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It has been suggested that mitochondrial dysfunction and DNA damage are involved in lymphomagenesis. Increased copy number of mitochondrial DNA (mtDNA) as a compensatory mechanism of mitochondrial dysfunction previously has been associated with B-cell lymphomas, in particular chronic lymphocytic leukemia (CLL). However, current evidence is limited and based on a relatively small number of cases. U
The relationship between community structure and growth and pH tolerance of a soil bacterial community was studied after liming in a reciprocal inoculum study. An unlimed (UL) humus soil with a pH of 4.0 was fumigated with chloroform for 4 h, after which < 1 % of the initial bacterial activity remained. Half of the fumigated soil was experimentally limed (EL) to a pH of 7.6. Both the UL and the EL
Deficient soluble fiber intake has been suggested to dysregulate the immune response either directly or through alterations of the microbial composition in the gut.
Families where the mother has an intellectual disability need support to counteract possible detrimental life circumstances for the children involved. The aim of this study was to describe social and healthcare professionals' experiences of providing support for families with maternal intellectual disability and specifically focused on if and how they believed the support practices benefited the c
The hidden Markov model (HMM) has been widely used in regime classification and turning point detection for econometric series after the decisive paper by Hamilton (Econometrica 57(2):357–384, 1989). The present paper will show that when using HMM to detect the turning point in cyclical series, the accuracy of the detection will be influenced when the data are exposed to high volatilities or combi
Non-steroid anti-inflammatory drugs (NSAIDs) are frequently occurring in sludge and waters from sewage treatment plants (STPs). Sludge obtained from sewage treatment is often applied as a fertilizer in agriculture and not many studies about the uptake of pharmaceuticals into crops can be found. In this paper, we present a greenhouse experiment to study the presence of four NSAIDs (naproxen, ketopr
Power spectrum analysis of heart rate variability (HRV) may provide insight into the mental state of the animal held in restricted specific experimental conditions. Determining inter-beat-interval (IBI) variations is one way to measure changes in autonomic nervous system (ANS) activity in horses. An imbalance between the sympathetic and parasympathetic nervous system can indicate pain or stress, f
Seaweed can be anaerobically digested for the production of energy-rich methane. However, the use of seaweed digestate as a fertilizer may be restricted because of the high heavy metal content especially cadmium. Reducing the concentration of heavy metals in the digestate will enable its use as a fertilizer. In this laboratory-scale study, the potential of seaweed and its leachate in the productio
Several prospective studies have shown a moderate positive association between increasing circulating insulin-like growth factor-I (IGF-I) levels and colorectal cancer risk. However, the associations were often statistically nonsignificant, and the relationship of cancer risk with IGF-I's major binding protein, IGFBP-3, showed major discrepancies between studies. We investigated the association of
Insights into oceanographic environmental conditions such as paleoproductivity, deep-water temperatures, salinity, ice volumes, and nutrient cycling have all been obtained from geochemical analyses of biomineralized carbonate of marine organisms. However, we cannot fully understand geochemical proxy incorporation and the fidelity of such in species until we better understand fundamental aspects of
We aimed to validate genetic variants as instruments for insulin resistance and secretion, to characterise their association with intermediate phenotypes, and to investigate their role in T2D risk among normal-weight, overweight and obese individuals.We investigated the association of genetic scores with euglycaemic-hyperinsulinaemic clamp- and OGTT-based measures of insulin resistance and secreti
Risk factors for acute myocardial infarction (AMI) are known to cluster and to be differently distributed in men and women. The aim of this study was to sex-specifically explore clusters of acknowledged AMI risk factors by factor analysis, and to study whether such clusters are associated with left ventricular hypertrophy (LVH), used as a subclinical measure of CHD.
The press-fit condylar (PFC) cruciate-retaining total knee prosthesis is well documented in the literature. In 1997, a modification of the femoral component was introduced, and the prosthesis was renamed PFC-Sigma. The alteration may influence the migratory and rotational pattern of the tibial component and thus long-time survival rate. In this radiostereometric analysis, we found that the micromo
The aim of the present study was to investigate the distribution of suicide attempts across the depressive episodes in suicides and controls with a severe depression. A blind record evaluation was performed of 100 suicide victims and matched controls admitted to the Department of Psychiatry between 1956 and 1969 and monitored to 2006. There was a similar number of episodes in suicides and controls
The objective was to investigate prevalence, estimate risk factors, and antenatal suspicion of abnormally invasive placenta (AIP) associated with laparotomy in women in the Nordic countries.
Signal transducer and activator of transcription 3 (STAT3) is known to be involved in the progression of prostate cancer (PCa) and is a key factor in drug resistance and tumor immunoescape. As a result, it represents a promising target for PCa therapy. We studied the effects of the STAT3 inhibitor galiellalactone (GL) on tumor growth and metastatic spread in vitro and in vivo. The effect of GL on
Chemical risks of consumer goods are a rather new concern in society. These risks are usually based on sythetic chemicals and man-made, often imperceptible and potentially devastating. These risks are reliant on knowledge claims and experiences as basis for risk judgments since, for example, chemical properties, threshold values and exposure are part of defining the risk. But risks are also define
In Vietnam, practical settlement of criminal cases tends to indicate that incorrect judgments still exist that naturally prejudices the legitimate rights and interests of citizens, including the right to have defense counsel. This results from various causes, of which the overlapping and contradictory nature of the laws is one. This dissertation focuses on examining the contents of the applicable
Biodiversity offsets have been proposed as part of the EU 2020 Biodiversity Strategy in order to achieve 'no-net-loss' of biodiversity. However, there is a growing number of criticisms towards the use of offsets, particularly from a political ecology approach. Drawing from analysis of key EU documents and working reports, this thesis examines whether the proposed use of biodiversity offset
This paper investigates the barriers that immigrant woman entrepreneurs (IWEs) face in starting their firms, and the strategies they use to overcome them. The study interviewed seven IWEs in Skåne, Sweden to gain a deeper understanding of their experiences. The study uses a theoretical framework that focuses on gender, family, culture, social and human capital and the institutional barriers as the
