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Background and aims:Heart transplantation (HT) constitutes the ultimate treatment choice for end-stage heart failure. Following HT, patients require life-long immunosuppressive treatment to prevent allograft rejection. Although survival has steadily increased over the last few decades, issues related to under- and over-immunosuppression remain common and continue to represent one of the most impor
Niganda phichai Pellinen, sp. n., is described from northern Thailand. The new species is diagnosed and illustrated, including details of the genitalia and DNA sequencing. Variability in the male genitalia of Niganda radialis Gaede is reviewed, and notes are presented on the facies of female N. radialis
To investigate, within the first 2 years of diagnosis with rheumatoid arthritis (RA), associations between disease-related measures and cardiovascular disease (CVD) and mortality in patients with RA onset before and after 65 years of age.
This thesis consists of three different essays, all of which have arisen from a practical problem. In the first essay, “Technical efficiency and ownership: The case of booking centers in the Swedish Taxi Market” the purpose is to examine the question of competition on an equal basis between privately and publicly owned booking centers in the Swedish taxi market. One way to answer this question is
Purpose: To assess safety, tolerability, pharmacokinetics and clinical activity of HuMax-EGFr in patients with SCCHN. Patients and methods: Twenty-eight patients with SCCHN were enrolled. The study comprised a single-dose escalation part for assessment of safety issues followed by a repeat dose extension including 4 weekly infusions at the same doses. Efficacy and metabolic response were evaluated
Pseudomonas aeruginosa is the dominant pathogen causing chronic lung infections in patients with cystic fibrosis (CF). After an initial phase characterized by intermittent colonizations, a chronic infection is established upon conversion of P. aeruginosa from the non-mucoid to the mucoid, alginate-overproducing phenotype. During the chronic infection the isolation of both mucoid and non-mucoid iso
To prospectively study the prevalence of Lyme arthritis, 100 consecutive patients referred to a rheumatology out-patient clinic and 115 patients with a classified rheumatological disease were included. Individuals seropositive for antibody against the Borrelia burgdorferi sensu lato complex were examined for clinical signs or a history of Lyme borreliosis. Positive titres against B. burgdorferi s.
Background: The purpose of this study was to evaluate if a positron emission tomography (PET) scan, 6 weeks post radiotherapy (RT), adequately selects patients in whom a neck node dissection can be omitted. Primary endpoints were isolated neck recurrences and overall survival (OS). Methods: 105 patients, mainly with oropharyngeal human papilloma virus (HPV) positive tumors, with a positive PET sca
Cladribine has single-drug activity in acute myeloid leukaemia (AML), and may enhance the formation of the active metabolite (ara-CTP) of cytosine arabinoside (ara-C). To evaluate the feasibility of adding intermittent cladribine to intermediate-dose ara-C (1 g/m(2)/2 h) b.i.d. for 4 d with idarubicin (CCI), we performed a 2:1 randomized phase II trial in AML patients aged over 60 years. Primary e
Stigma has been identified as one of the most important obstacles for a successful integration of people with mental illness into the society. Research about stigma has shown negative attitudes among the public towards people with mental illness. Studies so far have, however, put little emphasis on how these negative attitudes are perceived by the mentally ill persons. The aim of the present study
Natural gas/diesel dual-fuel combustion is a novel technique that offers high thermal efficiency and reduced emissions without requiring extensive hardware changes or complex aftertreatment systems. Previous study conducted on the same setup has shown that increasing the diesel mass split ratio (SR) between two injections and advancing the start of first injection (SOI1) improved NOx, HC emissions
Loss of biodiversity is an immediate threat to the planet and if no actions are taken it is expected to accelerate. The highest species richness on smaller scale is found in semi-natural temperate grasslands, with one of the documented records from Stora Alvaret on Öland, Sweden. The area is protected under the Natura 2000-network and Länstyrelsen Kalmar are responsible for monitoring while local
The purpose of this study was to develop an understanding of how the perception of stress for HR-professionals within staffing- and recruitment, might differentiate when working more or less from home. An additional ambition was to develop an understanding of how the work characteristics, job-demand, control and support, could have an impact on the above association. To examine this, an explorator
Hjälpfrågor Värdeteori, F2 1. Vad är distinktionen mellan predikativt och attributivt värde? 2. Varför anser Geach att distinktionen i (1) utgör en utmaning för finalt värde? 3. Hur skiljer sig Geachs syn på attributivt värde från den syn som Thomson har? 4. Hur bemöts Geachs utmaning i litteraturen? 5. Vilken var Geachs syn på värdet av abstrakta entiteter som sakförhållanden? 6.
https://www.fil.lu.se/media/utbildning/dokument/kurser/FPRA21/20151/hjlpfrgor_2.pdf - 2026-07-21
Den snabba tekniska utvecklingen rörande artificiell intelligens öppnar upp för många juridiska frågor, inte minst vad rör upphovsrätt. I syfte att kunna gene-rera material med hjälp av artificiell intelligens krävs det att tillhandahållare av AI har tillgång till stora mängder data, för att kunna träna upp dessa till att producera resultat som efterliknar mänskliga verk. Frågan som därigenom uppsThe rapid technological development of artificial intelligence gives rise to nu-merous legal issues, particularly concerning intellectual property. For artificial intelligence to generate material, it must be trained on human-created works to produce results that resemble such. This process requires access to large vol-umes of data, often sourced from the internet and large databases. The ques-tio
Fractures pose a significant burden on society, making prevention strategies important. One approach is to increase physical activity (PA), which may enhance bone mass and muscle strength, thereby lowering fracture risk. A total of 3476 children who began 1st grade (mean age 7 years) between 1998 and 2012 in four Swedish schools were included. The intervention group was 1328 children from one scho
Functionalized computed tomography (CT) in combination with labelled cells is virtually non-existent due to the limited sensitivity of X-ray-absorption-based imaging, but would be highly desirable to realise cell tracking studies in entire organisms. In this study we applied in-line free propagation X-ray phase-contrast CT (XPCT) in an allergic asthma mouse model to assess structural changes as we
