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The energy and mass measurements of jets are crucial tasks for the Large Hadron Collider experiments. This paper presents a new calibration method to simultaneously calibrate these quantities for large-radius jets measured with the ATLAS detector using a deep neural network (DNN). To address the specificities of the calibration problem, special loss functions and training procedures are employed,
This thesis investigates superfluidity in exotic phases of ultracold bosonic gases, namely self-bound droplets, mixed bubbles, and dipolar supersolids. We investigated these systems analytically and numerically using an extended Gross-Pitaevskii and Bogoliubov-de Gennes formalism. The dissertation offers six chapters, providing the necessary derivations to build the required background and underst
BACKGROUND: In the era of rising carbapenem resistance, we aimed to investigate the change in mortality rate and positivity of carbapenemase genes in Acinetobacter baumannii.METHODS: Preferred Reporting Items for Systematic Review (PRISMA) guidelines were adopted in this systematic review. Our literature search included the Cochrane Library, Pubmed, Scopus, Web of Science, Medline, Tubitak TR Dizi
This research introduces a novel Energy Management approach, named CIRLEM, aiming to enhance the smartness of buildings by focusing on technical systems operations, environmental variations, and occupants' needs. Deployed in a simulated environment using Building Performance Simulation and Python integration, the study evaluates CIRLEM's performance under future extreme cold weather scenarios, emp
Even though it is primarily used in blends with gasoline, neat ethanol is considered an excellent fuel for spark-ignition engines, as demonstrated by its widespread use as a transportation fuel in Brazil. The use of biologically produced alcohols in neat form has the potential to displace larger amounts of fossil fuels, compared to using them solely as oxygenate blend components. Consequently, fur
Geopolitical, health and economic events have led to an accumulated surge in energy prices in the UK at the beginning of the 2020s. In response, studies and media reports show that households have had to reduce the running of their heating systems to cut their energy bills. However, there is limited research on the impact of this context on indoor thermal conditions and occupants’ ability to meet
A “clean-label” gluten-free bread (GFB) was developed by replacing the commonly used hydrocolloid additive, methylcellulose, with an aqueous flaxseed slurry (FSS), known for its structure-forming properties, at 3 or 4.5 % levels into GFB formulations; for further nutritional improvement of GFB, the inclusion of 5 or 10 % roasted-sprouted lentil flour (SLF) was also investigated. FSS and SLF additi
In geoengineering, such as oil and gas production, geological CO2 storage, geothermal projects, and environmental remediation, a detailed understanding of the hydraulic and mechanical properties of sandstone properties is crucial. Traditional theories on the hydraulic and mechanical behavior of rocks rely on bulk measurements from boundary sensors, which fail to capture complex heterogeneity in st
Bioelectronics holds great potential as therapeutics, but introducing conductive structures within the body poses great challenges. While implanted rigid and substrate-bound electrodes often result in inflammation and scarring in vivo, they outperform the in situ-formed, more biocompatible electrodes by providing superior control over electrode geometry. For example, one of the most researched met
The racemic 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[1-(pyridin-2-yl)ethyl]propanamide, 1, has previously been identified as a potent but unselective inhibitor of diphtheria toxin-like ADP-ribosyltransferase 3 (ARTD3). Herein we describe synthesis and evaluation of 55 compounds in this class. It was found that the stereochemistry is of great importance for both selectivity and potency and that subs
Background and Aim: Full-thickness biopsies of the intestinal wall may be used to study and assess damage to the neurons of the enteric nervous system (ENS), that is, enteric neuropathy. The ENS is difficult to examine due to its localization deep in the intestinal wall and its organization with several connections in diverging directions. Histological sections used in clinical practice only visua
The Brazilian Savanna (Cerrado) is the second-largest South American biome that corresponds to almost two-third of the national agricultural production. Extensive agricultural-driven land-use changes have significantly altered the landscape, causing increased soil erosion. Furthermore, projections of climate change effects on the Cerrado raise concerns about the potential exacerbation of soil loss
This paper presents the results of the 2022 Groundwater Time Series Modelling Challenge, where 15 teams from different institutes applied various data-driven models to simulate hydraulic-head time series at four monitoring wells. Three of the wells were located in Europe and one was located in the USA in different hydrogeological settings in temperate, continental, or subarctic climates. Participa
South Korean cultivators share features with counterparts in both the global south and north. This combination of traits has produced a diversity of sources that underpin a food sovereignty movement. A case study of t’ojong, or native, seed activism illustrates how local systems of meaning and particular constellations of interests make food sovereignty appealing to a broad coalition of farmers, c
Context. Neutron-capture elements represent an important nucleosynthetic channel in the study of the Galactic chemical evolution of stellar populations. For stellar populations behind significant extinction, such as those in the Galactic centre and along the Galactic plane, abundance analyses based on near-infrared (NIR) spectra are necessary. Previously, spectral lines from the neutron-capture el
Aromatic side chains (phenylalanine and tyrosine) of a protein flip by 180° around the Cβ-Cγ axis (χ2 dihedral of the side chain), producing two symmetry-equivalent states. The study of ring flip dynamics with nuclear magnetic resonance (NMR) experiments helps to understand local conformational fluctuations. Ring flips are categorized as slow (milliseconds and onward) or fast (nanoseconds to near
Insulin-like growth factor-1 (IGF-1) is essential for normal brain development and regulates processesof vascular maturation. The pathogenesis of intraventricular hemorrhage (IVH) relates to the fragilityof the immature capillaries in the germinal matrix, and its inability to resist fluctuations in cerebralblood flow. In this work, using different experimental setups, we aimed to (i) establish an
Due to climate change and increasing pressures on resources, the demand for more energy-efficient buildings is increasing globally. Building information modeling (BIM) and building energy modeling (BEM) are two essential tools to make the necessary transition to net-zero energy buildings (NZEB). This article presents two case studies aiming to automate information from the BIM model to predict ann
Gut-derived antigens trigger immunoglobulin A (IgA) immune responses that are initiated by cognate B cells in Peyer’s patches (PPs). These cells colonize the subepithelial domes (SEDs) of the PPs and subsequently infiltrate pre-existing germinal centers (GCs). Here we defined the pre-GC events and the micro-anatomical site at which affinity-based B cell selection occurred in PPs. Using whole-organ
