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In-situ SEM study of fracture of an ultrathin Al-foil-modelling of the fracture processes

Fracture behavior of an ultra thin Aluminium foil was studied. For very short crack lengths, fracture has been followed in the scanner electronic microscope (SEM) with a tensile stage. A single edge notched tension specimen was used. Crack length and applied load during the crack growth were measured. These results have been used to calculate fracture strength using linear elastic fracture mechani

Phenotypic characterization of acoustically enriched extracellular vesicles from pathogen-activated platelets

Extracellular vesicles (EVs) are derived from the membrane of platelets and released in the circulation upon activation or injury. Analogous to the parent cell, platelet derived EVs play an important role in hemostasis and immune responses by transfer of bioactive cargo from the parent cells. Platelet activation and release of EVs increases in several pathological inflammatory diseases, such as se

Isolation and Purification of Mycobacterial Extracellular Vesicles

Bacterial extracellular vesicles (EVs) contain numerous active substances that mediate bacterial interactions with their host and with other microbes. Best defined are the EVs from Gram-negative bacteria that have been shown to deliver virulence factors, modulate the immune responses, mediate antibiotic resistance, and also inhibit competitive microbes. Due to the complex cell wall structures of G

Body mass index is negatively associated with telomere length : A collaborative cross-sectional meta-analysis of 87 observational studies

Background: Even before the onset of age-related diseases, obesity might be a contributing factor to the cumulative burden of oxidative stress and chronic inflammation throughout the life course. Obesity may therefore contribute to accelerated shortening of telomeres. Consequently, obese persons are more likely to have shorter telomeres, but the association between body mass index (BMI) and leukoc

Chains of risk for alcohol use disorder : Mediators of exposure to neighborhood deprivation in early and middle childhood

Our goal was to test a cascade model to identify developmental pathways, or chains of risk, from neighborhood deprivation in childhood to alcohol use disorder (AUD) in young adulthood. Using Swedish general population data, we examined whether exposure to neighborhood deprivation during early and middle childhood was associated with indicators of social functioning in adolescence and emerging adul

Levels of Narrativity in Scandinavian Bronze Age Petroglyphs

In Europe, Scandinavia holds the largest concentration of rock art (i.e. petroglyphs), created c. 5000–first century BC, many of them showing figurative and seemingly narrative representations. In this paper, we will discuss possible narratological approaches applied to these images. We might reasonably distinguish between three levels of pictorial narrativity: representations of (i) single eventsIn Europe, Scandinavia holds the largest concentration of rock art (i.e. petroglyphs), created c. 5000–first century bc, many of them showing figurative and seemingly narrative representations. In this paper, we will discuss possible narratological approaches applied to these images. We might reasonably distinguish between three levels of pictorial narrativity: representations of (i) single events

Is familial risk for depression confounded by individual and familial socioeconomic factors and neighborhood environmental factors? A 7-year follow-up study in Sweden

Family history of depression is an important risk factor for depression. The aim of this study was to examine whether the effect of family history of depression is confounded by individual and familial socioeconomic factors (i.e., country of origin, educational attainment, family income and mobility) and neighborhood environmental factors (i.e., neighborhood deprivation and neighborhood social cap

Innovation Policies and New Regional Growth Paths : A Place-Based System Failure Framework

Fundamental and enduring changes brought about by recurrent economic and financial crises, the digital revolution and ongoing globalisation processes of production and innovation activities are posing major challenges for regional and national economies to renew their industrial structures and develop innovations that break existing development trajectories. This calls for new innovation policy ap

Peatland dynamics in response to past and potential future climate change : A regional modelling approach

En majoritet av de nordliga torvmarkerna utvecklades under holocen som ett resultat av en positiv massbalans mellan nettoprimärproduktion och heterotrofa nedbrytningshastigheter. Sedan dess har de lagrat stora mängder kol i terrestra ekosystem. En betydande del av dessa områden sammanfaller också med regioner med underliggande permafrost och uppvisar olika ackumulationsmönster av torv. Således, föThe majority of the northern peatlands developed during the Holocene as a result of a positive mass balance between net primary productivity (NPP) and heterotrophic decomposition rates. Over that time they have sequestered a huge amount of carbon in terrestrial ecosystems. A significant proportion of these areas also coincides with areas underlain with permafrost and shows a diverse range of peat

Is accessibility to dental care facilities in rural areas associated with number of teeth in elderly residents?

