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Minimal structural perturbation of Histatin 5 in crowded environments : Insights from small-angle X-ray scattering, dynamic light scattering, and computer simulations

The structure and dynamics of intrinsically disordered proteins (IDPs) are malleable to solution conditions. Considerable effort has been devoted to understanding the effects of molecular crowding on these properties. Polymer-based crowders, such as polyethylene glycol (PEG) and Ficoll®, are commonly used to simulate the intracellular environment by replicating the high concentration of macromolec

Risk and prognosis of colorectal cancer following bacteraemia with Streptococcus bovis-Streptococcus equinus complex : A Swedish nationwide retrospective cohort study

There is a positive association between bacteraemia with Streptococcus bovis-Streptococcus equinus complex (SBSEC) and colorectal cancer (CRC). However, the relationship between the timing of SBSEC bacteraemia and CRC is not well-established. Associations with other gastrointestinal cancers have also been suggested. Using national registries, we retrospectively examined the incidence of CRC and ot

Structure and morphology of vesicular dispersions based on novel phosphatidyl glucose and phosphatidyl choline with different acyl chains

Hypothesis: Phospholipids are widely used in food and pharmacological formulations. However, these typically suffer from limitations such as low colloidal stability. Promising stability has been observed for vesicles based on phosphatidylglucose (P-Glu), but fundamental knowledge on this lipid is missing and those observations were made using P-Glu containing mixed acyl groups. The acyl groups are

Different ways of diagnosing selective glomerular hypofiltration syndromes such as shrunken pore syndrome and the associated increase in mortality

BackgroundIn 2015, a selective decrease in the glomerular filtration of middle-sized molecules such as cystatin C compared to small molecules such as creatinine was first described and tentatively termed “Shrunken pore syndrome.” Numerous studies have thereafter found an association between this syndrome (defined by a low eGFRcystatin C to eGFRcreatinine ratio) and mortality and morbidity. In 2023

Eva Nylander

Bibliotekarie Kontaktinformation E-post: eva [dot] nylander [at] ub [dot] lu [dot] se Telefon: +46 46 222 91 70 Mobil: +46 72 545 67 67Organisation Stab Hämtställe: 19 WebbplatsEva Nylanders profil i Lunds universitets forskningsportalAndra roller Docent Avdelningen för bokhistoria Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filtrera efter typ AllaArtikel i tidskriftBok

https://www.lub.lu.se/internt/eva-nylander - 2026-06-06

Prospects for improved glomerular filtration rate estimation based on creatinine—results from a transnational multicentre study

Background The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine equation is routinely used to assess renal function but exhibits varying accuracy depending on patient characteristics and clinical presentation. The overall aim of the present study was to assess if and to what extent glomerular filtration rate (GFR) estimation based on creatinine can be improved.MethodsIn a cro

Enhancing mitochondrial function in vivo rescues MDS-like anemia induced by pRb deficiency

Erythropoiesis is intimately coupled to cell division, and deletion of the cell cycle regulator retinoblastoma protein (pRb) causes anemia in mice. Erythroid-specific deletion of pRb has been found to result in inefficient erythropoiesis because of deregulated coordination of cell cycle exit and mitochondrial biogenesis. However, the pathophysiology remains to be fully described, and further chara

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

Genome-wide association studies (GWAS) identified the chromosome 15q25.1 locus as a leading susceptibility region for lung cancer. However, the pathogenic pathways, through which susceptibility SNPs within chromosome 15q25.1 affects lung cancer risk, have not been explored. We analyzed three cohorts with GWAS data consisting 42,901 individuals and lung expression quantitative trait loci (eQTL) dat

Gap Distance Between Pearl Chains in Acoustic Manipulation

We present a theory to compute the stable gap (interparticle) distance between particle chains collected in the pressure node of an acoustic standing wave. The primary and secondary acoustic radiation forces are the two competing forces that act on the particles during the particle chain formation. The stable equilibrium distance between two chains is reached when both forces are in balance. Most

