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A hallmark of adult hematopoiesis is the continuous replacement of blood cells with limited lifespans. While active hematopoietic stem cell (HSC) contribution to multilineage hematopoiesis is the foundation of clinical HSC transplantation, recent reports have questioned the physiological contribution of HSCs to normal/steady-state adult hematopoiesis. Here, we use inducible lineage tracing from ge

Purpose: This article hypothesizes that designing cancer therapies based on the organ specific toxicity of the normal tissue of the organ from which the tumors originated could be worthwhile. A prerequisite for successful therapy is that the individual can recover from damage done to the organ or cells.Results: Therapeutic examples are given for lymphoma, kidney cancer, melanoma and leukemia.Concl

Plasma analysis by mass spectrometry-based proteomics remains a challenge due to its large dynamic range of 10 orders in magnitude. We created a methodology for protein identification known as Wise MS Transfer (WiMT). Melanoma plasma samples from biobank archives were directly analyzed using simple sample preparation. WiMT is based on MS1 features between several MS runs together with custom prote

Type 2 diabetes is a multifactorial disease with multiple underlying aetiologies. To address this heterogeneity a previous study clustered people with diabetes into five diabetes subtypes. The aim of the current study is to investigate the aetiology of these clusters by comparing their molecular signatures. In three independent cohorts, in total 15,940 individuals were clustered based on five clin

Background: Informed consent is a prerequisite for patients included in clinical trials. Trial design, inclusion criteria and legal requirements are increasingly complex. This complexity challenges design and delivery of written and oral trial information to ensure understandable information. To evaluate the level of concordance between patients' and informing physicians' assessments regarding pat

Objective Neighbourhood deprivation is a recognised predictor of coronary heart disease (CHD). The overall aim was to investigate if accumulated exposure to neighbourhood deprivation resulted in higher odds of CHD. Design This is a longitudinal cohort study. Models based on repeated assessments of neighbourhood deprivation as well as single-point-in-time assessments were compared. Setting Sweden.

The risk of pancreatic cancer (PC) is increased in melanoma-prone families but the causal relationship between germline CDKN2A mutations and PC risk is uncertain, suggesting the existence of non-CDKN2A factors. One genetic possibility involves patients having mutations in multiple high-risk PC-related genes; however, no systematic examination has yet been conducted. We used next-generation sequenc

It is a public health priority to identify the adverse and non-adverse associations between pharmaceutical medications and cancer. We search for and evaluate associations between all prescribed medications and longitudinal cancer risk in participants of the Swedish Cancer Register (N = 9,014,975). We associated 552 different medications with incident cancer risk (any, breast, colon, and prostate)

Hereditary syndromes causing colorectal cancer include both polyposis and non-polyposis syndromes. Overlapping phenotypes between the syndromes have been recognized and this make targeted molecular testing for single genes less favorable, instead there is a gaining interest for multi-gene panel-based approaches detecting both SNVs, indels and CNVs in the same assay. We applied a panel including 19

Failure of the human heart to maintain sufficient output of blood for the demands of the body, heart failure, is a common condition with high mortality even with modern therapeutic alternatives. To identify molecular determinants of mortality in patients with new-onset heart failure, we performed a meta-analysis of genome-wide association studies and follow-up genotyping in independent populations

This study examines how national healthcare initiatives focused on person-centered care are put into practice within Sweden's healthcare system. It analyses how these national policies are represented and implemented in accreditation documents across six Swedish regions—Skåne, Västra Götaland, Jönköping, Halland, Kronoberg, and Östergötland. The research uses qualitative document analysis to e

We use a closed-loop algorithm to accurately program hafnium zirconium oxide (HZO) ferroelectric tunnel junctions (FTJs) to arbitrary chosen target conductance values. The key enabler is suppression of conductance growth. We have identified two different mechanisms contributing to the total conductance of FTJs. By controlling both, we demonstrated an up to threefold increase of the usable conducta

19 juni 2025 11:15 till 11:45 | Utställning Välkommen på en visning där engagerande berättelser och samtal om konst blandas med joller och barnskrik. Barnvagnsvisningarna på Skissernas Museum är den perfekta aktiviteten för dig som är föräldraledig eller är barnvakt åt en bebis i åldern 0–15 månader. På de här visningarna blandas engagerande berättelser och samtal om konst med joller och barnskrik

https://www.lu.se/evenemang/barnvagnsvisning-pa-skissernas-museum-2 - 2026-06-08

https://www.lu.se/evenemang/musikhogskolan-i-malmos-symfoniorkester-med-maria-itkonen-dirigent-och-jacob-aurell-slagverk-malmo - 2026-06-08

EUA REPORT Transition to University Autonomy in Kazakhstan State of play of university governance and recommendations for the reform process 2018 1 2 Transition to University Autonomy in Kazakhstan State of play of university governance and recommendations for the reform process Report by the European University Association For the TRUNAK project Work package 1 Preparation Deliverables 1.1 and 1.2

https://www.cmes.lu.se/sites/cmes.lu.se/files/2021-01/trunak_eua_report_wp1_final.pdf - 2026-06-08

Kursplan Introduktion till organisation och ledarskap TEORI FLT30 Kursplan KURSENS NAMN: Introduktion till organisation och ledarskap KURSKOD: FLT30 POÄNG: 10 FASTSTÄLLD: Godkänd av YH ledningsgrupp 2022-03-07 REVIDERAD: -- GÄLLER FÖR: Utbildningsomgång YH01518-2021-1 och YH01518- 2021-2, YH01518-2023-1, YH01518-2023-2, YH01518-2023-3 TYP AV KURS OCH DESS INPLACERING I UTBILDNINGSSYSTEMET: Kursen

https://www.flyg.lth.se/sites/flyg.lth.se/files/2026-04/Kursplan%20Introduktion%20till%20organisation%20och%20ledarskap%20-%20FLT30,%2010%20yhp%20T26.pdf - 2026-06-08

Microsoft Word - Staffan Skerfving.docx 1       Järnålderns Helgö Vad var det egentligen? Staffan Skerfving 2013-05-13 Institutionen för Arkeologi Lunds Universitet ARKA12 2013-05-13 2     Iron age Helgö – what was it really? Abstract Helgö is a small island in Lake Mälaren in central Sweden. It has a strategic geographic position at a narrow strait, close to an important crossing of two important

https://www.ark.lu.se/media/utbildning/dokument/kurser/ARKA12/20131/Staffan_Skerfving.pdf - 2026-06-05