Purpose: Preeclampsia is a serious pregnancy complication without curative treatment. The central nervous system (CNS) is affected in severe cases of preeclampsia. Until now, no biomarker or other predictive method has been established for predicting severe CNS injury, including the development of eclampsia and/or long-term complications. In this systematic review, we aimed to investigate the asso

Don’t ask, don’t tell (DADT) : under-recognition of breathlessness in clinical care—a national survey

Introduction The recognition of breathlessness in clinical practice appears suboptimal, despite its prevalence and impact. This study aimed to explore the content of clinical conversations about breathlessness and patients’ level of self-reported openness when discussing their breathlessness. Methods A cross-sectional, online survey of Australian adults (≥18 years) stratified to the 2016 National