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Diversifications often proceed along highly conserved, evolutionary trajectories. These patterns of covariation arise in ontogeny, which raises the possibility that adaptive morphologies are biased towards trait covariations that resemble growth trajectories. Here, we test this prediction in the diverse clade of Anolis lizards by investigating the covariation of embryonic growth of 13 fore- and hi

During the Late Glacial, hunter-gatherers began using ceramic cooking containers in three separate geographic regions of East Asia: China, Japan and in the Russian Far East. While recent research has clarified the use of early pottery in Japan, very little is known about what led to the emergence of pottery in the other two areas, including the likely environmental, economic or cultural drivers. I

Understanding the emergence and development of coastal adaptations is a central theme in the archaeology of Maritime Northeast Asia. The capacity to harvest, store and share aquatic resources offered a novel economic strategy that could support greater sedentism and new forms of social life. In turn, growing reliance on the exploitation of rich coastal resources wouldhave generated powerful incent

The Pleistocene-Holocene transition brought turbulent times to human societies confronted by rapid climatic fluctuations, shifts inbiogeographic zones and the flooding of continental shelves. While the disappearance of Doggerland’s inhabited landscapes underthe grey waters of the North Sea marks the culmination of these changes for European Archaeologists, our aim is this paper is todraw parallels

Theorizing embeddedness requires sensitivity to the dynamic and multi-layered contexts that entrepreneurship is situated within. Social or network embeddedness offers explanation for how both social and for-profit entrepreneurs can leverage resources within their local environment. Institutional embeddedness is concerned with how the environment for entrepreneurship is shaped by social structures,

Introduction: The Models of Patient Engagement for Alzheimer's Disease (MOPEAD) project was conceived to explore innovative complementary strategies to uncover hidden prodromal and mild Alzheimer's disease (AD) dementia cases and to raise awareness both in the general public and among health professionals about the importance of early diagnosis. Methods: Four different strategies or RUNs were used

Background: By examining the health needs of the general population and utilising the potential of digitalisation as a driving force, new internet-based services need to be developed in occupational therapy. However, existing guidelines for the development of complex interventions provide scant information on how to develop internet-based interventions. Aim: The aim of this paper is to share exper

Improvement of structural efficiency in various materials is critically important for sustainable society development and the efficient use of natural resources. Recently, a lot of attention in science and engineering has been attracted to heterogeneous-structure materials because of high structural efficiency. However, strategies for the efficient design of heterogenous structures are still in th

Background and purpose: Inter-modality image registration between computed tomography (CT) and magnetic resonance (MR) images is associated with systematic uncertainties and the magnitude of these uncertainties is not well documented. The purpose of this study was to investigate the potential uncertainty of gold fiducial marker (GFM) registration for localized prostate cancer and to estimate the i

BACKGROUND: Whole-body and thoracic ionizing radiation exposure are both associated with the development of renal dysfunction. However, whether low-level environmental radiation from air pollution affects renal function remains unknown.OBJECTIVES: We investigated the association of particle radioactivity (PR) with renal function defined by the estimated glomerular filtration rate (eGFR) and chroni

increased amounts of starch and sugar have been added to the diet in the Western world during the last decades. undigested carbohydrates lead to bacterial fermentation and gas production with diffusion of water, causing abdominal bloating, pain and diarrhea. Therefore, dietary advice is the first line of treatment of irritable bowel syndrome (IBS), a disease characterized by abdominal pain and alt

In this Medium contribution, we take a closer look at the potential of exploiting the ordinary user’s digital (il)literacy in their search practices. We explore how the logic of search engines, and missing or low-quality data are vulnerable to extreme-right manipulations.

The essential enzyme ribonucleotide reductase (RNR) is highly regulated both at the level of overall activity and substrate specificity. Studies of class I, aerobic RNRs have shown that overall activity is downregulated by the binding of dATP to a small domain known as the ATP-cone often found at the N-terminus of RNR subunits, causing oligomerization that prevents formation of a necessary α2β2 co

Mild diseases and moderate stressors are seemingly harmless and are therefore often assumed to have negligible impact on Darwinian fitness. Here we argue that the effects of “benign” parasites and other moderate stressors may have a greater impact on lifespan and other fitness traits than generally thought. We outline the “accumulating costs” hypothesis which proposes that moderate strains on the

Mitochondrial translation is essentially bacteria-like, reflecting the bacterial endosymbiotic ancestry of the eukaryotic organelle. However, unlike the translation system of its bacterial ancestors, mitochondrial translation is limited to just a few mRNAs, mainly coding for components of the respiratory complex. The classical bacterial initiation factors (IFs) IF1, IF2 and IF3 are universal in ba

The number of consumers producing electricity at home, i.e., “prosumers”, is rapidly increasing in many European countries. This article analyses the electricity consumption and energy-saving behaviours of households that own photovoltaic (PV) systems in Sweden. Earlier studies of how home production of electricity affects consumption patterns are few and their results are mixed. We interviewed pr

This article reports on a search for dark matter pair production in association with a Higgs boson decaying to a pair of bottom quarks, using data from 20.3 fb-1 of pp collisions at a center-of-mass energy of 8 TeV collected by the ATLAS detector at the LHC. The decay of the Higgs boson is reconstructed as a high-momentum bb system with either a pair of small-radius jets, or a single large-radius

Background: There are but a few studies of how persons with autism perceive their bodies and movements. Difficulties in perceiving the surrounding world along with disturbed motor coordination and executive functions may affect physical and psychological development. Aims: To explore the experiences of body and movements in young adults with autism and how two physiotherapeutic instruments may cap