Train delays due to trackwork in Sweden

Only well-maintained railway systems can function without severe interruptions. However,maintenance activities can themselves cause train delays if they conflict with trainmovements. Trackwork refers to maintenance performed on a railway track. This studyaims to investigate the effect of trackwork on train delays in Sweden. It presents a logisticregression analysis based on more than 225,000 plannOnly well-maintained railway systems can function without severe interruptions. However, maintenance activities can themselves cause train delays if they conflict with train movements. Trackwork refers to maintenance performed on a railway track. This study aims to investigate the effect of trackwork on train delays in Sweden. It presents a logistic regression analysis based on more than 225,000 p

Improving commuter train punctuality using lead indicators

Train delays are often monitored using lag indicators of achieved punctuality levels, but indicators can also be used proactively as lead indicators to help reach a certain level of punctuality. In this paper, two lead indicators – the share of delayed dwell times and the share of delayed run times – are formulated and tested on Swedish commuter train data for the years 2001-2020. Results show tha

Performance of creatinine-based equations to estimate glomerular filtration rate in White and Black populations in Europe, Brazil and Africa

Background: A new Chronic Kidney Disease Epidemiology Collaboration equation without the race variable has been recently proposed (CKD-EPIAS). This equation has neither been validated outside USA nor compared with the new European Kidney Function Consortium (EKFC) and Lund-Malmö Revised (LMREV) equations, developed in European cohorts. Methods: Standardized creatinine and measured glomerular filtr

miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients.

Background:The microRNA-205 (miR-205) has been shown to be deregulated in prostate cancer (PCa). Here we continue to investigate the prognostic and therapeutic potential of this microRNA.Methods:The expression of miR-205 is measured by qRT-PCR and in situ hybridisation in a well-documented PCa cohort. An AGO2-based RIP-Chip assay is used to identify targets that are verified with western blots, lu

Ferruform

Ferruform | Akademikerföreningen på Scania och TRATON Hoppa till huvudinnehåll Öppna sökruta Öppna Huvudmeny Sök på saco.se Bli medlem Därför är vi med GDPR och hantering personuppgifter Engagera dig Kontaktpersonrollen Skyddsombudsrollen Ledamot i styrelsen Ledamot i valberedningen Revisorsrollen Frågor vi driver Färdriktning Arbetsmiljö Lön, förmåner & kompetensutveckling Transformation Lön Öka

https://www.saco.se/fortroendevald/lokalt-fackligt-arbete/lokala-akademikerforeningar/privat/akademikerforeningen-pa-scania/kontakt/kontaktpersoner/test/ferruform/ - 2026-06-07

Meat consumption in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohorts: results 24-hour dietary recalls

Objective: To evaluate meat intake patterns in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohorts. Design and setting: 24-Hour dietary recalls were assessed within the framework of a prospective cohort study in 27 centres across 10 European countries by means of standardised computer-assisted interviews. Subjects: In total, 22 924 women and 13 031 men aged 35-74 years.

Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.

Diamond-Blackfan anaemia (DBA) is a rare congenital disease causing severe anaemia and progressive bone marrow failure. The majority of patients carry mutations in ribosomal proteins, which leads to depletion of erythroid progenitors in the bone marrow. As many as 40% of all DBA patients receive glucocorticoids to alleviate their anaemia. However, despite their use in DBA treatment for more than h

Edwards peter

Wake-Up Call: The Environmental and Human Health Implications of Bio transported PCBs in the Sub-arctic of North America Wake-Up Call: The Environmental and Human Health Implications of Bio transported PCBs in the Sub-arctic of North America By Peter Edwards Bachelor of Science University of British Columbia 2000 Kämnärsväg 4:1123 S-226 45 Lund Sweden A thesis submitted in partial fulfillment of t

https://www.lumes.lu.se/sites/lumes.lu.se/files/edwards_peter.pdf - 2026-06-07

Larsson maria

Master Thesis Lumes 1999/2000 LundUniversity Application of "Best Possible Technology" in Sweden with respect to Heating Systems in Buildings A study initiated by the Environmental Unit at Skanska Teknik AB By: Maria Larsson Richertsgatan 16 41260 Göteborg Sweden 031-126392 mala@hem.utfors.se Scientific Supervisor: Prof. em. Bo Adamson Lund Institute of Technology Department of Building Science Bo

https://www.lumes.lu.se/sites/lumes.lu.se/files/larsson_maria.pdf - 2026-06-07