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The genome sequence of the Brown Argus, Aricia agestis (Denis & Schiffermüller, 1775)

We present genome assemblies from two male Aricia agestis specimens (the Brown Argus; Arthropoda; Insecta; Lepidoptera; Lycaenidae). The genome sequences are 435.3 and 437.4 megabases in span. Each assembly is scaffolded into 23 chromosomal pseudomolecules, including the Z sex chromosome. The mitochondrial genomes were assembled and are 15.47 and 15.45 kilobases in length. Gene annotation of these

Sepsis mimics among presumed sepsis patients at intensive care admission: a retrospective observational study

BackgroundDiagnosing sepsis remains a challenge because of the lack of gold-standard diagnostics. Since there are no simple, broadly accepted criteria for infection, there is a risk of misclassifying sepsis patients (sepsis mimics) among patients with organ failure. The main objective of this study was to investigate the proportion of non-infected patients (sepsis mimics) in ICU patients with pres

A Data-driven Riccati Equation

Certainty equivalence adaptive controllers are analysed using a “data-driven Riccati equation”, corresponding to the model-free Bellman equation used in Q-learning. The equation depends quadratically on data correlation matrices. This makes it possible to derive simple sufficient conditions for stability and robustness to unmodeled dynamics in adaptive systems. The paper is concluded by short rema

Foraging on the wing for fish while migrating over changing landscapes : traveling behaviors vary with available aquatic habitat for Caspian terns

Background: Birds that forage while covering distance during migration should adjust traveling behaviors as the availability of foraging habitat changes. Particularly, the behavior of those species that depend on bodies of water to find food yet manage to migrate over changing landscapes may be limited by the substantial variation in feeding opportunities along the route. Methods: Using GPS tracki

Knowledge and attitudes to cardiopulmonary resuscitation (CPR) - a cross-sectional population survey in Sweden

Aim of the studyRates of bystander CPR are increasing, yet mortality after out-of-hospital cardiac arrest (OHCA) remains high. The aim of this survey was to explore public knowledge and attitudes to CPR. Our hypotheses were that recent CPR training (< 5 years) would be associated with a high-quality response in a case vignette of OHCA with agonal breathing, and associated with an interest to becom

Diffraction-limited light collection: Promises and challenges of a 50 m ELT

Programmes driving ELT design are discussed. The nature and evolution of circum-stellar shells and planetary discs are attractive, while the small angular sizes place basic properties, asymmetry and warps, beyond VLT capability. An ELT is neeed to reveal the conversion processes shell - disc - planets, planetary systems, Earth-like planets, habitability and life signatures. Formation and evolution

Accurate prediction of B-form/A-form DNA conformation propensity from primary sequence : A machine learning and free energy handshake

DNA carries the genetic code of life, with different conformations associated with different biological functions. Predicting the conformation of DNA from its primary sequence, although desirable, is a challenging problem owing to the polymorphic nature of DNA. We have deployed a host of machine learning algorithms, including the popular state-of-the-art LightGBM (a gradient boosting model), for b

Crisis and Public Support for the Euro, 1999–2014

This contribution analyses the evolution of public support for the single European currency, the euro, from 1990 to 2014 for a 12-country sample of the euro area (EA-12), focusing on the most recent period of the financial and sovereign debt crisis, starting in 2008. We find that citizens’ support for the euro on average was marginally reduced during the first six years of the crisis, and that sup

Influence of AFIR's charging station spacing requirement on heavy-duty vehicle electrification rate

Den snabba utvecklingen av elektrifiering av vägtransporter i Sverige kräver forskningsbaserade beslut om placeringen av laddinfrastruktur. Europeiska unionens (EU) nya förordning för infrastruktur för alternativa bränslen (AFIR) specificerar det maximala tillåtna avståndet mellan offentliga snabbladdningsstationer (FCS) för tunga lastbilar längs det transeuropeiska transportnätverket (TEN-T). EffThe rapid progression of the electrification of road transport in Sweden requires effective research based decisions on the location of charging infrastructure. The new European Union (EU) regulation for alternative fuel infrastructure (AFIR) specifies the maximum allowed distance between public fast-charging stations (FCSs) for heavy-duty trucks along the Trans-European Transport Network (TEN-T).

Cell cycle regulatory proteins and miRNAs in premalignant lesions and breast cancer

Popular Abstract in Swedish Cancer är ett laddat ord, och för de flesta av oss är cancern inte längre bort än hos en nära släkting eller vän. Trots den gemensamma benämningen, är cancer är inte bara en sjukdom, utan ca 200 olika som alla har gemensamt att cellerna börjar dela sig okontrollerat. Cancer är väldigt vanligt och uppskattningsvis kommer var tredje person att drabbas av cancer under sin Early diagnosis and reliable prognosis and treatment prediction of breast cancer will ultimately lead to a decreased mortality rate. This can be achieved by identification of prognostic and treatment predictive biomarkers, and by understanding the mechanisms behind early changes in the breast. The cell cycle is a closely controlled process, involving multiple components with regulation on several

Investigation of the two-phase flow field of the GTX100 compressor inlet during off-line washing

A modern gas turbine compressor, with its highly aerodynamically loaded blades, is sensitive to changes in profile shape and to surface roughness. Fouling is inevitable, despite highly efficient filtration systems. The remedy to this problem is washing. There are two different approaches, online or off-line washing. The off-line wash is the most effective one, whilst on-line washing only prolongs