Filetype
Background: Regardless of the indisputable benefits of insulin therapy, initiating insulin for newly diagnosed type-1 children with diabetes might be intimidating for parents. This study assesses the experience, fears, barriers and adherence to insulin use among the parents of early-diagnosed children with diabetes. Methods: A cross-sectional online survey was utilized for data collection from 218
Background. Pain is common in Parkinson's disease (PD) and impairs quality of life. The King's PD pain questionnaire (KPPQ) is a standardized, reliable, and valid self-administered questionnaire for screening of pain in PD. We developed a linguistically validated German version of the KPPQ and applied it to a cohort with fluctuating PD. Methods. The interculturally adapted German translation was p
Non-structural protein 3 (Nsp3) is the largest protein encoded by the coronavirus (CoV) genome. It consists of multiple domains that perform critical functions during the viral life cycle. CoV-Y is the most C-terminal domain of Nsp3, and it exhibits evolutionary conservation across diverse CoVs; however, the exact biological function of CoV-Y remains unclear. Here, we determined the crystal struct
Previous studies have shown that police assaults reduce trust in the police among the group affected by the incidents. As the phenomenon of plural policing emerges and the actors in policing become intertwined, blurring the boundaries between them, analysis of the impact of security guards’ actions becomes warranted. This paper investigates the impact of two security guard incidents on trust in th
The species of Siderus Kaye present in French Guiana are listed and detailed with notes on male territorial behavior and the plants at which adults feed. In total, seven species were recorded: Siderus leucophaeus (Hübner); Siderus parvinotus Kaye (first record from French Guiana); Siderus athymbra (Hewitson); Siderus diringeri Faynel, Robbins & Fåhraeus sp. nov.; Siderus bisignatus Faynel, Ram
1. 1. Endogenous phospholipase A2 (PLA2) inhibitors in human plasma and in plasma from the hedgehog (Erinaceus europaeus) were demonstrated. 2. 2. The PLA2 activity increased 45-fold in human plasma when a PLA2 binding factor was removed. Furthermore, two peaks of PLA2 inhibitory activity were found after DEAE-chromatography. 3. 3. High levels of PLA2 inhibitory activity was found in plasma from t
Wang Q, Pantzar N. Jeppsson B, Weström BR, Karlsson BW. Increased intestinal marker absorption due to regional permeability changes and decreased intestinal transit during sepsis in the rat. Scand J Gastroenterol 1994;29:1001-1008. Background: The intestinal barrier properties are impaired during inflammation and sepsis, but the mechanisms behind this are unknown and were therefore investigated du
Polycrystalline cubic boron nitride (pcBN) is a very promising tool material for turning martensitic stainless steels at high cutting speeds (vc > 200 m/min). The competitive advantage of pcBN over cemented carbide increases as the cutting speed is increased. Changing the speed might lead to a shift in the wear balance and hence the knowledge about tool wear below vc = 200 m/min might not be appli
This paper draws on critical discourse analysis to examine how health and physical education (HPE) curricula from Sweden, Norway, South Africa, Australia, and New Zealand may influence possibilities for the enactment of social justice in schools. The findings highlight the presence of social justice intentions across the five curricula as related to embodied movement experiences, social cohesion,
This study examined driver failure and traffic conflict using a driving simulator during lane-change scenarios on a 2+1 road, focusing on differences between day and night conditions. Data on driver failure status and driving behavior were captured through a survey. The study also evaluated driver performance and electrodermal activity. The findings revealed that nighttime lane changes had a short
Introduction Anorectal malformations (ARMs) are complex congenital anomalies of the anorectal region, oftentimes also affecting the genitourinary system. Although successful surgical correction can often be achieved in the neonatal period, many children will experience functional problems in the long term. The European Reference Network for rare and complex urogenital conditions (eUROGEN) assemble
Drug company funding can create conflicts of interest that compromise the integrity of patient organizations, a problem studied primarily in Western Europe and North America. To address this research gap, we conducted a case study in Poland, a Central European country. Between 2012 and 2020, 33 companies reported payments worth €13 729 644 to 273 patient organizations in Poland. The funding was hi
Adult neurogenesis continues throughout life but declines dramatically with age and in neurodegenerative disorders such as Alzheimer's disease. In parallel, microglia become activated resulting in chronic inflammation in the aged brain. A unique type of microglia, suggested to support neurogenesis, exists in the subventricular zone (SVZ), but little is known how they are affected by aging. We anal
The paper identifies three interconnected scales of global politics in Artificial Intelligence (AI) and healthcare. It provides a multilevel framework for policy makers to situate hybrid-human AI collaborations in healthcare within broader global political concerns.
Social entrepreneurship integrates a focus on tackling social issues with economically sustainable business activities, thereby also presenting a new form of private sector engagement in development work. This mixed-method case study contributes to the nascent body of academic literature by examining the role and accessibility of the social entrepreneurship support ecosystem in the context of Colo
This study examines the relationship between four dimensions of psychological capital (PsyCap) and nascent entrepreneurial activity among Ukrainian refugees residing in European host countries. Specifically, it analyzes how internally and externally sourced fear of failure moderates this relationship, focusing on the psychological and emotional barriers that may limit refugees’ entrepreneurial
Canopy cover is widely recognized as an important factor for mitigating extreme heat events in cities. The EU Regulation on Nature Restoration further emphasizes this, requiring urban areas to increase their canopy cover. However, the vertical complexity of urban trees is another significant factor for cooling, and moreover beneficial for biodiversity. The purpose of this study is to investigate t
In academic and political discourse, Vivir Bien has emerged as an Indigenous vision of wellbeing in harmony with community and nature. This thesis examines how ecological and economic priorities are negotiated in the pursuit of Vivir Bien within the Indigenous Autonomy of Charagua Iyambae, Bolivia. Focusing on the Guaraní cosmovision of Yaiko Kavi Päve (‘to live well’), the study explores how loca
Future hydrological droughts in reservoir-regulated regions remain uncertain due to the complex interactions between climate change and reservoir operation. Existing studies usually rely on simplified empirical representations of historical reservoir operations and rarely consider the role of optimal reservoir operation policies. Here, we used the upper Hanjiang River basin (UHRB) in China as a ca
Integrating sustainability into the core business strategy remains a significant challenge faced by many companies. This study explores how an integrated sustainability strategy (ISS) unfolds by examining the organizational and cross-functional conditions that enable or constrain the implementation, the operational tensions that emerge along this process, and the dynamic managerial capabilities (D
