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The global methylation profile and the mutational status of 633 specific epigenetic regulators were analyzed in the pediatric tumor clear cell sarcoma of the kidney (CCSK). Methylation array analyses of 30 CCSKs revealed CCSK tumor DNA to be globally hypermethylated compared to Wilms tumor, normal fetal kidney, and adult kidney. The aberrant methylation pattern of CCSKs was associated with activat
The combination of features from the public and private sectors in jointly owned companies imposes challenges to the governance and control mechanisms of these organisations, which have been criticised for lacking accountability. Where there is fragmented ownership, the interests of different owners need to be coordinated. The aim of this article is to consider how such companies can be governed i
This article studies continued childbearing and union stability among "power couples," or dual-career couples. The determinants of these events are analysed multivariately using longitudinal data on couples from population registers in Sweden, 1991–2005. Power couples are identified using their levels and fields of education, and their sectors of employment. Income and other variables are controll
Metabolic complications are prevalent in individuals treated with cranial radiotherapy (CRT) for childhood acute lymphoblastic leukemia (ALL). The hypothalamus is a master regulator of endocrine and metabolic control. The aim of this study was to investigate whether the hypothalamic volume would be associated to metabolic parameters in ALL survivors. Thirty-eight (21 women) survivors participated
BACKGROUND: The 1061delC single-nucleotide polymorphism (SNP) has been reported mostly in the context of the common A(2)[A201] allele and typically produces an A(2) phenotype. This study evaluated new A(weak) alleles, each containing 1061delC. STUDY DESIGN AND METHODS: Twenty samples were referred to our laboratory for analysis due to suspected A(weak) phenotypes originally detected at the referri
This study examines elaborate prayer practices among peasant communities in late medieval Sweden. The work focuses on the perspectives of ideals and practices, namely the standards of prayer, devotional prayer, and prayer in times of need and prayer cultures.
Popular Abstract in Swedish Fältskiktet gör skillnaden! Dynamiken av näringsämnen och organiskt material i bokskogens övre markskikt Frida Andreasson, Växtekologi och systematik, Lunds universitet Det övre markskiktet i bokskogen är markens mest biologiskt aktiva del. Därför är kunskapen om denna del av marken, dess egenskaper och kemi, angelägen. Särskilt viktig är kunskapen om mineraliseringeThe objective of this thesis was to quantify differences between adjacent patches with and without ground flora of Deschampsia flexuosa L. Trin or Anemone nemorosa L. in two acid European beech (Fagus sylvatica L.) forest floors in south-west of Sweden. The studies included soil properties and chemistry, N mineralisation and bioavailability of dissolved organic carbon (DOC), in soil leachates (SL)
The study accounts for recent developments in corporate voluntarism and assesses the evolving corporate social responsibility (CSR) regime. CSR proposes a new norm for how large businesses should approach complexity in a modern economy. The first chapter anchors the CSR discussion in a company law and corporate governance context. Emphasis is placed on managerial duties and the British Review of C
Popular Abstract in Swedish Insulinberoende diabetes mellitus (IDDM = Typ 1 diabetes), och kronisk sköldkörtelinflammation - autoimmun thyreoidit (AIT) anses idag vara orsakade av att de hormonproducerande cellerna angrips av kroppens eget immunsystem (sk. autoimmunitet). När sjukdomen ger sig till känna kliniskt finnes antikroppar (sk. autoantikroppar) riktade mot cellkomponenter i det hormonprodThe two most common autoimmune endocrine diseases in children are autoimmune thyroiditis (AIT) and Type 1 (insulin-dependent) diabetes mellitus (IDDM). Autoantibodies (ab) can be found several years before clinical diagnosis in both diseases. The aims of this study were to investigate the prevalence of thyroid ab in children with IDDM and in children with allergic diseases; to study islet ab and t
In this study we investigated how managers make strategical decisions in complex, dynamic, and real-time environments and in different decision domains. The managers we interviewed were usually ‘in charge’ of the tasks. Our results showed that the informants mostly constructed only one or two decision alternatives and that they did this to a large extent through communication with other persons, w
The Swedish state and its administrative organization experienced, like its European neighbours, an extensive development and transformation in the beginning of the 17th century. One part of the administration that for the first time was organised in a formal way was the postal services. This paper discuss the origins of national postal systems in relation to the development of bureaucratic and ad