Given that public transportation networks are less developed in rural than in urban areas, a lack of accessibility to dental care facilities could be a barrier to routine dental checkups. Thus, we hypothesized that the distance to the dental care facilities is a risk factor for tooth loss. The aim of this study was to test whether there is an association between the distance to dental care facilit

Familial Associations in Testicular Cancer with Other Cancers

Familial risks for testicular cancer (TC) are among the highest of all cancers. However, data are limited for histological types of TC and for possible familial associations of TC with other cancers. We used the nationwide Swedish Family-Cancer Database for years 1958 to 2015 to analyse familial relative risks (RR) for 11,138 TC patients when first-degree relatives were diagnosed with TC or other

Professional blinders? The novel as an eye-opener in organizational analysis

Scholarly textbooks often follow a logic where suitable empirical cases are selected to illustrate the theoretical and analytical points that we as scholars want to make. But what would happen if we would do the opposite: build a textbook on a novel written by a novelist for such purpose and let the theories explain the actions and emotions of fictional characters? In this article, we share and re

Nationwide paediatric cohort study of a protective association between allergy and complicated appendicitis

BACKGROUND: In a nationwide cohort the potentially protective association between allergy and complicated appendicitis was analysed, and the influence of seasonal antigens, antihistamine treatment, and timing of allergy onset assessed.METHODS: Some 1 112 571 children born between 2000 and 2010 were followed from birth until the end of 2014. A cross-sectional analysis of appendicitis cases, with co

Is Long-Term Exposure to Air Pollution Associated with Episodic Memory? A Longitudinal Study from Northern Sweden

Associations between long-Term exposure to ambient air pollution and cognitive function have been observed in a few longitudinal studies. Our aim was to investigate the association between long-Term exposure to air pollution and episodic memory, a marker of early cognitive decline. We used data from the Betula study in Northern Sweden, and included participants 60 to 85 of age at inclusion, 1,469

Is the effect of body mass index on hypertension modified by the elevation? A cross-sectional study of rural areas in Japan

Obesity is an established independent risk factor for developing hypertension. A recent study showed that the effect of obesity on hypertension varies by the elevation of the residence area. Thus, we hypothesized that the interaction effect of body mass index (BMI) and elevation has a significant association with hypertension. The first aim of this cross-sectional study was to examine whether BMI

The added value of a mobile application of Community Case Management on referral, re-consultation and hospitalization rates of children aged under 5 years in two districts in Northern Malawi : Study protocol for a pragmatic, stepped-wedge cluster-randomized controlled trial

Background: There is evidence to suggest that frontline community health workers in Malawi are under-referring children to higher-level facilities. Integrating a digitized version of paper-based methods of Community Case Management (CCM) could strengthen delivery, increasing urgent referral rates and preventing unnecessary re-consultations and hospital admissions. This trial aims to evaluate the a

Neighborhood deprivation and inequities in coronary heart disease among patients with diabetes mellitus: A multilevel study of 334,000 patients.

We used multilevel models to investigate whether the odds of coronary heart disease (CHD) is higher in patients with diabetes mellitus (DM) living in deprived neighborhoods versus those living in wealthy neighborhoods. The Swedish nationwide prescription register was used to identify 334,000 patients aged 30 years and older with DM. The OR of CHD was significantly higher among patients with DM liv

Human rights obligations of armed groups exercise control over territory and perform governmental functions

An increasing amount of people living under the control of armed groups begged the question on the human rights obligations by armed groups in situation of protracted armed conflict. Traditionally, international human rights treaties only impose obligations on states. This raises concerns about the protection vacuum as well as accountability of the armed groups. A new phenomenon also emerged where

Housing reconstruction in disaster recovery: a study of fishing communities post-tsunami in chennai, India.

Disaster recovery after the Indian Ocean tsunami in 2004 led to a number of challenges and raised issues concerning land rights and housing reconstruction in the affected countries. This paper discusses the resistance to relocation of fishing communities in Chennai, India. Qualitative research methods were used to describe complexities in the debate between the state and the community regarding re