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Objective: Transitions in the spectrum of valvular heart diseases (VHDs) in developed countries over the 20th century have been reported from clinical case series, but large, contemporary population-based studies are lacking.Methods: We used nationwide registers to identify all patients with a first diagnosis of VHD at Swedish hospitals between 2003 and 2010. Age-stratified and sex-stratified inci
Regeneration of severed peripheral nerves is unfortunately often incomplete, due to loss of nerve fibers and neuroma formation. A new approach is presented with the intention of improving the conditions for nerve repair. In the first of the two stages, a pseudosynovial tube is formed around a silicone rubber rod, surrounded by a stainless steel spiral, which was placed in the backs of rats. This t
Aims: ST-depression at 24hECG has not been studied in relation to atrial fibrillation (AF) risk. We aimed to determine whether ST-depression at 24hECG was associated with incident AF in two Swedish population-based cohorts - a sub-cohort of the Malmö Diet and Cancer study (MDCS), and the cohort 'Men born in 1914', and to determine whether 24hECG could be used to predict AF development.Methods and
The presence of bacteria in the lower airways in COPD results in inflammation, further airway structural damage, and might lead to repeated exacerbations. We have previously shown that chronic colonization of Haemophilus influenzae during stable disease is related to increased inflammation, and we now aimed to relate previous findings of bacterial colonization and inflammation to the degree of rad
This work investigates the persistence of path dependent trajectories and institutional inertia between the European Union and Turkey, particularly in regards to how these dynamics shape the development of sustainability-focused discourse in the energy sector. It delves into further detail by examining how emerging fields of energy are framed within institutional discourse, and whether these dynam
A healthy diet has demonstrated its effectiveness in preventing globally rising lifestyle-related diseases including type 2 diabetes. Moreover, previous researches investigating polar lipids suggest that these compounds could potentially enhance metabolic variables associated with type 2 diabetes. Consequently, the present study assessed two commercial lecithin preparations, rich in polar lipids,
The historical record is an underutilised resource within many fields of biology, despite its unique uses. In this thesis, I have used information from entomological collections and species observation systems to investigate and elaborate on the distribution, habitat preferences and phenology of some rare and poorly known moths within the family of Gelechiidae. Like many other microlepidoptera, ge
Purpose – This study explores the assumptions of Sohl and Hill (2007) and Harrison and Mason (2007), and analyses if these can be empirically supported. This is done from the theoretical perspective of gender studies and explored how women BAs perceive themselves and understand the industry, based on their own educations, experiences and social capital. Methodology – This study follows a qualitati
Much has been written about Hemingway’s works from a feminist or queer perspective, including the relation between Hemingway’s biography and his representation of female characters, female domination and homosexuality. In comparison, the queer sub-field of transgender studies, which entails analyzing gender transgression and influence, has received little attention by scholars of Hemingway studies
IntroductionNine in ten of the world’s 1.74 million adolescents living with human immunodeficiency virus (ALHIV) live in Sub-Saharan Africa. Suboptimal adherence to antiretroviral therapy (ART) and poor viral suppression are important problems among adolescents. To guide intervention efforts in this regard, this review presented pooled estimates on the prevalence of adherence and how it is affecte
Hematopoiesis is regulated by the bone marrow (BM) stroma. However, cellular identities and functions of the different BM stromal elements in humans remain poorly defined. Based on single-cell RNA sequencing (scRNAseq), we systematically characterized the human non-hematopoietic BM stromal compartment and we investigated stromal cell regulation principles based on the RNA velocity analysis using s
Monoclonal antibody solutions are set to become a major therapeutic tool in the years to come, capable of targeting various diseases by clever design of their antigen binding site. However, the formulation of stable solutions suitable for patient self-administration typically presents challenges, as a result of the increase in viscosity that often occurs at high concentrations. Here, we establish
This longitudinal study examined the relationship between flexibility-activity and blood-pressure (BP) change among older adults in Japan. Our study included 452 older adults who took part in our survey in both 2012/2013 and 2017/2018. The seated systolic blood pressure (SBP) and diastolic BP (DBP) were measured both at baseline and at the 5 years follow-up. The frequencies of the different physic
Background: Cervical cancer is a major global health issue, with 89% of cases occurring in low- and middle-income countries (LMICs). Human papillomavirus (HPV) self-sampling tests have been suggested as an innovative way to improve cervical cancer screening uptake and reduce the burden of disease. The objective of this review was to examine the effect of HPV self-sampling on screening uptake compa
Syftet med detta uppdrag har varit att utvärdera hur data på vinterförluster hos honungsbin i Sverige samlas in och analyseras, samt ge förslag på förbättringarav övervakning och analys.Denna rapport innehåller• En sammanställning av faktorer som kan påverka vinterförluster hos honungsbin under svenska förhållanden• En beskrivning av nuvarande sätt att rapportera och analysera vinterförluster i SvThis report evaluates current collection and use of data on winter loss in honey bees in Sweden and is a commission from the Swedish Professional BeekepersAssociation. It includes an overview of factors which may influence winter loss in honey bees in Sweden. In Sweden, data on winter loss is collected by twoinstances, the COLOSS survey and the Swedish Beekeepers Association (SBR). We identify sev
In concentrated solutions of aqueous RbCl, all of the Rb+ and Cl– ions exist as contact ion pairs. This full structural assessment is derived from the refinement of three independent experimental measurements: the Rb and Cl K-edge X-ray absorption fine structure (XAFS) and the X-ray diffraction spectra (XRD). This simultaneous refinement of the XAFS and XRD data provides high accuracy since each m
Background: Despite its well-established positive effects, exercise-based cardiac rehabilitation (exCR) is underused in patients following an acute myocardial infarction (AMI). The aim of the study was to identify factors associated with non-Attendance at exCR in patients post-AMI in a large Swedish cohort. Methods: A total of 31,297 patients who have suffered an AMI, mean age 62.4 ± 4 years, were
Introduction: Globally, many adolescents suffer from mental health problems and related stigma. Assessing mental health stigma among youth is crucial to addressing this problem. The aim of this study was to examine the psychometric properties of a modified version of the Attitudes About Mental Illness and its Treatment (AAMIT) instrument and to describe attitudes according to the instrument, among
