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SingleRespondentReport_Main Strategic Research Environment questionnaire 2012Vinnova Sida 1 av 30 Based on our initial application (2009) the main priorities set in 2012 were the following for the strategic research area Epidemiology for Health (EpiHealth): - to further develop an infrastructure for EpiHealth linking Lund University (LU) and Uppsala University (UU). - to promote excellence in epid

https://www.epihealth.lu.se/sites/epihealth.lu.se/files/verksamhetsuppfoljning_2012.pdf - 2026-06-08

Nanoscience for Sustainable Energy HEINER LINKE AND LARS SAMUELSON | NANOLUND Nanoscience is the art of understanding and using the new physical behavior exhibited by very small material components – and it offers a wealth of opportunities to help achieve a sustainable energy supply. This is one of the aims of NanoLund, the Center for Nanoscience at Lund University with more than 200 scientists at

https://www.nano.lu.se/sites/nano.lu.se/files/nanoscience_for_sustainable_energy_2015.pdf - 2026-06-08

We study the mapping and reporting of climate-related risks among firms listed on the NasdaqOMX stock exchange in Stockholm in four goods producing industries. Our study contains two parts: i) a study of the firms’ external communication through their annual reports, sustainability reports and webpages, and ii) a follow-up survey to the top management team. The survey contains quantitative questioWe study the mapping and reporting of climate-related risks among firms listed on the NasdaqOMX stock exchange in Stockholm in four goods-producing industries. Our study contains two parts: (i) a study of the firms’ external communication through their annual reports, sustainability reports and webpages, and (ii) a follow-up survey of the top management team. The survey contains quantitative quest

This paper argues that in many contexts where effectiveness analysis such as benefit-cost analysis and cost-effectiveness analysis is used, we have good reason to think that some benefits or costs are incommensurable invalue such that neither can be determined to be better than the other, although they cannot be determined to beequally good either. Two responses to such value incommensurability ar

BACKGROUND: Polycystic ovary syndrome (PCOS) has previously been associated with several comorbidities that may have shared genetic, epigenetic, developmental or environmental origins. PCOS may be influenced by prenatal androgen excess, poor intrauterine or childhood environmental factors, childhood obesity and learned health risk behaviors. We analyzed the association between PCOS and several rel

Even though hematopoietic stem cells (HSC) are characterized by their ability to self-renew and differentiate, they primarily reside in quiescence. Despite the immense importance of this quiescent state, its maintenance and regulation is still incompletely understood. Schlafen2 (Slfn2) is a cytoplasmic protein known to be involved in cell proliferation, differentiation, quiescence, interferon resp

Background: The transcription factor signal transducer and activator of transcription 3 (STAT3) is implicated in cancer drug resistance, metastasis, and immunosuppression and has been identified as a promising therapeutic target for new anticancer drugs. Myeloid-derived suppressor cells (MDSCs) play a major role in the suppression of antitumor immunity and STAT3 is involved in the accumulation, ge

Most common breast cancer susceptibility variants have been identified through genome-wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease1. We conducted a GWAS using 21,468 ER-negative cases and 100,594 controls combined with 18,908 BRCA1 mutation carriers (9,414 with breast cancer), all of European origin. We identified independent associations at P < 5 × 10-8

Purpose: This article hypothesizes that designing cancer therapies based on the organ specific toxicity of the normal tissue of the organ from which the tumors originated could be worthwhile. A prerequisite for successful therapy is that the individual can recover from damage done to the organ or cells.Results: Therapeutic examples are given for lymphoma, kidney cancer, melanoma and leukemia.Concl

Plasma analysis by mass spectrometry-based proteomics remains a challenge due to its large dynamic range of 10 orders in magnitude. We created a methodology for protein identification known as Wise MS Transfer (WiMT). Melanoma plasma samples from biobank archives were directly analyzed using simple sample preparation. WiMT is based on MS1 features between several MS runs together with custom prote

Background: Informed consent is a prerequisite for patients included in clinical trials. Trial design, inclusion criteria and legal requirements are increasingly complex. This complexity challenges design and delivery of written and oral trial information to ensure understandable information. To evaluate the level of concordance between patients' and informing physicians' assessments regarding pat

Objective Neighbourhood deprivation is a recognised predictor of coronary heart disease (CHD). The overall aim was to investigate if accumulated exposure to neighbourhood deprivation resulted in higher odds of CHD. Design This is a longitudinal cohort study. Models based on repeated assessments of neighbourhood deprivation as well as single-point-in-time assessments were compared. Setting Sweden.

The risk of pancreatic cancer (PC) is increased in melanoma-prone families but the causal relationship between germline CDKN2A mutations and PC risk is uncertain, suggesting the existence of non-CDKN2A factors. One genetic possibility involves patients having mutations in multiple high-risk PC-related genes; however, no systematic examination has yet been conducted. We used next-generation sequenc

Hereditary syndromes causing colorectal cancer include both polyposis and non-polyposis syndromes. Overlapping phenotypes between the syndromes have been recognized and this make targeted molecular testing for single genes less favorable, instead there is a gaining interest for multi-gene panel-based approaches detecting both SNVs, indels and CNVs in the same assay. We applied a panel including 19

Failure of the human heart to maintain sufficient output of blood for the demands of the body, heart failure, is a common condition with high mortality even with modern therapeutic alternatives. To identify molecular determinants of mortality in patients with new-onset heart failure, we performed a meta-analysis of genome-wide association studies and follow-up genotyping in independent populations

FÖRSÄTTSSIDA STYRDOKUMENT Riktlinjer vid misstanke om oredlighet i forskning som stöds av Public Health Services, USA Typ av styrdokument: Riktlinjer Definition av typen av styrdokument: Riktlinjer fastställer hur någon ska eller bör handla inom det område riktlinjerna omfattar. En ska- regel ska följas medan en bör-regel mer har karaktären av en stark rekommendation som innebär att man undantagsv

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2026-05/riktlinjer-vid-misstanke-om-oredlighet-i-forskning-som-stods-av-public-health-services-%20USA.pdf - 2026-06-08

Botswana’s reputation as a beacon of fiscal prudence in resource-rich economies faces new challenges. Yet recent pressures – rising debt, declining surpluses, and fiscal volatility – raise questions about the long-term sustainability of this model. This thesis examines how Botswana’s fiscal capacity has shaped its ability to manage natural resource wealth between 1990 and 2022. Drawing on a compos

We use a closed-loop algorithm to accurately program hafnium zirconium oxide (HZO) ferroelectric tunnel junctions (FTJs) to arbitrary chosen target conductance values. The key enabler is suppression of conductance growth. We have identified two different mechanisms contributing to the total conductance of FTJs. By controlling both, we demonstrated an up to threefold increase of the usable conducta