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The interferon inducible protein TRIM22 has been identified as a p53 target gene, with possible involvement in proliferation and differentiation of leukaemia cells. Here, the expression levels of TRIM22 during haematopoietic differentiation are characterised. Expression of TRIM22 correlates inversely to differentiation, as TRIM22 is highly expressed in CD34(+) human bone marrow progenitor cells, b

Background and aims: In the elderly, balance and walking impairments are assumed to play an important role in causing falls. We have assessed prospectively the predictive ability of health, function and balance variables regarding falls and their location. Methods: Falls which occurred during one year in a random sample of 307 women aged 75 years and over (mean 80.8 years, response rate 74.5%) liv

The previous round-robin (RR) study on clothing evaporative resistance (Ret) has shown that the repeatability and reproducibility of clothing Ret measurements on sweating manikins were rather low. To further examine and enhance the measurement accuracy, a new strict but feasible test protocol was proposed and thoroughly examined in a new round-robin test. Eight laboratories participated in this st

Aim To describe the relative impact on survival of the delay from estimated time of collapse to call for an ambulance among patients who suffer from a bystander witnessed out of hospital cardiac arrest of a cardiac aetiology. Methods A majority of all ambulance organizations in Sweden (covering 85% of Sweden inhabitants) participate in a National survey of out of hospital cardiac arrest. Results I

The European Border and Coast Guard was launched on October 6th, 2016. It was established through Regulation 2016/1624 and replaces the European Agency for the Management of Operational Cooperation at the External Borders of the Member States. The Agency is more known as Frontex. The objective with this thesis is to examine two problems in Regulation 2016/1624 that was addressed at the negotiatio

Online courses have become common in health sciences education. This learning environment can be designed using different approaches to support student learning. To further develop online environment, it is important to understand how students perceive working and learning online. The aim of this study is to identify aspects influencing students' learning processes and their adaptation to self-dir

Inflammation is a physiological response that may go uncontrolled and thereby develop in a chronic way. This seems to happen in many common diseases of autoimmune, degenerative, or allergic character. Rheumatoid arthritis (RA) is by definition a chronic disease with an autoimmune inflammatory attack on diarthrodial cartilaginous joints. The development of new treatment neutralizing cytokines invol

We sought to evaluate the experiences and knowledge of health care providers in Sweden regarding female genital cutting (FGC) as a health issue. Questionnaires (n = 2,707) were sent to providers in four major cities in Sweden and evaluated by means of descriptive statistics. Twenty-eight percent (n = 769/2,707) responded, of whom 60% had seen such patients. Seven providers, including 2 pediatricia

This Bachelor’s degree project investigates how to create a modular chair system. It should let the consumer combine different parts to create a chair that fits their home, style and needs. The focus is on how a low number of parts can be used in different ways to create differentcombinations. It should also be easy to replace and recycle all parts when needed. This document shows the full design

Importance: Better understanding of patients' attitudes toward deprescribing specific medications will inform future deprescribing interventions. Objective: To investigate older adults' attitudes toward deprescribing by investigating which medications they would like to have deprescribed, the reasons why, and patient factors associated with interest in deprescribing. Design, Setting, and Participa

Global health is a multidisciplinary field focused on improving health and achieving equity in health for all people worldwide. The COVID-19 pandemic left a profound and lasting impact on global mental health, triggering a surge in anxiety, depression, and stress-related disorders across all age groups and regions. As the world transitions into the post-COVID period, mental health has emerged as a